相关论文: Global weak solutions and asymptotics of a singula…
The global dynamics and regularity of parabolic-hyperbolic systems is an interesting topic in PDEs due to the coupling of competing dissipation and hyperbolic effects. This paper is concerned with the Cauchy problem of a…
Motivated by an ongoing collaboration with clinical oncologists and pathologists, we develop a hybrid partial differential equation--ordinary differential equation (PDE--ODE) framework that captures (i) competition between susceptible and…
In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma, which includes an anisotropic nonlinear diffusion term with a diffusion velocity increasing with respect to vasculature. First, we prove the existence of…
In this paper, we investigate the optimal large-time behavior of the global solution to a singular chemotaxis system in the whole space $\mathbb{R}^d$ with $d=2,3$. Assuming that the initial data is sufficiently close to an equilibrium…
We consider an evolutionary PDE system coupling the Cahn-Hilliard equation with singular potential, mass source and transport effects, to a Brinkman-type relation for the macroscopic velocity field and to a further equation describing the…
This paper studies the following system of differential equations modeling tumor angiogenesis in a bounded smooth domain $\Omega \subset \mathbb{R}^N$ ($N=1,2$): $$\label{0} \left\{\begin{array}{ll} p_t=\Delta p-\nabla\cdotp…
We analyze a diffuse interface model that describes the dynamics of incompressible two-phase flows with chemotaxis effect. The PDE system couples a Navier-Stokes equation for the fluid velocity, a convective Cahn-Hilliard equation for the…
We study a diffuse interface model that describes the dynamics of incompressible two-phase flows with chemotaxis effects. This model also takes into account some significant mechanisms such as active transport and nonlocal interactions of…
In the present work, we investigate a model of the invasion of healthy tissue by cancer cells which is described by a system of nonlinear PDEs consisting of a cross-diffusion-reaction equation and two additional nonlinear ordinary…
We investigate a hydrodynamic system of Navier--Stokes/Cahn--Hilliard type, which describes the motion of a two-phase flow of two incompressible fluids with unmatched densities coupled with a soluble chemical species. Derived from Onsager's…
We analyze a Navier-Stokes-Cahn-Hilliard model for viscous incompressible two-phase flows where the mechanisms of chemotaxis, active transport and reaction are taken into account. The evolution system couples the Navier-Stokes equations for…
We study the dynamics of systems consisting of two spatially segregated ODE compartments coupled through a one-dimensional bulk diffusion field. For this coupled PDE-ODE system, we first employ a multi-scale asymptotic expansion to derive…
We propose and study a strongly coupled PDE-ODE system with tissue-dependent degenerate diffusion and haptotaxis that can serve as a model prototype for cancer cell invasion through the extracellular matrix. We prove the global existence of…
We analyze a diffuse interface model that couples a viscous Cahn-Hilliard equation for the phase variable with a diffusion-reaction equation for the nutrient concentration. The system under consideration also takes into account some…
We propose a PDE-ODE model for tissue regeneration, obtained by parabolic upscaling from kinetic transport equations written for the mesoscopic densities of mesenchymal stem cells and chondrocytes which evolve in an artificial scaffold…
In this paper, we study a semilinear parabolic PDE system which describes the interaction of normal cells, tumor cells, immune cells, with a chemotherapeutic drug. The model extends the previous model with incorporating strong Allee affects…
The present work proceeds to consider the convergence of the solutions to the following doubly degenerate chemotaxis-consumption system \begin{align*} \left\{ \begin{array}{r@{\,}l@{\quad}l@{\,}c} &u_{t}=\nabla\cdot\big(u^{m-1}v\nabla…
In this paper, we investigate an initial-boundary value problem for a chemotaxis-fluid system in a general bounded regular domain $\Omega \subset \mathbb{R}^N$ ($N\in\{2,3\}$), not necessarily being convex. Thanks to the elementary lemma…
Convergence of solutions to a partially diffusive chemotaxis system with indirect signal production and phenotype switching is shown in a two-dimensional setting when the switching rate increases to infinity, thereby providing a rigorous…
Flow of molecular gas into a complex vacuum system is investigated by a lumped parameter model to estimate the time evolution of gas pressure $p_g$, which for the first time takes into account the realistic effect of time-delay arising due…