相关论文: Global weak solutions to a strongly degenerate hap…
We analyze the mathematical properties of a multi-species biofilm cross-diffusion model together with very general reaction terms and mixed Dirichlet-Neumann boundary conditions on a bounded domain. This model belongs to the class of…
We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…
Starting from a two-scale description involving receptor binding dynamics and a kinetic transport equation for the evolution of the cell density function under velocity reorientations, we deduce macroscopic models for glioma invasion…
Glioma, an aggressive brain malignancy characterized by rapid progression and its poor prognosis, poses significant challenges for accurate evolution prediction. These challenges are exacerbated by sparse, irregularly acquired longitudinal…
Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…
We study a thermodynamically consistent diffuse-interface model that describes the motion of two macroscopically immiscible, incompressible, and viscous Newtonian fluids with unmatched densities. This model is compatible with continuum…
A class of parabolic cross-diffusion systems modeling the interaction of an arbitrary number of population species is analyzed in a bounded domain with no-flux boundary conditions. The equations are formally derived from a random-walk…
A stochastic hierarchical model for the evolution of low grade gliomas is proposed. Starting with the description of cell motion using piecewise diffusion Markov processes (PDifMPs) at the cellular level, we derive an equation for the…
In this paper, we study an initial boundary value problem of the Cahn-Hilliard-Darcy system with a non-autonomous mass source term $S$ that models tumor growth. We first prove the existence of global weak solutions as well as the existence…
Diffuse gliomas are highly infiltrative tumors whose early diagnosis and follow-up usually rely on magnetic resonance imaging (MRI). However, the limited sensitivity of this technique makes it impossible to directly assess the extent of the…
We consider a continuum mechanical model of cell invasion through thin membranes. The model consists of a transmission problem for cell volume fraction complemented with continuity of stresses and mass flux across the surfaces of the…
We prove nonuniqueness of weak solutions to multi-dimensional generalisation of the Aw-Rascle model of vehicular traffic. Our generalisation includes the velocity offset in a form of gradient of density function, which results in a…
This paper considers the homogeneous Neumann initial-boundary value problem for Alopecia Areata chemotaxis model with weakly singular sensitivity. For any appropriately regular initial conditions,it is shown that the problem admits a global…
We consider an initial-boundary value problem for the incompressible chemotaxis-Navier-Stokes equations generalizing the porous-medium-type diffusion model $ \quad n_t+u\cdot\nabla n=\Delta n^m-\nabla\cdot(n\chi(c)\nabla c), $ $ \quad…
This paper is devoted to global existence of weak solutions to the following degenerate kinetic model of chemotaxis \begin{equation} \begin{cases}\label{chemo0} u_t=\Delta (\gamma (v)u) \tau v_{t}=\Delta v-v+u \end{cases} \end{equation}in a…
We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…
We study a thermodynamically consistent diffuse interface model that describes the motion of a two-phase flow of two viscous incompressible Newtonian fluids with unmatched densities and a soluble surfactant in a bounded domain of two or…
We propose a two-component reaction-transport model for the migration-proliferation dichotomy in the spreading of tumor cells. By using a continuous time random walk (CTRW) we formulate a system of the balance equations for the cancer cells…
In a smoothly bounded domain $\Omega \subset \mathbb{R}^N$ $(N\in \mathbb{N})$, a no-flux initial-boundary value problem for the degenerate chemotaxis system with volume-filling effects, \begin{align*} u_t = \nabla \cdot (D(u,v) \nabla u -…
A spectral-fractional Cahn-Hilliard cross-diffusion system, which describes the pre-patterning of lymphatic vessel morphology in collagen gels, is studied. The model consists of two higher-order quasilinear parabolic equations and describes…