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相关论文: On persistence and cascade decompositions of chemi…

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This paper develops the concept of decomposition for chemical reaction networks, based on which a network decomposition technique is proposed to capture the stability of large-scale networks characterized by a high number of species, high…

动力系统 · 数学 2021-02-23 Yafei Lu , Chuanhou Gao , Denis Dochain

For dynamical systems arising from chemical reaction networks, persistence is the property that each species concentration remains positively bounded away from zero, as long as species concentrations were all positive in the beginning. We…

动力系统 · 数学 2016-07-29 Michael Marcondes de Freitas , Elisenda Feliu , Carsten Wiuf

Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

分子网络 · 定量生物学 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

In living cells, chemical reactions form a complex network. Complicated dynamics arising from such networks are the origins of biological functions. We propose a novel mathematical method to analyze bifurcation behaviors of a reaction…

分子网络 · 定量生物学 2018-08-08 Takashi Okada , Je-Chiang Tsai , Atsushi Mochizuki

We consider the question whether a chemical reaction network preserves the number and stability of its positive steady states upon inclusion of inflow and outflow reactions. Often a model of a reaction network is presented without inflows…

分子网络 · 定量生物学 2019-12-11 Daniele Cappelletti , Elisenda Feliu , Carsten Wiuf

We describe a large class of chemical reaction networks, those endowed with a subtle structural property called concordance. We show that the class of concordant networks coincides precisely with the class of networks which, when taken with…

分子网络 · 定量生物学 2011-09-15 Guy Shinar , Martin Feinberg

Autocatalytic chemical reaction networks can collectively replicate or maintain their constituents despite degradation reactions only above a certain threshold, which we refer to as the decay threshold. When the chemical network has a…

分子网络 · 定量生物学 2025-11-17 Armand Despons , Jérémie Unterberger , David Lacoste

Under suitable assumptions, the dynamic behaviour of a chemical reaction network is governed by an autonomous set of polynomial ordinary differential equations over continuous variables representing the concentrations of the reactant…

动力系统 · 数学 2014-07-15 Matthew D. Johnston , David Siegel

This paper concerns the long-term behavior of population systems, and in particular of chemical reaction systems, modeled by deterministic mass-action kinetics. We approach two important open problems in the field of Chemical Reaction…

动力系统 · 数学 2012-03-21 Casian Pantea

In this paper, we propose a novel technique, referred to as the Lyapunov Function PDEs technique, to diagnose persistence of chemical reaction networks with mass-action kinetics. The technique allows that every network is attached to a…

动力系统 · 数学 2019-02-01 Xiaoyu Zhang , Zhou Fang , Chuanhou Gao

Robustness of biochemical systems has become one of the central questions in systems biology although it is notoriously difficult to formally capture its multifaceted nature. Maintenance of normal system function depends not only on the…

分子网络 · 定量生物学 2012-03-28 Jost Neigenfind , Sergio Grimbs , Zoran Nikoloski

Persistency is the property, for differential equations in $\R^n$, that solutions starting in the positive orthant do not approach the boundary. For chemical reactions and population models, this translates into the non-extinction property:…

分子网络 · 定量生物学 2007-05-23 David Angeli , Patrick De Leenheer , Eduardo Sontag

For the networks that are linear conjugate to complex balanced systems, the delayed version may include two classes of networks: one class is still linear conjugate to the delayed complex balanced network, the other is not. In this paper,…

动力系统 · 数学 2022-04-07 Xiaoyu Zhang , Chuanhou Gao , Denis Dochain

We consider local bifurcations of equilibria in dynamical systems arising from chemical reaction networks with mass action kinetics. In particular, given any mass action network admitting a local bifurcation of equilibria, assuming only a…

动力系统 · 数学 2025-05-20 Murad Banaji , Balázs Boros , Josef Hofbauer

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

分子网络 · 定量生物学 2012-04-26 Guy Shinar , Martin Feinberg

This paper presents a stability test for a class of interconnected nonlinear systems motivated by biochemical reaction networks. One of the main results determines global asymptotic stability of the network from the diagonal stability of a…

定量方法 · 定量生物学 2007-05-23 Murat Arcak , Eduardo D. Sontag

We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction rate constants. This result holds for closed systems without…

分子网络 · 定量生物学 2015-03-19 Santiago Akle , Onkar Dalal , Ronan M. T. Fleming , Michael Saunders , Nicole Taheri , Yinyu Ye

In this paper, we derive two sufficient conditions to diagnose the persistence of two classes of delayed complex balanced chemical reaction network systems equipped with mass-action kinetics. One class is identified by $\dim…

动力系统 · 数学 2019-08-23 Xiaoyu Zhang , Chuanhou Gao

There is a commonality among contagious diseases, tweets, urban crimes, nuclear reactions, and neuronal firings that past events facilitate the future occurrence of events. The spread of events has been extensively studied such that the…

物理与社会 · 物理学 2016-09-16 Tomokatsu Onaga , Shigeru Shinomoto

The persistence conjecture is a long-standing open problem in chemical reaction network theory. It concerns the behavior of solutions to coupled ODE systems that arise from applying mass-action kinetics to a network of chemical reactions.…

动力系统 · 数学 2014-10-07 Abhishek Deshpande , Manoj Gopalkrishnan
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