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相关论文: On a diffuse interface model of tumor growth

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We consider a diffuse interface model that describes the macro- and micro-phase separation processes of a polymer mixture. The resulting system consists of a Cahn-Hilliard equation and a Cahn-Hilliard-Oono type equation endowed with the…

偏微分方程分析 · 数学 2024-05-01 Bohan Ouyang

We consider the initial-boundary value problem of a thermodynamically consistent diffuse interface model for incompressible two-phase flows with unmatched densities in a bounded domain $\Omega\subset\mathbb{R}^3$. Our first aim is to study…

偏微分方程分析 · 数学 2026-03-30 Harald Garcke , Maoyin Lv , Hao Wu

We consider weak solutions to a problem modeling tumor growth. Under certain conditions on the initial data, solutions can be obtained by passing to the stiff (incompressible) limit in a porous medium type problem with a Lotka-Volterra…

偏微分方程分析 · 数学 2015-12-23 Antoine Mellet , Benoît Perthame , Fernando Quiros

We study a thermodynamically consistent diffuse interface model that describes the motion of a two-phase flow of two viscous incompressible Newtonian fluids with unmatched densities and a soluble surfactant in a bounded domain of two or…

偏微分方程分析 · 数学 2026-01-13 Bohan Ouyang , Maurizio Grasselli , Hao Wu

We study a diffuse-interface model that describes the dynamics of two-phase incompressible flows driven by the thermo-induced Marangoni effect. The hydrodynamic system consists of the Navier-Stokes equations for the fluid velocity, the…

偏微分方程分析 · 数学 2026-05-26 Lingxi Chen , Hao Wu

In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…

偏微分方程分析 · 数学 2026-02-16 Pierluigi Colli , Elisabetta Rocca , Jürgen Sprekels

This article is devoted to the derivation and analysis of a system of partial differential equations modeling a diffuse interface flow of two Newtonian incompressible magnetic fluids. The system consists of the incompressible Navier-Stokes…

偏微分方程分析 · 数学 2020-04-22 Martin Kalousek , Sourav Mitra , Anja Schlömerkemper

We present a robust computational framework for Hele-Shaw tumor growth with necrotic cores, a problem identified as the incompressible limit of the Porous Media Equation. Simulating this system presents a fundamental challenge: while the…

数值分析 · 数学 2026-02-16 Yu Feng , Shuo Ling , Wenjun Ying , Zhennan Zhou

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

We investigate a new diffuse-interface model that describes creeping two-phase flows (i.e., flows exhibiting a low Reynolds number), especially flows that permeate a porous medium. The system of equations consists of a Brinkman equation for…

偏微分方程分析 · 数学 2025-09-15 Pierluigi Colli , Patrik Knopf , Giulio Schimperna , Andrea Signori

We consider a local Cahn-Hilliard-type model for tumor growth as well as a nonlocal model where, compared to the local system, the Laplacian in the equation for the chemical potential is replaced by a nonlocal operator. The latter is…

偏微分方程分析 · 数学 2024-02-22 Christoph Hurm , Maximilian Moser

The Cahn-Hilliard equation is the most common model to describe phase separation processes of a mixture of two components. For a better description of short-range interactions of the material with the solid wall, various dynamic boundary…

偏微分方程分析 · 数学 2020-10-20 Harald Garcke , Patrik Knopf

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

偏微分方程分析 · 数学 2013-06-11 Martin Kohlmann

The evolution of two partially miscible, nonhomogeneous, incompressible viscous fluids of non-Newtonian type, can be governed by the Navier-Stokes-Cahn-Hilliard system. In the present work, we prove the global existence of weak solutions…

偏微分方程分析 · 数学 2025-12-25 Fang Li , Duan Xingyu , Guo Zhenhua

We prove existence of weak solutions for a diffuse interface model for the flow of two viscous incompressible Newtonian fluids with different densities in a bounded domain in two and three space dimensions. In contrast to previous works, we…

偏微分方程分析 · 数学 2019-11-21 Helmut Abels , Yutaka Terasawa

This paper is concerned with a phase field system of Cahn-Hilliard type that is related to a tumor growth model and consists of three equations in terms of the variables order parameter, chemical potential and nutrient concentration. This…

偏微分方程分析 · 数学 2015-03-04 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Jürgen Sprekels

We present a model for cell growth, division and packing under soft constraints that arise from the deformability of the cells as well as of a membrane that encloses them. Our treatment falls within the framework of diffuse interface…

细胞行为 · 定量生物学 2019-01-09 J. Jiang , K. Garikipati , S. Rudraraju

We study the sharp interface limit of a non-mass-conserving Cahn--Hilliard--Darcy system with the weak compactness method developed in Chen (J. Differential Geometry, 1996). The source term present in the Cahn--Hilliard component is a…

偏微分方程分析 · 数学 2019-02-22 Kei Fong Lam

We show short-time well-posedness of a diffuse interface model describing the flow of a fluid through a deformable porous medium consisting of two phases. The system non-linearly couples Biot's equations for poroelasticity, including…

偏微分方程分析 · 数学 2026-05-01 Helmut Abels , Jonas Haselböck

We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…

偏微分方程分析 · 数学 2014-01-14 Benoît Perthame , Fernando Quirós , Min Tang , Nicolas Vauchelet