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Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

定量方法 · 定量生物学 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

Diabetes cases worldwide have risen steadily over the past decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain…

组织与器官 · 定量生物学 2014-03-05 S. M. Kissler , C. Cichowitz , S. Sankaranarayanan , D. M. Bortz

This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…

系统与控制 · 电气工程与系统科学 2024-01-31 Beatrice Sonzogni , José María Manzano , Marco Polver , Fabio Previdi , Antonio Ferramosca

This paper presents a control algorithm for creating an artificial pancreas for type 1 diabetes, factoring in input saturation for a practical application. By utilizing the parallel distributed compensation and Takagi-Sugeno Fuzzy model, we…

系统与控制 · 电气工程与系统科学 2024-08-21 Mohammadreza Ganji , Mahdi Pourgholi

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

计算机视觉与模式识别 · 计算机科学 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

Leveraging health administrative data (HAD) datasets for predicting the risk of chronic diseases including diabetes has gained a lot of attention in the machine learning community recently. In this paper, we use the largest health records…

应用统计 · 统计学 2019-04-09 Mathieu Ravaut , Hamed Sadeghi , Kin Kwan Leung , Maksims Volkovs , Laura C. Rosella

The Glucose-Insulin-Glucagon nonlinear model [1-4] accurately describes how the body responds to exogenously supplied insulin and glucagon in patients affected by Type I diabetes. Based on this model, we design infusion rates of either…

组织与器官 · 定量生物学 2019-06-19 Afroza Shirin , Fabio Della Rossa , Isaac Klickstein , John Russell , Francesco Sorrentino

Modern treatments for Type 1 diabetes (T1D) use devices known as artificial pancreata (APs), which combine an insulin pump with a continuous glucose monitor (CGM) operating in a closed-loop manner to control blood glucose levels. In…

机器学习 · 计算机科学 2018-12-04 Matthew O'Kelly , Aman Sinha , Justin Norden , Hongseok Namkoong

The Internet of Things (IoT) revolutionizes smart city domains such as healthcare, transportation, industry, and education. The Internet of Medical Things (IoMT) is gaining prominence, particularly in smart hospitals and Remote Patient…

分布式、并行与集群计算 · 计算机科学 2025-02-25 Alain Hennebelle , Qifan Dieng , Leila Ismail , Rajkumar Buyya

In this paper, a novel robust tracking control scheme for a general class of discrete-time nonlinear systems affected by unknown bounded uncertainty is presented. By solving a parameterized optimal tracking control problem subject to the…

系统与控制 · 电气工程与系统科学 2023-12-08 Alexandros Tanzanakis , John Lygeros

In type 2 diabetes (T2D) treatment, finding a safe and effective basal insulin dose is a challenge. The dose-response is highly individual and to ensure safety, people with T2D titrate by slowly increasing the daily insulin dose to meet…

系统与控制 · 电气工程与系统科学 2022-11-28 Sarah Ellinor Engell , Tinna Björk Aradóttir , Tobias K. S. Ritschel , Henrik Bengtsson , John Bagterp Jørgensen

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

其他定量生物学 · 定量生物学 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

Intensive care unit (ICU) patients exhibit erratic blood glucose (BG) fluctuations, including hypoglycemic and hyperglycemic episodes, and require exogenous insulin delivery to keep their BG in healthy ranges. Glycemic control via glycemic…

Type 2 Diabetes is a fast-growing, chronic metabolic disorder due to imbalanced insulin activity.The motion of this research is a comparative study of seven machine learning classifiers and an artificial neural network method to…

机器学习 · 计算机科学 2023-01-10 Md. Kowsher , Mahbuba Yesmin Turaba , Tanvir Sajed , M M Mahabubur Rahman

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

机器学习 · 计算机科学 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

定量方法 · 定量生物学 2021-02-24 Woo Seok Lee , Junghyo Jo , Taegeun Song

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

机器学习 · 计算机科学 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

其他定量生物学 · 定量生物学 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

Diabetes is currently one of the most common, dangerous, and costly diseases in the world that is caused by an increase in blood sugar or a decrease in insulin in the body. Diabetes can have detrimental effects on people's health if…

机器学习 · 计算机科学 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

机器学习 · 计算机科学 2026-04-27 Beyza Cinar , Maria Maleshkova