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This paper treats a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis. The evolution of the tumor fraction is governed by a variational inequality corresponding to a double obstacle…

最优化与控制 · 数学 2021-04-21 Pierluigi Colli , Andrea Signori , Jürgen Sprekels

This paper is intended to tackle the control problem associated with an extended phase field system of Cahn-Hilliard type that is related to a tumor growth model. This system has been investigated in previous contributions from the…

偏微分方程分析 · 数学 2018-11-26 Andrea Signori

This paper concerns a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis with possibly singular potentials, where the control and state variables are nonlinearly coupled. First, we…

最优化与控制 · 数学 2023-06-06 Pierluigi Colli , Andrea Signori , Jürgen Sprekels

In this paper, we study the optimal control of a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. Both the cases…

最优化与控制 · 数学 2026-03-17 Pierluigi Colli , Elisabetta Rocca , Jürgen Sprekels

This paper is concerned with a distributed optimal control problem for a nonlocal phase field model of Cahn-Hilliard type, which is a nonlocal version of a model for two-species phase segregation on an atomic lattice under the presence of…

偏微分方程分析 · 数学 2016-07-08 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

最优化与控制 · 数学 2021-10-12 Matthias Ebenbeck , Patrik Knopf

The paper arXiv:1804.11290 contains well-posedness and regularity results for a system of evolutionary operator equations having the structure of a Cahn-Hilliard system. The operators appearing in the system equations were fractional…

偏微分方程分析 · 数学 2018-12-17 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

This paper treats a distributed optimal control problem for a tumor growth model of viscous Cahn--Hilliard type. The evolution of the tumor fraction is governed by a thermodynamic force induced by a double-well potential of logarithmic…

最优化与控制 · 数学 2023-06-14 Jürgen Sprekels , Fredi Tröltzsch

This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…

偏微分方程分析 · 数学 2024-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We consider a particular phase field system which physical context is that of tumor growth dynamics. The model we deal with consists of a Cahn-Hilliard type equation governing the evolution of the phase variable which takes into account the…

偏微分方程分析 · 数学 2019-08-30 Andrea Signori

In this paper, we investigate a distributed optimal control problem for a convective viscous Cahn-Hilliard system with dynamic boundary conditions. Such systems govern phase separation processes between two phases taking place in an…

偏微分方程分析 · 数学 2017-09-13 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

In this paper, we address an optimal distributed control problem for a non-local model of phase-field type, describing the evolution of tumour cells in presence of a nutrient. The model couples a non-local and viscous Cahn-Hilliard equation…

偏微分方程分析 · 数学 2023-10-25 Matteo Fornoni

We study a stochastic phase-field model for tumor growth dynamics coupling a stochastic Cahn-Hilliard equation for the tumor phase parameter with a stochastic reaction-diffusion equation governing the nutrient proportion. We prove strong…

偏微分方程分析 · 数学 2021-01-19 Carlo Orrieri , Elisabetta Rocca , Luca Scarpa

A distributed optimal control problem for a phase field system which physical context is that of tumor growth is discussed. The system we are going to take into account consists of a Cahn-Hilliard equation for the phase variable (relative…

偏微分方程分析 · 数学 2021-01-20 Andrea Signori

We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…

偏微分方程分析 · 数学 2024-07-29 Matteo Fornoni

We study a Cahn-Hilliard-Darcy system with mass sources, which can be considered as a basic, though simplified, diffuse interface model for the evolution of tumor growth. This system is equipped with an impermeability condition for the…

最优化与控制 · 数学 2024-08-20 Marco Abatangelo , Cecilia Cavaterra , Maurizio Grasselli , Hao Wu

In this paper, we study an optimal control problem for a two-dimensional Cahn-Hilliard-Darcy system with mass sources that arises in the modeling of tumor growth. The aim is to monitor the tumor fraction in a finite time interval in such a…

偏微分方程分析 · 数学 2023-07-28 Juergen Sprekels , Hao Wu

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

最优化与控制 · 数学 2021-10-12 Matthias Ebenbeck , Patrik Knopf

A distributed optimal control problem for a diffuse interface model, which physical context is that of tumour growth dynamics, is addressed. The system we deal with comprises a Cahn--Hilliard equation for the tumour fraction coupled with a…

偏微分方程分析 · 数学 2021-01-20 Andrea Signori

We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…

偏微分方程分析 · 数学 2017-05-04 Harald Garcke , Kei Fong Lam
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