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This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

偏微分方程分析 · 数学 2013-03-18 Shangbin Cui

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…

偏微分方程分析 · 数学 2008-06-10 Junde Wu , Shangbin Cui

In this paper we study asymptotic behavior of solutions for a multidimensional free boundary problem modelling the growth of nonnecrotic tumors. We first establish a general result for differential equations in Banach spaces possessing a…

偏微分方程分析 · 数学 2007-12-18 Shangbin Cui

This paper is concerned with a multi-dimensional free boundary problem modeling the growth of a tumor with two species of cells: proliferating cells and quiescent cells. This free boundary problem has a unique radial stationary solution. By…

偏微分方程分析 · 数学 2015-06-17 Shangbin Cui

This paper aims at proving asymptotic stability of the radial stationary solution of a free boundary problem modeling the growth of nonnecrotic tumors with fluid-like tissues. In a previous paper we considered the case where the nutrient…

偏微分方程分析 · 数学 2008-06-10 Junde Wu , Shangbin Cui

In this paper we study a free boundary problem modeling the growth of solid tumor spheroid. It consists of two elliptic equations describing nutrient diffusion and pressure distribution within tumor, respectively. The new feature is that…

偏微分方程分析 · 数学 2016-12-01 Junde Wu , Fujun Zhou

In this paper we study a free boundary problem for the growth of multi-layer tumors in necrotic phase. The tumor region is strip-like and divided into necrotic region and proliferating region with two free boundaries. The upper free…

偏微分方程分析 · 数学 2019-09-04 Junde Wu

In this paper, we study a free boundary problem modeling solid tumor growth with vasculature which supplies nutrients to the tumor; this is characterized in the Robin boundary condition. It was recently established [Discrete Cont. Dyn.…

偏微分方程分析 · 数学 2020-07-15 Yaodan Huang , Zhengce Zhang , Bei Hu

A two-dimensional free boundary model for the growth of multi-layer tumors has been proposed in [S. Cui, J. Escher: ARMA 191 (2009) 173-193] where the authors derive well-posedness in a functional analytic setting, the stationary solutions…

偏微分方程分析 · 数学 2012-04-12 Martin Kohlmann

In this paper we deal with a free boundary problem modeling the growth of nonnecrotic tumors.The tumor is treated as an incompressible fluid, the tissue elasticity is neglected and no chemical inhibitor species are present. We re-express…

偏微分方程分析 · 数学 2010-03-08 Joachim Escher , Anca-Voichita Matioc

In this paper, we present a rigorous mathematical analysis of a free boundary problem modeling the growth of a vascular solid tumor with a necrotic core. If the vascular system supplies the nutrient concentration $\sigma$ to the tumor at a…

偏微分方程分析 · 数学 2019-09-20 Huijuan Song , Bei Hu , Zejia Wang

We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, King, McElwain, Preziosi, Applied Mathematics Letters, 2003,…

偏微分方程分析 · 数学 2020-06-24 Andrea Genovese de Oliveira , John R. King

In this paper we study a nonlinear free boundary problem on the radial growth of a two-layer solid tumor with a quiescent core. The tumor surface and its inner interface separating the proliferating cells and the quiescent cells are both…

偏微分方程分析 · 数学 2025-01-09 Junde Wu , Hao Xu , Yuehong Zhuang

We study a free boundary problem modeling multi-layer tumor growth with a small time delay $\tau$, representing the time needed for the cell to complete the replication process. The model consists of two elliptic equations which describe…

偏微分方程分析 · 数学 2022-06-22 Wenhua He , Ruixiang Xing , Bei Hu

In this paper, we consider a model with tumor microenvironment involving nutrient density, extracellular matrix and matrix-degrading enzymes, which satisfy a coupled system of PDEs with a free boundary. For this coupled parabolic-hyperbolic…

偏微分方程分析 · 数学 2018-08-24 Rui Li , Bei Hu

In this paper, a free boundary problem modelling the growth of tumor is considered. The model includes two reaction-diffusion equations modelling the diffusion of nutrient and drug in the tumor and three hyperbolic equations describing the…

数值分析 · 数学 2020-01-29 Sakine Esmaili , F. Nasresfahani , M. R. Eslahchi

In this paper, we consider a 3-dimensional free boundary problem modeling tumor growth with the Robin boundary condition. The system involves a positive parameter $\mu$ which reflects the intensity of tumor aggressiveness. Huang, Zhang and…

偏微分方程分析 · 数学 2026-01-23 Junying Chen , Ruixiang Xing

For tumor growth, the morphological instability provides a mechanism for invasion via tumor fingering and fragmentation. This work considers the asymptotic stability of a free boundary tumor model with a periodic supply of external…

偏微分方程分析 · 数学 2021-10-01 Yaodan Huang

Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…

偏微分方程分析 · 数学 2025-04-15 Rafael Granero-Belinchón , Martina Magliocca

In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a…

偏微分方程分析 · 数学 2016-11-14 Junde Wu
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