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相关论文: Viscoelastic Cahn--Hilliard models for tumour grow…

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In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…

数值分析 · 数学 2024-06-21 Harald Garcke , Dennis Trautwein

Mechanical effects have mostly been neglected so far in phase field tumour models that are based on a Cahn-Hilliard approach. In this paper we study a macroscopic mechanical model for tumour growth in which cell-cell adhesion effects are…

偏微分方程分析 · 数学 2021-01-20 Harald Garcke , Kei Fong Lam , Andrea Signori

In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

数值分析 · 数学 2022-05-09 Harald Garcke , Dennis Trautwein

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

偏微分方程分析 · 数学 2025-10-09 Giulia Cavalleri

We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a…

偏微分方程分析 · 数学 2019-11-01 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Emanuel Sitka

We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…

偏微分方程分析 · 数学 2025-12-18 Cecilia Cavaterra , Matteo Fornoni , Maurizio Grasselli , Benoît Perthame

We study a Cahn--Hilliard two-phase model describing the flow of two viscoelastoplastic fluids, which arises in geodynamics. A phase-field variable indicates the proportional distribution of the two fluids in the mixture. The motion of the…

偏微分方程分析 · 数学 2025-10-01 Fan Cheng , Robert Lasarzik , Marita Thomas

We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the…

偏微分方程分析 · 数学 2022-06-22 Patrik Knopf , Andrea Signori

In this work, we present and analyze a system of PDEs, which models tumor growth by considering chemotaxis, active transport, and random effects. The stochasticity of the system is modelled by random initial data and Wiener noises that…

偏微分方程分析 · 数学 2023-12-12 Marvin Fritz , Luca Scarpa

We develop a linear fully discrete structure-preserving finite element method for a diffuse-interface model of tumour growth. The system couples a Cahn--Hilliard type equation with a nonlinear reaction-diffusion equation for nutrient…

数值分析 · 数学 2025-10-23 Agus L. Soenjaya , Ping Lin , Thanh Tran

In this work, we analyze a diffuse-interface model for tumor growth, subject to multiplicative white noises, posed on a bounded domain $\mathcal{O} \subset \mathbb{R}^d$, $d=2,3$. The model couples a stochastic incompressible convective…

偏微分方程分析 · 数学 2026-05-29 Kalpana Rawat , Kumarasamy Sakthivel

We consider a diffuse interface model of tumor growth proposed by A.~Hawkins-Daruud et al. This model consists of the Cahn-Hilliard equation for the tumor cell fraction $\varphi$ nonlinearly coupled with a reaction-diffusion equation for…

偏微分方程分析 · 数学 2014-12-05 Sergio Frigeri , Maurizio Grasselli , Elisabetta Rocca

In this work, we study a model consisting of a Cahn-Hilliard-type equation for the concentration of tumour cells coupled to a reaction-diffusion type equation for the nutrient density and a Brinkman-type equation for the velocity. We equip…

偏微分方程分析 · 数学 2018-11-19 Matthias Ebenbeck , Harald Garcke

We study the existence of weak solutions to a Cahn--Hilliard--Darcy system coupled with a convection-reaction-diffusion equation through the fluxes, through the source terms and in Darcy's law. The system of equations arises from a mixture…

偏微分方程分析 · 数学 2016-10-25 Harald Garcke , Kei Fong Lam

A phase field model for tumour growth is introduced that is based on a Brinkman law for convective velocity fields. The model couples a convective Cahn-Hilliard equation for the evolution of the tumour to a reaction-diffusion-advection…

偏微分方程分析 · 数学 2021-09-07 Matthias Ebenbeck , Harald Garcke , Robert Nürnberg

We propose a new Cahn-Hilliard phase field model coupled to incompressible viscoelasticity at large strains, obtained from a diffuse interface mixture model and formulated in the Eulerian configuration. A new kind of diffusive…

偏微分方程分析 · 数学 2023-01-23 Abramo Agosti , Pierluigi Colli , Harald Garcke , Elisabetta Rocca

We analyze a phase field model for tumor growth consisting of a Cahn-Hilliard-Brinkman system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion equation for a chemical species acting as a nutrient. The…

偏微分方程分析 · 数学 2023-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We consider a diffuse interface model for tumour growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the…

偏微分方程分析 · 数学 2016-05-26 Harald Garcke , Kei Fong Lam

We study the existence of weak solutions to a mixture model for tumour growth that consists of a Cahn--Hilliard--Darcy system coupled with an elliptic reaction-diffusion equation. The Darcy law gives rise to an elliptic equation for the…

偏微分方程分析 · 数学 2018-03-26 Harald Garcke , Kei Fong Lam

We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…

偏微分方程分析 · 数学 2025-10-13 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca
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