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We study a nonlocal adhesion model for two interacting tumor cell phenotypes, combining diffusion, pairwise interactions, and random phenotypic switching. The system admits a microscopic diffusion--jump particle description whose mean-field…

偏微分方程分析 · 数学 2026-03-16 Myeongju Chae , Young-Pil Choi

A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…

数值分析 · 数学 2019-02-19 Gopikrishnan C. Remesan

This paper presents an existence result for the anisotropic Cahn--Hilliard equation characterized by a potentially concentration-dependent degenerate mobility taking into account an anisotropic energy. The model allows for the degeneracy of…

偏微分方程分析 · 数学 2025-02-20 Harald Garcke , Patrik Knopf , Andrea Signori

We find an explicit form of weak solutions to a Riemann problem for a degenerate semilinear parabolic equation with piecewise constant diffusion coefficient. It is demonstrated that the phase transition lines (free boundaries) correspond to…

偏微分方程分析 · 数学 2022-11-01 Evgeny Yu. Panov

We study a nonlocal Cahn-Hilliard model for a multicomponent mixture with cross-diffusion effects and degenerate mobility. The nonlocality is described by means of a symmetric singular kernel. We define a notion of weak solution adapted to…

偏微分方程分析 · 数学 2026-05-22 Elisa Davoli , Greta Marino , Jan-Frederik Pietschmann

Volume-filling cross-diffusion equations for the components of a tissue structure are formally derived from mass conservation laws and force balances for the interphase pressures and viscous drag forces in a multiphase approach. The…

偏微分方程分析 · 数学 2026-04-03 Ansgar Jüngel , Cordula Reisch , Sara Xhahysa

We consider 1D dissipative transport equations with nonlocal velocity field: \[ \theta_t+u\theta_x+\delta u_{x} \theta+\Lambda^{\gamma}\theta=0, \quad u=\mathcal{N}(\theta), \] where $\mathcal{N}$ is a nonlocal operator given by a Fourier…

偏微分方程分析 · 数学 2018-04-25 Hantaek Bae , Rafael Granero-Belinchón , Omar Lazar

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

动力系统 · 数学 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

We prove existence of weak solutions for a diffuse interface model for the flow of two viscous incompressible Newtonian fluids with different densities in a bounded domain in two and three space dimensions. In contrast to previous works, we…

偏微分方程分析 · 数学 2019-11-21 Helmut Abels , Yutaka Terasawa

A chemotaxis system possibly containing rotational components of the cross-diffusive flux is studied under no-flux boundary conditions in a bounded domain $\Omega\subset R^n$, $n\ge 1$, with smooth boundary, where the evolution of the…

偏微分方程分析 · 数学 2015-06-19 Michael Winkler

A nutrient-limited model for avascular cancer growth including cell proliferation, motility and death is presented. The model qualitatively reproduces commonly observed morphologies for primary tumors, and the simulated patterns are…

统计力学 · 物理学 2011-03-09 S. C. Ferreira Junior , M. L. Martins , M. J. Vilela

In this paper, we propose a new mathematical model nonlinear reaction-diffusion PDE's describing the dynamics of propagation of cancer. Here the mixed problem for the proposed PDE's is investigated and by applying obtained results…

偏微分方程分析 · 数学 2022-01-10 Kamal N. Soltanov

The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…

偏微分方程分析 · 数学 2015-07-06 Inwon C. Kim , Benoit Perthame , Panagiotis E. Souganidis

We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…

偏微分方程分析 · 数学 2025-12-18 Cecilia Cavaterra , Matteo Fornoni , Maurizio Grasselli , Benoît Perthame

In this paper, we consider a mathematical model for the invasion of host tissue by tumour cells in a $d$-dimensional bounded domain, $d\leq 3$. This model consists of a system of differential equations describing the evolution of cancer…

Systems of the type $$\begin{cases} u_t = \nabla \cdot (D_1(u) \nabla u - S_1(u) \nabla v) + f_1(u, v),\\ v_t = \nabla \cdot (D_2(v) \nabla v + S_2(v) \nabla u) + f_2(u, v) \end{cases} \qquad (\star)$$ can be used to model pursuit-evasion…

偏微分方程分析 · 数学 2022-01-19 Mario Fuest

We consider weak solutions for a diffuse interface model of two non-Newtonian viscous, incompressible fluids of power-law type in the case of different densities in a bounded, sufficiently smooth domain. This leads to a coupled system of a…

偏微分方程分析 · 数学 2017-01-03 Helmut Abels , Dominic Breit

In this article, we present a multispecies reaction-advection-diffusion partial differential equation (PDE) coupled with linear elasticity for modeling tumor growth. The model aims to capture the phenomenological features of glioblastoma…

医学物理 · 物理学 2019-05-28 Shashank Subramanian , Amir Gholami , George Biros

We consider a haptotaxis cancer invasion model that includes two families of cancer cells. Both families, migrate on the extracellular matrix and proliferate. Moreover the model describes an epithelial-to-mesenchymal-like transition between…

偏微分方程分析 · 数学 2023-03-01 Jan Giesselmann , Niklas Kolbe , Maria Lukacova-Medvidova , Nikolaos Sfakianakis

We consider a class of cross diffusion systems with degenerate (or porous media type) diffusion which is inspired by models in mathematical biology/ecology with zero self diffusions. Known techniques for scalar equations are no longer…

偏微分方程分析 · 数学 2019-09-12 Dung Le