相关论文: Wavespeed selection and interstitial gap formation…
In this manuscript, we prove the existence of slow and fast traveling wave solutions in the original Gatenby--Gawlinski model. We prove the existence of a slow traveling wave solution with an interstitial gap. This interstitial gap has…
The Fisher-KPP model, and generalisations thereof, is a simple reaction-diffusion models of biological invasion that assumes individuals in the population undergo linear diffusion with diffusivity $D$, and logistic proliferation with rate…
Single-species reaction-diffusion equations, such as the Fisher-KPP and Porous-Fisher equations, support travelling wave solutions that are often interpreted as simple mathematical models of biological invasion. Such travelling wave…
We study travelling-wave solutions for a reaction-diffusion system arising as a model for host-tissue degradation by bacteria. This system consists of a parabolic equation coupled with an ordinary differential equation. For large values of…
In this paper, we carry out a travelling-wave analysis of a model of tumour invasion with degenerate, cross-dependent diffusion. We consider two types of invasive fronts of tumour tissue into extracellular matrix (ECM), which represents…
We consider a minimal go-or-grow model of cell invasion, whereby cells can either proliferate, following logistic growth, or move, via linear diffusion, and phenotypic switching between these two states is density-dependent. Formal analysis…
Biological invasion, whereby populations of motile and proliferative individuals lead to moving fronts that invade into vacant regions, are routinely studied using partial differential equation (PDE) models based upon the classical…
We address the propagation into an unstable state of a localised disturbance in a forward-backward diffusion pseudo-parabolic equation. Three asymptotic regimes are distinguished as t tends to infinity, the first being a regime ahead of the…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…
We consider a Fisher-KPP equation with density-dependent diffusion and advection, arising from a chemotaxis-growth model. We study its behavior as a small parameter, related to the thickness of a diffuse interface, tends to zero. We…
Continuum mathematical models for collective cell motion normally involve reaction-diffusion equations, such as the Fisher-KPP equation, with a linear diffusion term to describe cell motility and a logistic term to describe cell…
The acid-mediated tumor invasion hypothesis proposes that altered glucose metabolism exhibited by the vast majority of tumors leads to increased acid (H+ ion) production which subsequently facilitates tumor invasion [1-3]. The…
We consider a coupled reaction-advection-diffusion system based on the Fisher-KPP and Burgers equations. These equations serve as a one-dimensional version of a model for a reacting fluid in which the arising density differences induce a…
We analyse a novel mathematical model of malignant invasion which takes the form of a two-phase moving boundary problem describing the invasion of a population of malignant cells into a population of background tissue, such as skin. Cells…
We show that propagation speeds in invasion processes modeled by reaction-diffusion systems are determined by marginal spectral stability conditions, as predicted by the marginal stability conjecture. This conjecture was recently settled in…
We consider a class of cooperative reaction-diffusion systems with free boundaries in one space dimension, where the diffusion terms are nonlocal, given by integral operators involving suitable kernel functions, and they are allowed not to…
We investigate a recently proposed cross-diffusion system modelling the growth of gliobastoma taking into account size exclusion both in the migration and proliferation process. In addition to degenerate nonlinear cross-diffusion the model…
Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…
We consider a reaction-diffusion process with retardation. The particles, immersed in traps initially, remain inactive until another particle is annihilated spontaneously with a rate $\lambda$ at a certain point $\vec x$. In that case the…
Reaction-diffusion models are often used to describe biological invasion, where populations of individuals that undergo random motility and proliferation lead to moving fronts. Many models of biological invasion are extensions of the…