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We introduce a geometrical extension of the FitzHugh-Nagumo equations describing propagation of electrical impulses in nerve axons. In this extension, the axon is modeled as a warped cylinder, rather than a straight line, as is usually…

偏微分方程分析 · 数学 2021-05-12 Afroditi Talidou , Almut Burchard , Israel Michael Sigal

The use of high-frequency currents in neurostimulation has received increased attention in recent years due to its varied effects on tissues and cells. Nonlinear differential equations are commonly used as models for Neurons, and averaging…

偏微分方程分析 · 数学 2025-12-29 Eduardo Cerpa , Matías Courdurier , Esteban Hernández , Leonel E. Medina , Esteban Paduro

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

斑图形成与孤子 · 物理学 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

The FitzHugh-Nagumo equations are known to admit traveling front solutions in one spatial dimension that are nonlinearly stable. This paper concerns the stability of traveling front solutions propagating on cylindrical surfaces. It is shown…

偏微分方程分析 · 数学 2025-10-10 Afroditi Talidou

This paper is devoted to pulse solutions in FitzHugh--Nagumo systems that are coupled parabolic equations with rapidly periodically oscillating coefficients. In the limit of vanishing periods, there arises a two-scale FitzHugh--Nagumo…

动力系统 · 数学 2017-07-27 Pavel Gurevich , Sina Reichelt

We analyze synchronization of relaxation oscillations in multiple-timescale reaction-diffusion systems. Interpreting synchronization as convergence to frequency-synchronized wave-train solutions, we resolve for the first time the case of…

偏微分方程分析 · 数学 2026-01-12 Montie Avery , Paul Carter , Björn de Rijk , Arnd Scheel

First time in six decades, uncountable infinite exact solutions of FitzHugh-Nagumo model with diffusion have been found. FitzHugh-Nagumo model is a nonlinear dynamical system applicable to neurosciences, chemical kinetics, cell division,…

动力系统 · 数学 2024-07-24 Shahid Sultan Ali Ramji , Eddy Kwessi , Mujahid Abbas

Dynamics of spiral waves in perturbed, e. g. slightly inhomogeneous or subject to a small periodic external force, two-dimensional autowave media can be described asymptotically in terms of Aristotelean dynamics, so that the velocities of…

斑图形成与孤子 · 物理学 2016-12-21 I. V. Biktasheva , A. V. Holden , V. N. Biktashev

The FitzHugh-Nagumo model describing propagation of nerve impulses in axon is given by fast-slow reaction-diffusion equations, with dependence on a parameter $\epsilon$ representing the ratio of time scales. It is well known that for all…

动力系统 · 数学 2016-09-12 Aleksander Czechowski , Piotr Zgliczyński

We study two delay-coupled FitzHugh-Nagumo systems, introducing a mismatch between the delay times, as the simplest representation of interacting neurons. We demonstrate that the presence of delays can cause periodic oscillations which…

适应与自组织系统 · 物理学 2009-11-12 Anastasiia Panchuk , Markus Dahlem , Eckehard Schöll

Propagation of pulses in myelinated fibers may be described by appropriate solutions of spatially discrete FitzHugh-Nagumo systems. In these systems, propagation failure may occur if either the coupling between nodes is not strong enough or…

软凝聚态物质 · 物理学 2009-03-08 A. Carpio , L. L. Bonilla

The FitzHugh-Nagumo equation, originally conceived in neuroscience during the 1960s, became a key model providing a simplified view of excitable neuron cell behavior. Its applicability, however, extends beyond neuroscience into fields like…

斑图形成与孤子 · 物理学 2025-01-08 Daniel Cebrián-Lacasa , Pedro Parra-Rivas , Daniel Ruiz-Reynés , Lendert Gelens

We study the phenomenological model of ensemble of two FitzHugh-Nagumo neuron-like elements with symmetric excitatory couplings. The main advantage of proposed model is the new approach to model of coupling which is implemented by smooth…

We design and study splitting integrators for the temporal discretization of the stochastic FitzHugh--Nagumo system. This system is a model for signal propagation in nerve cells where the voltage variable is solution of a one-dimensional…

数值分析 · 数学 2022-07-22 Charles-Edouard Bréhier , David Cohen , Giuseppe Giordano

We study a system of differential equation simulating transport phenomena in active structured media. The model is a generalization of the McKean s modification of the celebrated FitzHugh--Nagumo system, describing the nerve impulse…

数学物理 · 物理学 2015-06-11 Wojciech Likus , Vsevolod A. Vladimirov

We show the existence of a system size coherence resonance effect for an ensemble of globally coupled excitable systems. Namely, we demonstrate numerically that the regularity in the signal emitted by an ensemble of globally coupled…

凝聚态物理 · 物理学 2007-05-23 Raul Toral , Claudio Mirasso , James D. Gunton

In this paper, we provide a mathematical framework in studying the wave propagation with the annihilation phenomenon in excitable media. We deal with the existence and uniqueness of solutions to a one-dimensional free boundary problem…

偏微分方程分析 · 数学 2021-04-13 Yan-Yu Chen , Hirokazu Ninomiya , Chang-Hong Wu

We study patterns of partial synchronization in a network of FitzHugh-Nagumo oscillators with empirical structural connectivity measured in human subjects. We report the spontaneous occurrence of synchronization phenomena that closely…

适应与自组织系统 · 物理学 2021-02-03 M. Gerster , R. Berner , J. Sawicki , A. Zakharova , A. Škoch , J. Hlinka , K. Lehnertz , E. Schöll

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

神经元与认知 · 定量生物学 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

We introduce discrete and p-adic continuous versions of the FitzHugh-Nagumo system on the one-dimensional p-adic unit ball. We provide criteria for the existence of Turing patterns. We present extensive simulations of some of these systems.…

斑图形成与孤子 · 物理学 2023-11-23 L. F. Chacón-Cortés , C. A. Garcia-Bibiano , W. A. Zúñiga-Galindo
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