相关论文: A Hele-Shaw limit without monotonicity
We consider a model of congestion dynamics with chemotaxis, where the density of cells follows the chemical signal it generates, while observing an incompressibility constraint. We show that when the chemical diffuses slowly and attracts…
This paper investigates the incompressible limit of a system modelling the growth of two cells population. The model describes the dynamics of cell densities, driven by pressure exclusion and cell proliferation. It has been shown that…
The porous medium type reaction-diffusion equation and the Hele-Shaw problem are two free boundary problems linked through the incompressible (Hele-Shaw) limit. We investigate and compare the sharp power concavities of the pressures on…
We study a singular limit of the classical parabolic-elliptic Patlak-Keller-Segel (PKS) model for chemotaxis with non linear diffusion. The main result is the $\Gamma$ convergence of the corresponding energy functional toward the perimeter…
We present a robust computational framework for Hele-Shaw tumor growth with necrotic cores, a problem identified as the incompressible limit of the Porous Media Equation. Simulating this system presents a fundamental challenge: while the…
Nowadays a vast literature is available on the Hele-Shaw or incompressible limit for nonlinear degenerate diffusion equations. This problem has attracted a lot of attention due to its applications to tissue growth and crowd motion modelling…
The link between compressible models of tissue growth and the Hele-Shaw free boundary problem of fluid mechanics has recently attracted a lot of attention. In most of these models, only repulsive forces and advection terms are taken into…
We investigate the large time behavior of an agent based model describing tumor growth. The microscopic model combines short-range repulsion and cell division. As the number of cells increases exponentially in time, the microscopic model is…
Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…
In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…
We consider a model of congestion dynamics with chemotaxis: The density of cells follows a chemical signal it generates, while subject to an incompressibility constraint. The incompressibility constraint results in the formation of patches,…
In this paper, we characterize a degenerate PDE as the gradient flow in the space of nonnegative measures endowed with an optimal transport-growth metric. The PDE of concern, of Hele-Shaw type, was introduced by Perthame et. al. as a…
We study the incompressible limit of the porous medium equation with a reaction term that is non-monotone with respect to the pressure variable. More specifically we consider reaction terms that are either bistable or monostable. We show…
We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…
We revisit the problem of proving the incompressible limit for the compressible porous media equation with Newtonian drift and growth. The question is motivated by models of living tissues development including chemotaxis. We extend the…
We study a Hele-Shaw problem with a mushy region obtained as a Mesa type limit of one phase Stefan problems in exterior domains. We study the convergence, determine some of the qualitative properties and regularity of the unique limiting…
We investigate the tumor boundary instability induced by nutrient consumption and supply based on a Hele-Shaw model derived from taking the incompressible limit of a cell density model. We analyze the boundary stability/instability in two…
We study the linear stability of the displacement of three Stokes fluids with constant viscosity in a porous medium when the middle fluid is contained in a bounded region. We use the Hele-Shaw model. The eigenfunctions of the stability…
We study the dynamics of compressible fluids in rotating heterogeneous porous media. The fluid flow is of {F}orchheimer-type and is subject to a mixed mass and volumetric flux boundary condition. The governing equations are reduced to a…
In this work we study a tissue growth model with applications to tumour growth. The model is based on that of Perthame, Quir\'os, and V\'azquez proposed in 2014 but incorporates the advective effects caused, for instance, by the presence of…