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相关论文: On a diffuse interface model of tumor growth

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The Cahn-Hilliard model with reaction terms can lead to situations in which no coarsening is taking place and, in contrast, growth and division of droplets occur which all do not grow larger than a certain size. This phenomenon has been…

偏微分方程分析 · 数学 2025-11-07 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

We consider a (degenerate) cross-diffusion model of tumor growth structured by phenotypic trait. We prove the existence of weak solutions and the incompressible limit as the pressure becomes stiff extending methods recently introduced in…

偏微分方程分析 · 数学 2023-04-04 Noemi David

In this paper, the authors study the distributed optimal control of a system of three evolutionary equations involving fractional powers of three selfadjoint, monotone, unbounded linear operators having compact resolvents. The system is a…

最优化与控制 · 数学 2019-07-25 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

We analyze a diffuse interface model that describes the dynamics of incompressible viscous two-phase flows, incorporating mechanisms such as chemotaxis, active transport, and long-range interactions of Oono's type. The evolution system…

偏微分方程分析 · 数学 2025-10-28 Jingning He , Hao Wu

In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for…

偏微分方程分析 · 数学 2025-08-27 Jeffrey Kuan , Konstantina Trivisa

We study an initial-boundary value problem for the incompressible Navier-Stokes-Cahn-Hilliard system with non-constant density proposed by Abels, Garcke and Gr\"{u}n in 2012. This model arises in the diffuse interface theory for binary…

偏微分方程分析 · 数学 2023-02-21 Helmut Abels , Harald Garcke , Andrea Giorgini

We consider very weak solutions of the Cauchy problem for the porous medium equation on Cartan-Hadamard manifolds, that are assumed to satisfy general curvature bounds and to be stochastically complete. We identify a class of initial data…

偏微分方程分析 · 数学 2022-02-18 Gabriele Grillo , Matteo Muratori , Fabio Punzo

We consider the inverse problem of parameter estimation in a diffuse interface model for tumour growth. The model consists of a fourth-order Cahn-Hilliard system and contains three phenomenological parameters: the tumour proliferation rate,…

数值分析 · 数学 2019-05-10 Christian Kahle , Kei Fong Lam , Jonas Latz , Elisabeth Ullmann

In this paper we study the "stiff pressure limit" of the porous medium equation, where the initial density is a bounded, integrable function with a sufficient decay at infinity. Our particular model, introduced by Perthame-Quiros-Vazquez,…

偏微分方程分析 · 数学 2015-09-22 Inwon Kim , Norbert Pozar

We study an initial-boundary value problem (IBVP) for a coupled Cahn-Hilliard-Hele-Shaw system that models tumor growth. For large initial data with finite energy, we prove global (local resp.) existence, uniqueness, higher order spatial…

偏微分方程分析 · 数学 2012-05-31 John Lowengrub , Edriss S. Titi , Kun Zhao

We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…

偏微分方程分析 · 数学 2022-10-14 Samiha Belmor

We show existence and uniqueness of very weak solutions of the Cauchy problem for the porous medium equation on Cartan-Hadamard manifolds satisfying suitable lower bounds on Ricci curvature, with initial data that can grow at infinity at a…

偏微分方程分析 · 数学 2018-06-12 Gabriele Grillo , Matteo Muratori , Fabio Punzo

We consider a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects which is introduced in [2]. It is comprised of phase-field equation to describe tumor growth, which is coupled to a…

偏微分方程分析 · 数学 2020-10-22 Tania Biswas , Elisabetta Rocca

We present a diffuse-interface model for the solid-state dewetting problem with anisotropic surface energies in ${\mathbb R}^d$ for $d\in\{2,3\}$. The introduced model consists of the anisotropic Cahn--Hilliard equation, with either a…

偏微分方程分析 · 数学 2023-02-15 Harald Garcke , Patrik Knopf , Robert Nürnberg , Quan Zhao

In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…

偏微分方程分析 · 数学 2021-08-31 Xu'an Dou , Jian-Guo Liu , Zhennan Zhou

We consider a diffuse interface model for an incompressible isothermal mixture of two viscous Newtonian fluids with different densities in a bounded domain in two or three space dimensions. The model is the nonlocal version of the one…

偏微分方程分析 · 数学 2015-06-01 Sergio Frigeri

We investigate a diffuse-interface model that describes the dynamics of incompressible two-phase viscous flows with surfactant. The resulting system of partial differential equations consists of a sixth-order Cahn-Hilliard equation for the…

偏微分方程分析 · 数学 2023-07-28 Andrea Di Primio , Maurizio Grasselli , Hao Wu

We study the asymptotic limit of diffused surface energy in the van der Waals--Cahn--Hillard theory when an advection term is added and the energy is uniformly bounded. We prove that the limit interface is an integral varifold and the…

偏微分方程分析 · 数学 2020-10-12 Yoshihiro Tonegawa , Yuki Tsukamoto

We study a time-fractional Fisher-KPP equation involving a Riemann-Liouville fractional derivative acting on the diffusion term, as derived by Angstmann and Henry (Entropy, 22:1035, 2020). The model captures memory effects in diffusive…

偏微分方程分析 · 数学 2025-11-10 Marvin Fritz , Nikos I. Kavallaris

We rigorously prove the convergence of weak solutions to a model for lipid raft formation in cell membranes which was recently proposed by Garcke et al. to weak (varifold) solutions of the corresponding sharp-interface problem for a…

偏微分方程分析 · 数学 2019-02-05 Helmut Abels , Johannes Kampmann