相关论文: Modeling oscillatory Microtubule--Polymerization
Dynamic instability of microtubules is considered using frameworks of non-linear thermodynamics and non-equilibrium reaction-diffusion systems. Stochastic assembly/disassembly phases in the polymerization dynamics of microtubules are…
We investigate a diffusive, stage-structured epidemic model with the maturation delay and freely-moving delay. Choosing delays and diffusive rates as bifurcation parameters, the only possible way to destabilize the endemic equilibrium is…
Oscillatory systems with time-delayed pulsatile feedback appear in various applied and theoretical research areas, and received a growing interest in the last years. For such systems, we report a remarkable scenario of destabilization of a…
Autonomous sustained oscillations are ubiquitous in living and nonliving systems. As open systems, far from thermodynamic equilibrium, they defy entropic laws which mandate convergence to stationarity. We present structural conditions on…
Protein phosphorylation cycles are important mechanisms of the post translational modification of a protein and as such an integral part of intracellular signaling and control. We consider the sequential phosphorylation and…
We numerically study the three-dimensional turbulence in a minimal model of an active fluid--the Toner-Tu-Swift-Hohenburg equation. For small activity, we observe bacterial turbulence, while for large activity, we uncover hitherto…
We investigate the microtubule polymerization dynamics with catastrophe and rescue events for three different confinement scenarios, which mimic typical cellular environments: (i) The microtubule is confined by rigid and fixed walls, (ii)…
Nonlinear oscillations of a bubble carrying a constant charge and suspended in a fluid, undergoing periodic forcing due to incident ultrasound are studied. The system exhibits period-doubling route to chaos and the presence of charge has…
A theoretical model of stabilization of a microtubule assembly due to microtubule-associated-proteins(MAP) is presented. MAPs are assumed to bind to the microtubule filaments, thus preventing their disintegration following hydrolysis and…
It is known from the wave-like motion of microtubules in motility assays that the piconewton forces that motors produce can be sufficient to bend the filaments. In cellular phenomena such as cytosplasmic streaming, molecular motors…
A theoretical analysis is presented to show the general occurrence of phase clusters in weakly, globally coupled oscillators close to a Hopf bifurcation. Through a reductive perturbation method, we derive the amplitude equation with a…
The periodic solutions of a type of nonlinear hyperbolic partial differential equations with a localized nonlinearity are investigated. For instance, these equations are known to describe several acoustical systems with fluid-structure…
Bursting is a periodic transition between a quiescent state and a state of repetitive spiking. The phenomenon is ubiquitous in a variety of neurophysical systems. We numerically study the dynamical properties of a normal form of subcritical…
We investigate the dynamics of an idealized model of microtubule growth that evolves by: (i) attachment of guanosine triphosphate (GTP) at rate lambda, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of…
We prove that time-periodic solutions arise via Hopf bifurcation in a finite closed system of coagulation-fragmentation equations. The system we treat is a variant of the Becker-Doering equations, in which clusters grow or shrink by…
Theoretical investigations of dynamical behavior in optical parametric oscillators (OPO) have generally assumed that the cavity detunings of the interacting fields are controllable parameters. However, OPOs are known to experience mode…
In aggregation-fragmentation processes, a steady state is usually reached in the long time limit. This indicates the existence of a fixed point in the underlying system of ordinary differential equations. The next simplest possibility is an…
We show that at the onset of a cyclic fold bifurcation, a birhythmic medium composed of glycolytic oscillators displays turbulent dynamics. By computing the largest Lyapunov exponent, the spatial correlation function, and the average…
Robust oscillations play crucial roles in a wide variety of biological processes and are often generated by deterministic mechanisms. However, stochastic fluctuations often generate complex perturbations of these deterministic oscillations,…
We investigate the non-linear dynamics of a two-dimensional film flowing down a finite heater, for a non-volatile and a volatile liquid. An oscillatory instability is predicted beyond a critical value of Marangoni number using linear…