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The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…
Insulin resistance, a precursor to type 2 diabetes, is characterized by impaired insulin action in tissues. Current methods for measuring insulin resistance, while effective, are expensive, inaccessible, not widely available and hinder…
Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…
In this paper, models of the blood glucose (BG) dynamics in people with Type 1 diabetes (T1D) in response to moderate intensity aerobic activity are derived from physiology-based first principles and system identification experiments. We…
Type 1 diabetes (T1D) is a highly metabolically heterogeneous disease that cannot be adequately characterized by conventional biomarkers such as glycated hemoglobin (HbA1c). This study proposes an explainable deep learning framework that…
The rising global prevalence of diabetes necessitates early detection to prevent severe complications. While AI-powered prediction applications offer a promising solution, they require a responsive and scalable back-end architecture to…
Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. Clinical decision support systems incorporating artificial intelligence (AI-CDSS) can assist medical professionals in diagnosing type 2…
The mathematical modelling of biological systems has historically followed one of two approaches: comprehensive and minimal. In comprehensive models, the involved biological pathways are modelled independently, then brought together as an…
Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…
Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…
This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…
This study develops a cloud-based deep learning system for early prediction of diabetes, leveraging the distributed computing capabilities of the AWS cloud platform and deep learning technologies to achieve efficient and accurate risk…
Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…
In this paper, several advanced data-driven nonlinear identification techniques are compared on a specific problem: a simplified glucoregulatory system modeling example. This problem represents a challenge in the development of an…
In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…
Reliable optimal control is challenging when the dynamics of a nonlinear system are unknown and only infrequent, noisy output measurements are available. This work addresses this setting of limited sensing by formulating a Bayesian prior…
This paper reviews a wide selection of machine learning models built to predict both the presence of diabetes and the presence of undiagnosed diabetes using eight years of National Health and Nutrition Examination Survey (NHANES) data.…
Postprandial hyperglycemia, marked by the blood glucose level exceeding the normal range after consuming a meal, is a critical indicator of progression toward type 2 diabetes in people with prediabetes and in healthy individuals. A key…
To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…
Diabetes, a chronic condition that impairs how the body turns food into energy, i.e. blood glucose, affects 38 million people in the US alone. The standard treatment is to supplement carbohydrate intake with an artificial pancreas, i.e. a…