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We investigate a broad family of non weakly reversible stochastically modeled reaction networks (CRN), by looking at their steady-state distributions. Most known results on stationary distributions assume weak reversibility and zero…

概率论 · 数学 2023-02-20 Linard Hoessly , Christian Mazza

Exact results for product-form stationary distributions of Markov chains are of interest in different fields. In stochastic reaction networks (CRNs), stationary distributions are mostly known in special cases where they are of product-form.…

概率论 · 数学 2021-12-07 Beatriz Pascual-Escudero , Linard Hoessly

Reaction networks have become a major modelling framework in the biological sciences from epidemiology and population biology to genetics and cellular biology. In recent years, much progress has been made on stochastic reaction networks…

概率论 · 数学 2025-08-14 Linard Hoessly , Carsten Wiuf , Panqiu Xia

Continuous-time Markov chains are frequently used as stochastic models for chemical reaction networks, especially in the growing field of systems biology. A fundamental problem for these Stochastic Chemical Reaction Networks (SCRNs) is to…

In many applications, for example when computing statistics of fast subsystems in a multiscale setting, we wish to find the stationary distributions of systems of continuous time Markov chains. Here we present a class of models that appears…

概率论 · 数学 2016-09-20 David F. Anderson , Simon L. Cotter

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

分子网络 · 定量生物学 2019-07-11 Ozan Kahramanoğulları

Reaction networks are widely used models to describe biochemical processes. Stochastic fluctuations in the counts of biological macromolecules have amplified consequences due to their small population sizes. This makes it necessary to favor…

概率论 · 数学 2022-02-28 Daniele Cappelletti , Badal Joshi

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

动力系统 · 数学 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz

Stochastic chemical reaction networks (CRNs) are complex systems which combine the features of concurrent transformation of multiple variables in each elementary reaction event, and nonlinear relations between states and their rates of…

化学物理 · 物理学 2017-12-06 Eric Smith , Supriya Krishnamurthy

In this paper, we abstract a kind of stochastic processes from evolving processes of growing networks, this process is called growing network Markov chains. Thus the existence and the formulas of degree distribution are transformed to the…

数学物理 · 物理学 2015-05-13 Zhenting Hou , Xiangxing Kong , Dinghua Shi , Guanrong Chen , Qinggui Zhao

The asymptotic properties of some Markov processes associated to stochastic chemical reaction networks (CRNs) driven by the kinetics of the law of mass action are analyzed. The scaling regime introduced in the paper assumes that the norm of…

概率论 · 数学 2025-12-18 Lucie Laurence , Philippe Robert

Analysis of large continuous-time stochastic systems is a computationally intensive task. In this work we focus on population models arising from chemical reaction networks (CRNs), which play a fundamental role in analysis and design of…

系统与控制 · 计算机科学 2019-05-27 Milan Češka , Jan Křetínský

We study stationary distributions in the context of stochastic reaction networks. In particular, we are interested in complex balanced reaction networks and reduction of such networks by assuming a set of species (called non-interacting…

概率论 · 数学 2024-02-06 Linard Hoessly , Carsten Wiuf , Panqiu Xia

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

概率论 · 数学 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

Stochastic Chemical Reaction Networks are continuous time Markov chain models that describe the time evolution of the molecular counts of species interacting stochastically via discrete reactions. Such models are ubiquitous in systems and…

定量方法 · 定量生物学 2024-02-01 Theodore W. Grunberg , Domitilla Del Vecchio

We consider stochastic reaction networks modeled by continuous-time Markov chains. Such reaction networks often contain many reactions, potentially occurring at different time scales, and have unknown parameters (kinetic rates, total…

概率论 · 数学 2023-02-20 Linard Hoessly , Carsten Wiuf

We consider steady states of dynamics that have an underlying network structure. We study how a steady state responds to small perturbations in the network parameters and how this sensitivity is connected to the network structure. We…

分子网络 · 定量生物学 2023-03-20 Robin Chemnitz

Stochastic reaction networks are dynamical models of biochemical reaction systems and form a particular class of continuous-time Markov chains on $\mathbb{N}^n$. Here we provide a fundamental characterisation that connects structural…

概率论 · 数学 2018-05-22 Daniele Cappelletti , Carsten Wiuf

The paper deals with non-linear Poisson neuron network models with bounded memory dynamics, that can include both Hebbian learning mechanisms and refractory periods. The state of a network is described by the times elapsed since its neurons…

概率论 · 数学 2012-06-21 Konstantin Borovkov , Geoffrey Decrouez , Matthieu Gilson

Chemical reaction networks describe interactions between biochemical species. Once an underlying reaction network is given for a biochemical system, the system dynamics can be modelled with various mathematical frameworks such as continuous…

概率论 · 数学 2023-06-22 German Enciso , Radek Erban , Jinsu Kim
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