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相关论文: Viscoelastic Cahn--Hilliard models for tumour grow…

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We propose a new class of phase field models coupled to viscoelasticity with large deformations, obtained from a diffuse interface mixture model composed by a phase with elastic properties and a liquid phase. The model is formulated in the…

偏微分方程分析 · 数学 2022-04-12 Abramo Agosti , Pierluigi Colli , Harald Garcke , Elisabetta Rocca

In this paper, we tackle the problem of reconstructing earlier tumour configurations starting from a single spatial measurement at a later time. We describe the tumour evolution through a diffuse interface model coupling a…

偏微分方程分析 · 数学 2024-09-25 Abramo Agosti , Elena Beretta , Cecilia Cavaterra , Matteo Fornoni , Elisabetta Rocca

We study the Cahn-Hilliard-Biot model with respect to its mathematical well-posedness. The system models flow through deformable porous media in which the solid material has two phases with distinct material properties. The two phases of…

偏微分方程分析 · 数学 2024-10-04 Marvin Fritz

We prove existence of weak solutions and weak-strong uniqueness for a mathematical model which couples the evolution of a phase-parameter $\varphi$ satisfying a Cahn-Hilliard type relation with the one of an additional variable $\sigma$…

偏微分方程分析 · 数学 2026-04-21 Robert Lasarzik , Elisabetta Rocca , Giulio Schimperna

Phase field models recently gained a lot of interest in the context of tumour growth models. Typically Darcy-type flow models are coupled to Cahn-Hilliard equations. However, often Stokes or Brinkman flows are more appropriate flow models.…

偏微分方程分析 · 数学 2018-07-03 Matthias Ebenbeck , Harald Garcke

In the present work, we develop a comprehensive and rigorous analytical framework for a non-local phase-field model that describes tumour growth dynamics. The model is derived by coupling a non-local Cahn-Hilliard equation with a parabolic…

偏微分方程分析 · 数学 2025-03-14 Maurizio Grasselli , Luca Melzi , Andrea Signori

We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…

偏微分方程分析 · 数学 2023-11-23 Abramo Agosti , Andrea Signori

In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…

偏微分方程分析 · 数学 2026-02-16 Pierluigi Colli , Elisabetta Rocca , Jürgen Sprekels

We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…

偏微分方程分析 · 数学 2024-07-29 Matteo Fornoni

In this paper, we study a system of three evolutionary operator equations involving fractional powers of selfadjoint, monotone, unbounded, linear operators having compact resolvents. This system constitutes a generalization of a phase field…

偏微分方程分析 · 数学 2019-06-27 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

Using basic thermodynamic principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalises earlier models and in…

偏微分方程分析 · 数学 2016-06-06 Harald Garcke , Kei Fong Lam , Emanuel Sitka , Vanessa Styles

In this paper we perform an asymptotic analysis for two different vanishing viscosity coefficients occurring in a phase field system of Cahn-Hilliard type that was recently introduced in order to approximate a tumor growth model. In…

偏微分方程分析 · 数学 2015-02-02 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Juergen Sprekels

The paper deals with a phase field system of Cahn-Hilliard type. For positive viscosity coefficients, the authors prove an existence and uniqueness result and study the long time behavior of the solution by assuming the nonlinearities to be…

偏微分方程分析 · 数学 2014-03-24 Pierluigi Colli , Gianni Gilardi , Danielle Hilhorst

We consider an evolutionary PDE system coupling the Cahn-Hilliard equation with singular potential, mass source and transport effects, to a Brinkman-type relation for the macroscopic velocity field and to a further equation describing the…

偏微分方程分析 · 数学 2024-11-20 Giulio Schimperna

We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…

偏微分方程分析 · 数学 2017-05-04 Harald Garcke , Kei Fong Lam

In this work, we develop a structure-preserving numerical scheme for a Cahn-Hilliard-Darcy model that describes tumor growth in a fluid-saturated porous medium. First, we derive a physically consistent model from the general framework…

We propose a new type of diffuse interface model describing the evolution of a tumor mass under the effects of a chemical substance (e.g., a nutrient or a drug). The process is described by utilizing the variables $\varphi$, an order…

偏微分方程分析 · 数学 2022-02-23 Elisabetta Rocca , Giulio Schimperna , Andrea Signori

This paper is concerned with a phase field system of Cahn-Hilliard type that is related to a tumor growth model and consists of three equations in terms of the variables order parameter, chemical potential and nutrient concentration. This…

偏微分方程分析 · 数学 2015-03-04 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Jürgen Sprekels

Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…

偏微分方程分析 · 数学 2016-02-17 Benoit Perthame , Nicolas Vauchelet

We study a fully discrete finite element approximation of a model for unsteady flows of rate-type viscoelastic fluids with stress diffusion in two and three dimensions. The model consists of the incompressible Navier--Stokes equation for…

数值分析 · 数学 2024-06-21 Dennis Trautwein