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相关论文: On a modified Cahn-Hilliard-Brinkman model with ch…

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We analyze a phase field model for tumor growth consisting of a Cahn-Hilliard-Brinkman system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion equation for a chemical species acting as a nutrient. The…

偏微分方程分析 · 数学 2023-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the…

偏微分方程分析 · 数学 2022-06-22 Patrik Knopf , Andrea Signori

In this work, we study a model consisting of a Cahn-Hilliard-type equation for the concentration of tumour cells coupled to a reaction-diffusion type equation for the nutrient density and a Brinkman-type equation for the velocity. We equip…

偏微分方程分析 · 数学 2018-11-19 Matthias Ebenbeck , Harald Garcke

We prove existence of weak solutions and weak-strong uniqueness for a mathematical model which couples the evolution of a phase-parameter $\varphi$ satisfying a Cahn-Hilliard type relation with the one of an additional variable $\sigma$…

偏微分方程分析 · 数学 2026-04-21 Robert Lasarzik , Elisabetta Rocca , Giulio Schimperna

We propose a new type of diffuse interface model describing the evolution of a tumor mass under the effects of a chemical substance (e.g., a nutrient or a drug). The process is described by utilizing the variables $\varphi$, an order…

偏微分方程分析 · 数学 2022-02-23 Elisabetta Rocca , Giulio Schimperna , Andrea Signori

We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…

偏微分方程分析 · 数学 2023-11-23 Abramo Agosti , Andrea Signori

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

偏微分方程分析 · 数学 2025-10-09 Giulia Cavalleri

We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…

偏微分方程分析 · 数学 2017-05-04 Harald Garcke , Kei Fong Lam

Phase field models recently gained a lot of interest in the context of tumour growth models. Typically Darcy-type flow models are coupled to Cahn-Hilliard equations. However, often Stokes or Brinkman flows are more appropriate flow models.…

偏微分方程分析 · 数学 2018-07-03 Matthias Ebenbeck , Harald Garcke

We consider a mathematical model coupling the Cahn-Hilliard system for phase separation with an additional equation describing the diffusion process of a chemical quantity whose concentration influences the physical process. The main…

偏微分方程分析 · 数学 2025-11-17 Giulio Schimperna , Antonio Segatti

A phase field model for tumour growth is introduced that is based on a Brinkman law for convective velocity fields. The model couples a convective Cahn-Hilliard equation for the evolution of the tumour to a reaction-diffusion-advection…

偏微分方程分析 · 数学 2021-09-07 Matthias Ebenbeck , Harald Garcke , Robert Nürnberg

We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a…

偏微分方程分析 · 数学 2019-11-01 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Emanuel Sitka

In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

数值分析 · 数学 2022-05-09 Harald Garcke , Dennis Trautwein

In this work, we present and analyze a system of PDEs, which models tumor growth by considering chemotaxis, active transport, and random effects. The stochasticity of the system is modelled by random initial data and Wiener noises that…

偏微分方程分析 · 数学 2023-12-12 Marvin Fritz , Luca Scarpa

This paper provides a unified mathematical analysis of a family of non-local diffuse interface models for tumor growth describing evolutions driven by long-range interactions. These integro-partial differential equations model cell-to-cell…

偏微分方程分析 · 数学 2021-07-07 Luca Scarpa , Andrea Signori

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

最优化与控制 · 数学 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

偏微分方程分析 · 数学 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…

偏微分方程分析 · 数学 2025-10-13 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca

We consider a diffuse interface model for tumour growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the…

偏微分方程分析 · 数学 2016-05-26 Harald Garcke , Kei Fong Lam

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

最优化与控制 · 数学 2021-10-12 Matthias Ebenbeck , Patrik Knopf
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