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We study the joint dynamics of membrane potential and time since the last spike in a population of integrate-and-fire neurons using a population density framework. This leads to a two-dimensional Fokker-Planck equation that captures the…

无序系统与神经网络 · 物理学 2026-01-01 Luca Falorsi , Gianni V. Vinci , Maurizio Mattia

The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic…

神经元与认知 · 定量生物学 2017-07-20 Moritz Augustin , Josef Ladenbauer , Fabian Baumann , Klaus Obermayer

Despite the huge number of neurons composing a brain network, ongoing activity of local cell assemblies composing cortical columns is intrinsically stochastic. Fluctuations in their instantaneous rate of spike firing $\nu(t)$ scale with the…

神经元与认知 · 定量生物学 2024-04-15 Gianni V. Vinci , Roberto Benzi , Maurizio Mattia

Firing rate fluctuations in neural populations are observed experimentally over multiple time scales, in single neurons, across trials when elicited by stimuli, and across populations. In this work, we examine how firing rate fluctuations…

神经元与认知 · 定量生物学 2026-05-15 Wilten Nicola , Sue Ann Campbell

We study several Fokker-Planck equations arising from a stochastic chemical kinetic system modeling a gene regulatory network in biology. The densities solving the Fokker-Planck equations describe the joint distribution of the messenger RNA…

数值分析 · 数学 2020-09-15 Pierre Degond , Maxime Herda , Sepideh Mirrahimi

We consider an evolving network of a fixed number of nodes. The allocation of edges is a dynamical stochastic process inspired by biological reproduction dynamics, namely by deleting and duplicating existing nodes and their edges. The…

统计力学 · 物理学 2007-09-14 Henrik Jeldtot Jensen

We discuss several models of the dynamics of interacting populations. The models are constructed by nonlinear differential equations and have two sets of parameters: growth rates and coefficients of interaction between populations. We…

适应与自组织系统 · 物理学 2013-07-29 Nikolay K. Vitanov , Zlatinka I. Dimitrova

A novel approach to moment closure problem is used to derive low dimensional laws for the dynamics of the moments of the membrane potential distribution in a population of spiking neurons. Using spectral expansion of the density equation we…

统计力学 · 物理学 2025-07-08 Gianni Valerio Vinci , Roberto Benzi , Maurizio Mattia

Stochastic reaction-diffusion equations are a popular modelling approach for studying interacting populations in a heterogeneous environment under the influence of environmental fluctuations. Although the theoretical basis of alternative…

种群与进化 · 定量生物学 2017-02-16 Ivo Siekmann , Michael Bengfort , Horst Malchow

Providing an analytical treatment to the stochastic feature of neurons' dynamics is one of the current biggest challenges in mathematical biology. The noisy leaky integrate-and-fire model and its associated Fokker-Planck equation are…

神经元与认知 · 定量生物学 2015-12-14 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

We study a system of Fokker-Planck equations recently introduced to describe the temporal evolution of statistical distributions of population densities with predator-prey interactions. At the macroscopic level, the system recovers a…

偏微分方程分析 · 数学 2026-03-11 Giuseppe Toscani , Mattia Zanella

Motivated by the theory of reaction kinetics based on nonequilibrium thermodynamics and the linear stability of driven reaction-diffusion, we apply the Fokker-Planck equation to describe the population dynamics of an ensemble of reactive…

化学物理 · 物理学 2019-07-31 Hongbo Zhao , Martin Z. Bazant

We study a Fokker-Planck equation modelling the firing rates of two interacting populations of neurons. This model arises in computational neuroscience when considering, for example, bistable visual perception problems and is based on a…

偏微分方程分析 · 数学 2011-12-19 José Antonio Carrillo , Stéphane Cordier , Simona Mancini

We propose a model based on coupled multiplicative stochastic processes to understand the dynamics of competing species in an ecosystem. This process can be conveniently described by a Fokker-Planck equation. We provide an analytical…

种群与进化 · 定量生物学 2012-03-13 Simone Pigolotti , Alessandro Flammini , Amos Maritan

Neuronal circuits arise as axons and dendrites extend, navigate, and connect to target cells. Axonal growth, in particular, integrates deterministic guidance from substrate mechanics and geometry with stochastic fluctuations generated by…

生物物理 · 物理学 2025-10-10 Cristian Staii

Finite-size fluctuations in coevolutionary dynamics arise in models of biological as well as of social and economic systems. This brief tutorial review surveys a systematic approach starting from a stochastic process discrete both in time…

种群与进化 · 定量生物学 2019-07-15 Jens Christian Claussen

Neural population equations such as neural mass or field models are widely used to study brain activity on a large scale. However, the relation of these models to the properties of single neurons is unclear. Here we derive an equation for…

神经元与认知 · 定量生物学 2017-04-24 Tilo Schwalger , Moritz Deger , Wulfram Gerstner

Finite-sized populations of spiking elements are fundamental to brain function, but also used in many areas of physics. Here we present a theory of the dynamics of finite-sized populations of spiking units, based on a quasi-renewal…

神经元与认知 · 定量生物学 2015-03-04 Moritz Deger , Tilo Schwalger , Richard Naud , Wulfram Gerstner

The steady-state nucleation rate and flux of composite nucleus at the saddle point is studied by extending the theory of binary nucleation. The Fokker-Planck equation that describes the nucleation flux is derived using the Master equation…

材料科学 · 物理学 2015-06-05 Masao Iwamatsu

In this paper, we consider an opioid epidemic dynamical model with random perturbation that typically describes the interplay between regular prescription use, addictive use, and the process of rehabilitation from addiction and vice-versa.…

最优化与控制 · 数学 2018-06-19 Getachew K. Befekadu , Quanyan Zhu
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