相关论文: Viscoelastic Cahn--Hilliard models for tumour grow…

We consider nonlinear viscoelastic materials of Kelvin-Voigt type with stored energies satisfying an Andrews-Ball condition, allowing for non convexity in a compact set. Existence of weak solutions with deformation gradients in $H^1$ is…

In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for…

We propose a mathematical model that combines elastic, viscous and porous effects with growth or shrinkage due to microstructural changes. This phenomenon is important in tissue or tumor growth, as well as in dermal contraction. Although…

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

Using a novel modeling approach based on the so-called environmental stress level (ESL), we develop a mathematical model to describe systematically the collective influence of oxygen concentration and stiffness of the extracellular matrix…

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

We study a model for a fluid showing viscoelastic and viscoplastic behavior, which describes the flow in terms of the fluid velocity and an internal stress. This stress tensor is transported via the Zaremba--Jaumann rate, and it is subject…

We study the effect of a viscous dissipation on the Cauchy problem for a Cattaneo-type model in nonlinear acoustics, established by applying the Lighthill approximation for the viscous or inviscid fluid model. The contribution of this paper…

We show here the global, in time, regularity of the three dimensional viscous Camassa-Holm (Lagrangian Averaged Navier-Stokes-alpha) equations. We also provide estimates, in terms of the physical parameters of the equations, for the…

This paper presents a macroscopic theory, alongside its numerical implementation, aimed at describing, explaining, and predicting the nucleation and propagation of fracture in viscoelastic materials subjected to quasistatic loading…

The study of long-term dynamics for numerical solutions of nonlinear evolution equations, particularly phase field models, has consistently garnered considerable attention. The Cahn-Hilliard (CH) equation is one of the most important phase…

Well-posedness is proved for the stochastic viscous Cahn-Hilliard equation with homogeneous Neumann boundary conditions and Wiener multiplicative noise. The double-well potential is allowed to have any growth at infinity (in particular,…

We give a very short introduction to discrete and continuum models for the evolutionary and spatial dynamics of cancer through two case studies: a model for the evolutionary dynamics of cancer cells under cytotoxic therapy and a model for…

We propose a multiscale chemo-mechanical model of cancer tumour development in an epithelial tissue. The model is based on transformation of normal cells into the cancerous state triggered by a local failure of spatial synchronisation of…

Regularity properties of solutions for a class of quasi-stationary models in one spatial dimension for stress-modulated growth in the presence of a nutrient field are proven. At a given point in time the configuration of a body after pure…

A typical phase field approach for describing phase separation and coarsening phenomena in alloys is the Cahn-Hilliard model. This model has been generalized to the so-called Cahn-Larch\'e system by combining it with elasticity to capture…

We consider a system of evolutionary equations that is capable of describing certain viscoelastic effects in linearized yet nonlinear models of solid mechanics. The essence of the paper is that the constitutive relation, involving the…

Results are presented from numerical experiments aiming at the computation of stochastic phase-field models for phase transformations by coarse-graining molecular dynamics. The studied phase transformations occur between a solid crystal and…

Tumour spheroids have been the focus of a variety of mathematical models, ranging from Greenspan's classical study of the 1970s through to contemporary agent-based models. Of the many factors that regulate spheroid growth, mechanical…

Hypoxia and acidity act as environmental stressors promoting selection for cancer cells with a more aggressive phenotype. As a result, a deeper theoretical understanding of the spatio-temporal processes that drive the adaptation of tumour…