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相关论文: A Hele-Shaw limit without monotonicity

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In this paper we study the "stiff pressure limit" of the porous medium equation, where the initial density is a bounded, integrable function with a sufficient decay at infinity. Our particular model, introduced by Perthame-Quiros-Vazquez,…

偏微分方程分析 · 数学 2015-09-22 Inwon Kim , Norbert Pozar

We consider weak solutions to a problem modeling tumor growth. Under certain conditions on the initial data, solutions can be obtained by passing to the stiff (incompressible) limit in a porous medium type problem with a Lotka-Volterra…

偏微分方程分析 · 数学 2015-12-23 Antoine Mellet , Benoît Perthame , Fernando Quiros

A mathematical model for tissue growth is considered. This model describes the dynamics of the density of cells due to pressure forces and proliferation. It is known that such cell population model converges at the incompressible limit…

偏微分方程分析 · 数学 2017-03-01 Sophie Hecht , Nicolas Vauchelet

We study the "stiff pressure limit" of a nonlinear drift-diffusion equation, where the density is constrained to stay below the maximal value one. The challenge lies in the presence of a drift and the consequent lack of monotonicity in…

偏微分方程分析 · 数学 2017-08-22 Inwon Kim , Norbert Požár , Brent Woodhouse

The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…

偏微分方程分析 · 数学 2015-07-06 Inwon C. Kim , Benoit Perthame , Panagiotis E. Souganidis

Both compressible and incompressible porous medium models are used in the literature to describe the mechanical properties of living tissues. These two classes of models can be related using a stiff pressure law. In the incompressible…

偏微分方程分析 · 数学 2020-06-25 Noemi David , Benoît Perthame

Models of tumor growth, now commonly used, present several levels of complexity, both in terms of the biomedical ingredients and the mathematical description. The simplest ones contain competition for space using purely fluid mechanical…

偏微分方程分析 · 数学 2015-06-12 Benoît Perthame , Fernando Quirós , Juan Luis Vázquez

We investigate a generalized Hele-Shaw equation with a source and drift terms where the density is constrained by an upper-bound density constraint that varies in space and time. By using a generalized porous medium equation approximation,…

偏微分方程分析 · 数学 2022-12-26 Raymond Chu

We study a porous medium equation that models tissue growth in a heterogeneous environment. We show that, in the incompressible limit, solutions converge to those of a weak form of a Hele-Shaw type free boundary problem. To obtain enough…

偏微分方程分析 · 数学 2025-12-11 Anthony Sulak , Olga Turanova

We consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. The model is derived by taking the incompressible limit of porous medium type equations, and the boundary instability of this model was recently studied…

偏微分方程分析 · 数学 2025-05-13 Yu Feng , Qingyou He , Jian-Guo Liu , Zhennan Zhou

In this study, we analyze the behavior of monotone traveling waves of a one-dimensional porous medium equation modeling mechanical properties of living tissues. We are interested in the asymptotics where the pressure, which governs the…

偏微分方程分析 · 数学 2021-08-25 Anne-Laure Dalibard , Gabriela Lopez-Ruiz , Charlotte Perrin

We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…

偏微分方程分析 · 数学 2014-01-14 Benoît Perthame , Fernando Quirós , Min Tang , Nicolas Vauchelet

We consider a (degenerate) cross-diffusion model of tumor growth structured by phenotypic trait. We prove the existence of weak solutions and the incompressible limit as the pressure becomes stiff extending methods recently introduced in…

偏微分方程分析 · 数学 2023-04-04 Noemi David

We investigate the general Porous Medium Equations with drift and source terms that model tumor growth. Incompressible limit of such models has been well-studied in the literature, where convergence of the density and pressure variables are…

偏微分方程分析 · 数学 2024-03-12 Jiajun Tong , Yuming Paul Zhang

In this paper, we consider an age-structured mechanical model for tumor growth. This model takes into account the life-cycle of tumor cells by including an age variable. The underlying process for tumor growth is the same as classical tumor…

偏微分方程分析 · 数学 2026-03-05 Maeve Wildes

In this paper we study a cross-diffusion system whose coefficient matrix is non-symmetric and degenerate. The system arises in the study of tissue growth with autophagy. The existence of a weak solution is established. We also investigate…

偏微分方程分析 · 数学 2021-06-22 Jian-Guo Liu , Xiangsheng Xu

We complete previous results about the incompressible limit of both the $n$-dimensional $(n\geq3)$ compressible Patlak-Keller-Segel (PKS) model and its stationary state. As in previous works, in this limit, we derive the weak form of a…

偏微分方程分析 · 数学 2022-11-22 Qingyou He , Hai-Liang Li , Benoît Perthame

Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…

偏微分方程分析 · 数学 2016-02-17 Benoit Perthame , Nicolas Vauchelet

This paper proposes a model for the growth two interacting populations of cells that do not mix. The dynamics is driven by pressure and cohesion forces on the one hand and proliferation on the other hand. Following earlier works on the…

细胞行为 · 定量生物学 2018-04-12 Alina Chertock , Pierre Degond , Sophie Hecht , Jean-Paul Vincent

We consider the relationship between Hele-Shaw evolution with drift, the porous medium equation with superharmonic drift, and a congested crowd motion model originally proposed by [MRS]- [MRSV]. We first use viscosity solutions to show that…

偏微分方程分析 · 数学 2015-06-15 Damon Alexander , Inwon Kim , Yao Yao
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