相关论文: Bifurcation analysis for a free boundary problem m…
We investigate the evolution of the surface of radiating stars by studying the asymptotic behaviour of exact solutions initiated via the stationary boundary condition. This boundary condition leads to a master equation in the form of a…
If a differential equation in a Banach manifold is invariant or quasi-invariant under the action of one or more Lie groups, then its stationary points cannot be isolated, so that classical linearized stability theorem does not apply to it.…
The physics of solid tumor growth can be considered at three distinct size scales: the tumor scale, the cell-extracellular matrix (ECM) scale and the sub-cellular scale. In this paper we consider the tumor scale in the interest of…
We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…
We investigate the general Porous Medium Equations with drift and source terms that model tumor growth. Incompressible limit of such models has been well-studied in the literature, where convergence of the density and pressure variables are…
We consider a coupled bulk-surface system of partial differential equations with nonlinear coupling modelling receptor-ligand dynamics. The model arises as a simplification of a mathematical model for the reaction between cell surface…
We consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. The model is derived by taking the incompressible limit of porous medium type equations, and the boundary instability of this model was recently studied…
In this work, we focus on the analytical and numerical study of a mathematical model for brain tumors with radiotherapy influence. Under certain assumptions on the given data in the model, we prove existence and uniqueness of a weak…
During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…
In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma, which includes an anisotropic nonlinear diffusion term with a diffusion velocity increasing with respect to vasculature. First, we prove the existence of…
A model of unsteady filtration (seepage) in a porous medium with capillary retention is considered. It leads to a free boundary problem for a generalized porous medium equation where the location of the boundary of the water mound is…
We propose a mathematical model for the growth and treatment dynamics of Undifferentiated Pleomorphic Sarcoma (UPS) based on a system of nonlinear differential equations. The model integrates Gompertz-type tumor growth with surface-area…
A generalisation of the Lie symmetry method is applied to classify a coupled system of reaction-diffusion equations wherein the nonlinearities involve arbitrary functions in the limit case in which one equation of the pair is quasi-steady…
In this paper we study the asymptotic behavior of solutions for a non-local non-autonomous scalar quasilinear parabolic problem in one space dimension. Our aim is to give a fairly complete description of the the forwards asymptotic behavior…
We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a…
We introduce here a new diffuse interface thermodynamically consistent non-isothermal model for tumor growth in presence of a nutrient in a domain $\Omega \subset \mathbb{R}^3$. In particular our system describes the growth of a tumor…
In this contribution, the non-local, integro-partial differential system of equations proposed by Hillen et al. (Bull. Math. Biol. 75, 2013, no.1, 161-184) to account for the the tumor growth paradox (or the observation that some incomplete…
A free boundary value problem related to the genesis of multispecies granular biofilms is presented. The granular biofilm is modelled as a spherical free boundary domain with radial symmetry. The proposed model is conceived in the framework…
Background and Objective: In an in-vivo situation, the tissue near the blood vessels is rich in oxygen supply compared to the one far from blood vessels. Hence, non-uniform oxygen distribution is observed in biological tissues. Our…
The low-density lipoprotein (LDL)/high-density lipoprotein (HDL)-cholesterol ratio has been shown a high correlation with the cardiovascular risk assessment. Is it possible to quantify the correlation mathematically? In this paper, we…