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Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

We investigate a class of stochastic growth models involving competition between two phases in which one of the phases has a competitive advantage. The equilibrium populations of the competing phases are calculated using a mean field…

软凝聚态物质 · 物理学 2015-06-25 M. T. Batchelor , B. I. Henry , S. D. Watt

Initiation and development of a malignant tumor is a complex phenomenon that has critical stages determining its long time behavior. This phenomenon is mathematically described by means of various models: from simple heuristic models to…

种群与进化 · 定量生物学 2020-03-23 Yuri Kozitsky , Krzysztof Pilorz

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

种群与进化 · 定量生物学 2007-05-23 José F. Nieves , Marcelo R. Ubriaco

In this work, we present and analyze a system of PDEs, which models tumor growth by considering chemotaxis, active transport, and random effects. The stochasticity of the system is modelled by random initial data and Wiener noises that…

偏微分方程分析 · 数学 2023-12-12 Marvin Fritz , Luca Scarpa

A nutrient-limited model for avascular cancer growth including cell proliferation, motility and death is presented. The model qualitatively reproduces commonly observed morphologies for primary tumors, and the simulated patterns are…

统计力学 · 物理学 2011-03-09 S. C. Ferreira Junior , M. L. Martins , M. J. Vilela

An individual-based model of stochastic branching is proposed and studied, in which point particles drift in $\bar{\mathds{R}}_{+}:=[0,+\infty)$ towards the origin (edge) with unit speed, where each of them splits into two particles that…

动力系统 · 数学 2019-10-30 Yuri Kozitsky

Tumor growth has a number of features in common with a physical process known as molecular beam epitaxy. Both growth processes are characterized by the constraint of growth development to the body border, and surface diffusion of…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

In the present article we demonstrate a new hybrid model of tumor growth. Our model is stochastic by tumor population development and strongly deterministic in cell motility dynamics and spatial propagation. In addition, it has excellent…

其他定量生物学 · 定量生物学 2017-05-03 Yehor Surkov , Ihor Samofalov , Mironenko Anastasia

In this survey article, a variety of systems modeling tumor growth are discussed. In accordance with the hallmarks of cancer, the described models incorporate the primary characteristics of cancer evolution. Specifically, we focus on…

动力系统 · 数学 2023-03-21 Marvin Fritz

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

偏微分方程分析 · 数学 2017-05-23 Donatella Donatelli , Konstantina Trivisa

Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…

偏微分方程分析 · 数学 2016-02-17 Benoit Perthame , Nicolas Vauchelet

A two-dimensional free boundary model for the growth of multi-layer tumors has been proposed in [S. Cui, J. Escher: ARMA 191 (2009) 173-193] where the authors derive well-posedness in a functional analytic setting, the stationary solutions…

偏微分方程分析 · 数学 2012-04-12 Martin Kohlmann

A macroscopic model of the tumor Gompertzian growth is proposed. This approach is based on the energetic balance among the different cell activities, described by methods of statistical mechanics and related to the growth inhibitor factors.…

组织与器官 · 定量生物学 2017-08-23 Paolo Castorina , Dario Zappalá

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

偏微分方程分析 · 数学 2013-06-11 Martin Kohlmann

A macroscopic model of the tumor Gompertzian growth is proposed. The new approach is based on the energetic balance among the different cell activities, described by methods of statistical mechanics and related to the growth inhibitor…

细胞行为 · 定量生物学 2007-05-23 Paolo Castorina , Dario Zappala'

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

细胞行为 · 定量生物学 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

We develop a field theory-inspired stochastic model for description of tumour growth based on an analogy with an SI epidemic model, where the susceptible individuals (S) would represent the healthy cells and the infected ones (I), the…

生物物理 · 物理学 2017-05-30 Leonardo Mondaini

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…

数学物理 · 物理学 2010-11-09 Andrea Tosin
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