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Motivated by an ongoing collaboration with clinical oncologists and pathologists, we develop a hybrid partial differential equation--ordinary differential equation (PDE--ODE) framework that captures (i) competition between susceptible and…

偏微分方程分析 · 数学 2026-01-26 Jiguang Yu , Louis Shuo Wang , Zonghao Liu , Jingfeng Liu

This paper is devoted to the design and analysis of a numerical algorithm for approximating solutions of a degenerate cross-diffusion system, which models particular instances of taxis-type migration processes under local sensing…

数值分析 · 数学 2025-10-09 Juan Vicente Gutiérrez-Santacreu

We study the (generalized) one-dimensional population model developed by Anguige \& Schmeiser [1], which reflects cell-cell adhesion and volume filling under no-flux boundary condition. In this generalized model, depending on the adhesion…

偏微分方程分析 · 数学 2024-09-11 Hyung Jun Choi , Seonghak Kim , Youngwoo Koh

We consider the chemotaxis-fluid system \begin{align}\label{star}\tag{$\diamondsuit$} \left\{ \begin{array}{r@{\,}c@{\,}c@{\ }l@{\quad}l@{\quad}l@{\,}c} n_{t}&+&u\cdot\!\nabla n&=\Delta n^m-\nabla\!\cdot(n\nabla c),\ &x\in\Omega,& t>0,\\…

偏微分方程分析 · 数学 2018-08-06 Tobias Black

In this paper we study a recently derived mathematical model for nonlinear propagation of waves in the atmosphere, for which we establish the local well-posedness in the setting of classical solutions. This is achieved by formulating the…

偏微分方程分析 · 数学 2024-04-26 Bogdan-Vasile Matioc , Luigi Roberti

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

In this paper we consider chemotherapy in a spatial model of tumor growth. The model, which is of reaction-diffusion type, takes into account the complex interactions between the tumor and surrounding stromal cells by including densities of…

In this paper we study a cross-diffusion system whose coefficient matrix is non-symmetric and degenerate. The system arises in the study of tissue growth with autophagy. The existence of a weak solution is established. We also investigate…

偏微分方程分析 · 数学 2021-06-22 Jian-Guo Liu , Xiangsheng Xu

In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…

偏微分方程分析 · 数学 2021-08-31 Xu'an Dou , Jian-Guo Liu , Zhennan Zhou

Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…

组织与器官 · 定量生物学 2019-07-16 Joe Eyles , John F. King , Vanessa Styles

We revisit a classical continuum model for the diffusion of multiple species with size-exclusion constraint, which leads to a degenerate nonlinear cross-diffusion system. The purpose of this article is twofold: first, it aims at a…

偏微分方程分析 · 数学 2022-08-04 Katharina Hopf , Martin Burger

Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…

偏微分方程分析 · 数学 2023-11-01 Xu'an Dou , Chengfeng Shen , Zhennan Zhou

In this work, we study the Neumann initial boundary value problem for a three-component chemotaxis model in any dimensional bounded and smooth domains; this model is used to describe the branching of capillary sprouts during angiogenesis.…

偏微分方程分析 · 数学 2023-01-10 Jiawei Chu , Haiyang Jin , Tian Xiang

The aim of this paper is to prove global in time existence of weak solutions for a viscoelastic phase separation. We consider the case with singular potentials and degenerate mobilities. Our model couples the diffusive interface model with…

偏微分方程分析 · 数学 2022-08-31 Aaron Brunk , Maria Lukacova-Medvidova

In this article we prove the global existence of weak solutions for a diffuse interface model in a bounded domain (both in 2D and 3D) involving incompressible magnetic fluids with unmatched densities. The model couples the incompressible…

偏微分方程分析 · 数学 2021-06-09 Martin Kalousek , Sourav Mitra , Anja Schlömerkemper

In this paper, we consider the Dirichlet problem of three-dimensional inhomogeneous incompressible micropolar equations with density-dependent viscosity. Under the assumption that the coefficients are power functions of the density, we…

偏微分方程分析 · 数学 2025-05-13 Peng Lu , Yuanyuan Qiao

We introduce an extension of the concept of renormalised solutions for entropy-dissipating reaction-diffusion systems due to J. Fischer (Arch. Ration. Mech. Anal. 218, 2015) to systems coupled by nonlinear interface conditions. For this…

偏微分方程分析 · 数学 2026-02-26 Katharina Hopf , Bao Quoc Tang

We study the asymptotic behaviour of a system of nonlinear reaction--diffusion--advection equations in a domain consisting of two bulk regions connected via microscopic channels distributed within a thin membrane. Both the width of the…

偏微分方程分析 · 数学 2025-12-15 Lucas M. Fix , Gianna Götzmann , Malte A. Peter , Jan-F. Pietschmann

This paper studies the existence and asymptotic behavior of global weak solutions for a thin film equation with insoluble surfactant under the influence of gravitational, capillary and van der Waals forces. We prove the existence of global…

偏微分方程分析 · 数学 2019-08-21 Gabriele Bruell , Rafael Granero-Belinchón

We study a nonlinear system coupling the Darcy-Forchheimer-Brinkman equations with a convection-diffusion-reaction equation, arising in reactive transport through porous media. The model features a nonlinear viscosity coupling, Forchheimer…

偏微分方程分析 · 数学 2026-01-27 Sahil Kundu , Manmohan Vashisth , Manoranjan Mishra