相关论文: Stability and bifurcations in a model of antigenic…

Effects of immune delay on symmetric dynamics are investigated within a model of antigenic variation in malaria. Using isotypic decomposition of the phase space, stability problem is reduced to the analysis of a cubic transcendental…

We present a deterministic mathematical model for malaria transmission with waning immunity. The model consists of five non-linear system of differential equations. We used next generation matrix to derive the basic reproduction number…

An epidemic model with distributed time delay is derived to describe the dynamics of infectious diseases with varying immunity. It is shown that solutions are always positive, and the model has at most two steady states: disease-free and…

We investigate an epidemiological model that incorporates waning of immunity at the individual level and boosting of the immune system upon re-exposure to the pathogen. When immunity is fully restored upon boosting, the system can be…

This paper proposes and analyzes a malaria transmission model structured by the chronological age of the human host population. The model couples an age-structured SIRS system for humans, incorporating waning immunity, with an SI system for…

We investigate positive steady states of an indefinite superlinear reaction-diffusion equation arising from population dynamics, coupled with a nonlinear boundary condition. Both the equation and the boundary condition depend upon a…

The influence of time-dependent perturbations on an autonomous Hamiltonian system with an equilibrium of center type is considered. It is assumed that the perturbations decay at infinity in time and vanish at the equilibrium of the…

Many infectious diseases are comprised of multiple strains with examples including Influenza, tuberculosis, and Dengue virus. The time evolution of such systems is linked to a complex landscape shaped by interactions between competing…

This paper investigates the deterministic extinction and permanence of a family of SEIRS malaria models with multiple random delays, and with a general nonlinear incidence rate. The conditions for the extinction and permanence of the…

In this paper, we derive and analyze a compartmental model for the control of arboviral diseases which takes into account an imperfect vaccine combined with individual protection and some vector control strategies already studied in the…

We establish some properties of a within host mathematical model of malaria proposed by Recker et al which includes the role of the immune system during the infection. The model accounts for the antigenic variation exhibited by the malaria…

In this paper, we discussed an infinitely distributed delayed viral infection model with nonlinear immune response and general incidence rate. We proved the existence and uniqueness of the equilibria. By using the Lyapunov functional and…

A cross-diffusion system modeling the information herding of individuals is analyzed in a bounded domain with no-flux boundary conditions. The variables are the species' density and an influence function which modifies the information state…

We consider the SIRWJS epidemiological model that includes the waning and boosting of immunity via secondary infections. We carry out combined analytical and numerical investigations of the dynamics. The formulae describing the existence…

We consider a model of antiviral immune response proposed in the works of G.I. Marchuk. The model is described by a system of delay differential equations. The asymptotic stability of a stationary solution to the system corresponding to a…

The aim of this work is to study the effect of diffusion on the stability of the equilibria in a general two-components reaction-diffusion system with Neumann boundary conditions in the space of continuous functions. As by product, we…

In mathematical studies of the dynamics of multi-strain diseases caused by antigenically diverse pathogens, there is a substantial interest in analytical insights. Using the example of a generic model of multi-strain diseases with…

In contrast to the many theoretical studies on the transmission of human-mosquitoes malaria infection, few studies have considered a multiple structure model formulations including (i) the chronological age of humans and mosquitoes…

In this paper, a mathematical model of pneumococcal pneumonia with time delays is proposed. The stability theory of delay differential equations is used to analyze the model. The results show that the disease-free equilibrium is…

A parameter-dependent model involving nonlinear diffusion for an age-structured population is studied. The parameter measures the intensity of the mortality. A bifurcation approach is used to establish existence of positive equilibrium…