相关论文: Free boundary problems for Tumor Growth: a Viscosi…

We consider a model of congestion dynamics with chemotaxis, where the density of cells follows the chemical signal it generates, while observing an incompressibility constraint. We show that when the chemical diffuses slowly and attracts…

This is the sequel of the recent work (Du, Huang, Pu, Commun. Math. Phys, 2023, doi: 10.1007/s00220-023-04651-7) on axially symmetric gravity water waves with general vorticities, which has investigated the singular wave profile of the free…

We derive sharp regularity for viscosity solutions of an inhomogeneous infinity Laplace equation across the free boundary, when the right hand side does not change sign and satisfies a certain growth condition. We prove geometric regularity…

We consider the homogenization of the Hele-Shaw problem in periodic media that are inhomogeneous both in space and time. After extending the theory of viscosity solutions into this context, we show that the solutions of the inhomogeneous…

We introduce a notion of viscosity solutions for a nonlinear degenerate diffusion equation with a drift potential. We show that our notion of solutions coincide with the weak solutions defined via integration by parts. As an application of…

In this paper, we investigate the tumor instability by employing both analytical and numerical techniques to validate previous results and extend the analytical findings presented in a prior study by Feng et al 2023. Building upon the…

We study a Hele-Shaw problem with a mushy region obtained as a Mesa type limit of one phase Stefan problems in exterior domains. We study the convergence, determine some of the qualitative properties and regularity of the unique limiting…

We study an initial-boundary value problem (IBVP) for a coupled Cahn-Hilliard-Hele-Shaw system that models tumor growth. For large initial data with finite energy, we prove global (local resp.) existence, uniqueness, higher order spatial…

We construct viscosity solutions to the nonlinear evolution equation \eqref{p} below which generalizes the motion of level sets by mean curvature (the latter corresponds to the case $p = 1$) using the regularization scheme as in \cite{ES1}…

We consider the free boundary incompressible porous media equation which describes the dynamics of a density transported by a Darcy flow in the field of gravity, with a free boundary between the fluid region and the dry region above it. For…

In this work we study a tissue growth model with applications to tumour growth. The model is based on that of Perthame, Quir\'os, and V\'azquez proposed in 2014 but incorporates the advective effects caused, for instance, by the presence of…

In this paper, we study the dynamics of a two-dimensional viscous fluid evolving through a porous medium or a Hele-Shaw cell, driven by gravity and surface tension. A key feature of this study is that the fluid is confined within a vessel…

We discuss the sharp interface limit of a diffuse interface model for a coupled Cahn-Hilliard--Darcy system that models tumor growth when a certain parameter $\varepsilon>0$, related to the interface thickness, tends to zero. In particular,…

Many mathematical models in different disciplines involve the formulation of free boundary problems, where the domain boundaries are not predefined. These models present unique challenges, notably the nonlinear coupling between the solution…

We study a diffuse interface model describing the evolution of the flow of a binary fluid in a Hele-Shaw cell. The model consists of a Cahn-Hilliard-Darcy (CHD) type system with transport and mass source. A relevant physical application is…

A considerable number of research works has been devoted to the study of tumor models. Several biophysical factors, such as cell proliferation, apoptosis, chemotaxis, angiogenesis and necrosis, have been discovered to have an impact on the…

In the present article the diffusion equation is used to model the spatio-temporal dynamics of a tumor, taking into account the heterogeneous of the medium. This approach makes it possible to take into account the complex geometric shape of…

In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a…

We study the free boundary of the porous medium equation with nonlocal drifts in dimension one. Under the assumption that the initial data has super-quadratic growth at the free boundary, we show that the solution is smooth in space and…

We investigate the stability and global existence of weak solutions to a free boundary problem governing the evolution of polymeric fluids. We construct weak solutions of the two-phase model by performing the asymptotic limit of a…