相关论文: Free boundary regularity for a tumor growth model …
The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…
In this paper, we study a tumor growth model where the growth is driven by nutrient availability and the tumor expands according to Darcy's law with a mechanical pressure resulting from the incompressibility of the cells. Our focus is on…
This article deals with the variable coefficient thin obstacle problem in $n+1$ dimensions. We address the regular free boundary regularity, the behavior of the solution close to the free boundary and the optimal regularity of the solution…
We consider viscosity solution to one-phase free boundary problems for general fully nonlinear operators and free boundary condition depending on the normal vector. We show existence of viscosity solutions via the Perron's method and we…
In this paper we study a free boundary problem for the growth of multi-layer tumors in necrotic phase. The tumor region is strip-like and divided into necrotic region and proliferating region with two free boundaries. The upper free…
In this paper we make rigorous mathematical analysis to a free boundary problem modeling the growth of necrotic tumors. A remarkable feature of this free boundary problem is that it contains two different-type free surfaces: One is the…
In this paper, we present a rigorous mathematical analysis of a free boundary problem modeling the growth of a vascular solid tumor with a necrotic core. If the vascular system supplies the nutrient concentration $\sigma$ to the tumor at a…
At the continuous level, we consider two types of tumor growth models: the cell density model, which is based on the fluid mechanical construction, is more favorable for scientific interpretation and numerical simulations; and the free…
We study the existence and multiplicity of solutions of the following free boundary problem $$ (P)\left\{ \begin{array}{rcll} \del u &=& \lam ( \eps +(1-\eps ) H(u-\mu))~ \hspace{3mm}&\text{in}~\Omega (t)\\ u&=&…
In this article we study for the first time the regularity of the free boundary in the one-phase free boundary problem driven by a general nonlocal operator. Our main results establish that the free boundary is $C^{1,\alpha}$ near regular…
Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…
We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…
In this article we use flatness improvement argument to study the regularity of the free boundary for the biharmonic obstacle problem with zero obstacle. Assuming that the solution is almost one-dimensional, and that the non-coincidence set…
In this paper we deal with a free boundary problem modeling the growth of nonnecrotic tumors.The tumor is treated as an incompressible fluid, the tissue elasticity is neglected and no chemical inhibitor species are present. We re-express…
In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…
We study the regularity of the free boundary in the fully nonlinear thin obstacle problem. Our main result establishes that the free boundary is $C^1$ near regular points.
We study regularity properties of the free boundary for solutions of the porous medium equation with the presence of drift. We show the $C^{1,\alpha}$ regularity of the free boundary, when the solution is directionally monotone in space…
In this paper we study the existence, the optimal regularity of solutions, and the regularity of the free boundary near the so-called \emph{regular points} in a thin obstacle problem that arises as the local extension of the obstacle…
We study the regularity of the "free surface" in boundary obstacle problems. We show that near a non-degenerate point the free boundary is a $C^{1,\alpha}$ $(n-2)$-dimensional surface in $\real^{n-1}$.
A two-dimensional free boundary model for the growth of multi-layer tumors has been proposed in [S. Cui, J. Escher: ARMA 191 (2009) 173-193] where the authors derive well-posedness in a functional analytic setting, the stationary solutions…