相关论文: Viscoelastic Cahn--Hilliard models for tumour grow…
Recently we considered a stochastic discrete model which describes fronts of cells invading a wound \cite{KSS}. In the model cells can move, proliferate, and experience cell-cell adhesion. In this work we focus on a continuum description of…
We extend previous weak well-posedness results obtained in Frigeri et al. (2017) concerning a non-local variant of a diffuse interface tumor model proposed by Hawkins-Daarud et al. (2012). The model consists of a non-local Cahn--Hilliard…
A mathematical analysis of local and nonlocal phase-field models of tumor growth is presented that includes time-dependent Darcy-Forchheimer-Brinkman models of convective velocity fields and models of long-range cell interactions. A…
We study a phase field model proposed recently in the context of tumour growth. The model couples a Cahn-Hilliard-Brinkman (CHB) system with a elliptic reaction-diffusion equation for a nutrient. The fluid velocity, governed by the Brinkman…
Models of tumor growth, now commonly used, present several levels of complexity, both in terms of the biomedical ingredients and the mathematical description. The simplest ones contain competition for space using purely fluid mechanical…
We prove existence of weak solutions to a diffuse interface model describing the flow of a fluid through a deformable porous medium consisting of two phases. The system non-linearly couples Biot's equations for poroelasticity, including…
We consider the problem of the long time dynamics for a diffuse interface model for tumor growth. The model describes the growth of a tumor surrounded by host tissues in the presence of a nutrient and consists in a Cahn-Hilliard-type…
The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…
Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…
We prove the existence of a unique large-data global-in-time weak solution to a class of models of the form $\mathbf{u}_{tt} = \mathrm{div}(\mathbb{T}) + \mathbf{f}$ for viscoelastic bodies exhibiting strain-limiting behaviour, where the…
This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…
We consider a mathematical model coupling the Cahn-Hilliard system for phase separation with an additional equation describing the diffusion process of a chemical quantity whose concentration influences the physical process. The main…
We investigate the dynamics of a nonlinear model for tumor growth within a cellular medium. In this setting the "tumor" is viewed as a multiphase flow consisting of cancerous cells in either proliferating phase or quiescent phase and a…
We consider a mathematical model for the evolutionary dynamics of tumour cells in vascularised tumours under chemotherapy. The model comprises a system of coupled partial integro-differential equations for the phenotypic distribution of…
This paper deals with a general system of equations and conditions arising from a mathematical model of prostate cancer growth with chemotherapy and antiangiogenic therapy that has been recently introduced and analyzed (see [P. Colli et…
In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…
Recently, Jiang--Jiang (J. Differential Equations 282, 2021) showed the existence of unique strong solutions in spatial periodic domain (denoted by $\mathbb{T}^3$), whenever the elasticity coefficient is larger than the initial velocity…
This paper concerns a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis with possibly singular potentials, where the control and state variables are nonlinearly coupled. First, we…
We consider a local Cahn-Hilliard-type model for tumor growth as well as a nonlocal model where, compared to the local system, the Laplacian in the equation for the chemical potential is replaced by a nonlocal operator. The latter is…
We study one-dimensional viscoelastic phase transitions modeled by a Ginzburg--Landau energy with a non-convex cubic stress-strain law. Extending the isothermal model, we couple the momentum equation to a heat equation for the temperature…