相关论文: Tumor-immune cell interactions by a fully paraboli…

We show the existence of locally bounded global solutions to the chemotaxis system \[ u_t = \nabla\cdot(D(u)\nabla u) - \nabla\cdot(\frac{u}{v} \nabla v) \] \[ v_t = \Delta v - uv \] with homogeneous Neumann boundary conditions and suitably…

This paper deals with unbounded solutions to the following zero--flux chemotaxis system \begin{equation}\label{ProblemAbstract} \tag{$\Diamond$} \begin{cases} % about u u_t=\nabla \cdot [(u+\alpha)^{m_1-1} \nabla u-\chi u(u+\alpha)^{m_2-2}…

This paper studies the following chemotaxis-fluid system in a two-dimensional bounded domain $\Omega$: \begin{equation*} \begin{cases} n_t + u \cdot \nabla n &= \Delta n - \chi \nabla \cdot \left (n \frac{\nabla c}{c^k} \right ) + r n -…

This paper presents a mathematical model for tumour-immune response interactions in the perspective of immunotherapy by immune checkpoint inhibitors ICIs. The model is of the nonlocal integro-differential Lotka-Volterra type, in which…

Upcoming immunotherapies for cancer treatment rely on the ability of the immune system to detect and eliminate tumors in the body. A highly simplified version of this process can be studied in a Petri dish: starting with a random…

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

This paper investigates the spreading properties of globally defined bounded positive solutions of a chemotaxis system featuring a logistic source and consumption: \[ \left\{ \begin{aligned} &\partial_tu=\Delta u - \chi\nabla\cdot(u\nabla…

In this work we propose and investigate a family of models, which admits as particular cases some well known mathematical models of tumor-immune system interaction, with the additional assumption that the influx of immune system cells may…

This paper deals with the quasilinear parabolic-elliptic chemotaxis system with logistic source and nonlinear production, \begin{equation*} \begin{cases} u_t=\nabla \cdot (D(u) \nabla u) - \nabla \cdot (S(u)\nabla v) + \lambda u - \mu…

Mathematical oncology is a rapidly evolving interdisciplinary field that uses mathematical models to enhance our understanding of cancer dynamics, including tumor growth, metastasis, and treatment response. Tumor-immune interactions play a…

We revisit the following chemotaxis system modeling tumor invasion \begin{equation*} \begin{cases} u_t=\Delta u-\nabla \cdot(u\nabla v),& x\in\Omega, t>0,\\ v_t=\Delta v+wz,& x\in\Omega, t>0,\\ w_t=-wz,& x\in\Omega, t>0,\\ z_t=\Delta z-z+u,…

In this paper we consider the zero-flux chemotaxis-system \begin{equation*} \begin{cases} u_{t}=\Delta u-\nabla \cdot (u \chi(v)\nabla v) & \textrm{in}\quad \Omega\times (0,\infty), \\ 0=\Delta v-v+g(u) & \textrm{in}\quad \Omega\times…

In this paper we consider an optimal control problem arising from a chemotherapeutic drug treatment for tumor cells in a living tissue. The mathematical model for the interaction of chemotherapeutic drug and the normal, tumor and immune…

The paper is concerned with the following chemotaxis system with nonlinear motility functions \begin{equation}\label{0-1}\tag{$\ast$} \begin{cases} u_t=\nabla \cdot (\gamma(v)\nabla u- u\chi(v)\nabla v)+\mu u(1-u), &x\in \Omega, ~~t>0,…

For given total mass $m>0$ we show unique solvability of the stationary chemotaxis-consumption model \[ \begin{cases} 0= \Delta u - \chi \nabla \cdot (\frac{u}{v} \nabla v) \\ 0= \Delta v - uv \\ \int_\Omega u = m \end{cases} \] under…

In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…

In the current paper, we consider the following parabolic-elliptic semilinear Keller-Segel model on $\mathbb{R}^{N}$, \begin{equation*} \begin{cases} u_{t}=\nabla\cdot (\nabla u-\chi u\nabla v)+a u -b u^2, \quad x\in\mathbb{R}^N,\,\, t>0\cr…

In the present work we propose and study a time discrete scheme for the following chemotaxis-consumption model (for any $s\ge 1$), $$ \partial_t u - \Delta u = - \nabla \cdot (u \nabla v), \quad \partial_t v - \Delta v = - u^s v \quad…

This paper deals with a boundary-value problem for a coupled quasilinear chemotaxis--haptotaxis model with nonlinear diffusion $$\left\{\begin{array}{ll} u_t=\nabla\cdot(D(u)\nabla u)-\chi\nabla\cdot(u\nabla v)-\xi \nabla\cdot(u\nabla…

We study a five-compartment mathematical model originally proposed by Kuznetsov et al. (1994) to investigate the effect of nonlinear interactions between tumour and immune cells in the tumour microenvironment, whereby immune cells may…