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We study the optimal control problem of a free boundary PDE model describing the growth of multilayered tumor tissue in vitro. We seek the optimal amount of tumor growth inhibitor that simultaneously minimizes the thickness of the tumor…

偏微分方程分析 · 数学 2024-10-21 Xinyue Evelyn Zhao , Yixiang Wu , Rachel Leander , Wandi Ding , Suzanne Lenhart

We show how a fixed point based boundary-layer analysis technique can be used to obtain the steady-state particle density profiles of driven exclusion processes on two-lane systems with open boundaries. We have considered two distinct…

统计力学 · 物理学 2015-06-11 Vandana Yadav , Rajesh Singh , Sutapa Mukherji

This paper concerns the free boundary problem of an epidemic model. The spatial movements of the infectious agents and the infective humans are approximated by nonlocal diffusion operators. Especially, both the growth rate of the agents and…

偏微分方程分析 · 数学 2024-06-11 Xueping Li , Lei Li , Mingxin Wang

Biofilms are ubiquitous macro-colonies of bacteria that develop at various interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms starts with the attachment of individual bacteria to an interface, where they…

生物物理 · 物理学 2016-11-03 Sarah Trinschek , Karin John , Uwe Thiele

We consider an epidemic model with nonlocal diffusion and free boundaries, which describes the evolution of an infectious agents with nonlocal diffusion and the infected humans without diffusion, where humans get infected by the agents, and…

偏微分方程分析 · 数学 2019-12-06 Meng Zhao , Yang Zhang , Wan-Tong Li , Yihong Du

The cell motility problem has been investigated for a long time. Today, many biologists, physicists, and mathematicians are looking for new research instruments for this process. A simple 2D model of a free-boundary cell moving on a…

细胞行为 · 定量生物学 2024-01-03 Vitaly Chernik , Pavel Buklemishev

A model for ionic and electronic grain boundary transport through thin films, scales or membranes with columnar grain structure is introduced. The grain structure is idealized as a lattice of identical hexagonal cells - a honeycomb pattern.…

材料科学 · 物理学 2017-05-05 M. P. Tautschnig , N. M. Harrison , M. W. Finnis

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

偏微分方程分析 · 数学 2013-03-18 Shangbin Cui

We study a two-dimensional free boundary problem that models motility of eukaryotic cells on substrates. This problem consists of an elliptic equation describing the flow of cytoskeleton gel coupled with a convection-diffusion PDE for the…

偏微分方程分析 · 数学 2017-07-12 Leonid Berlyand , Jan Fuhrmann , Volodymyr Rybalko

We attempt to describe surface defects in smectic A thin films by formulating a free discontinuity problem - that is, a variational problem in which the order parameter is allowed to have jump discontinuities on some (unknown) set. The free…

偏微分方程分析 · 数学 2023-03-10 John M. Ball , Giacomo Canevari , Bianca Stroffolini

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

偏微分方程分析 · 数学 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

This paper involves a diffusive epidemic model whose domain has one free boundary with the Stefan boundary condition, and one fixed boundary subject to the usual homogeneous Dirichlet or Neumann condition. By using the standard upper and…

偏微分方程分析 · 数学 2024-05-03 Xueping Li , Lei Li , Ying Xu , DanDan Zhu

We present a collision model for phase-resolved Direct Numerical Simulations of sediment transport that couple the fluid and particles by the Immersed Boundary Method. Typically, a contact model for these types of simulations comprises a…

流体动力学 · 物理学 2017-04-18 Edward Biegert , Bernhard Vowinckel , Eckart Meiburg

In this paper, we present a continuum model for the dynamics of low angle grain boundaries in two dimensions based on the motion of constituent dislocations of the grain boundaries. The continuum model consists of an equation for the motion…

材料科学 · 物理学 2018-06-13 Luchan Zhang , Yang Xiang

The theory of degenerate parabolic equations of the forms \[ u_t=(\Phi(u_x))_{x} \quad {\rm and} \quad v_{t}=(\Phi(v))_{xx} \] is used to analyze the process of contour enhancement in image processing, based on the evolution model of…

动力系统 · 数学 2007-05-23 G. I. Barenblatt , J. L. Vazquez

This paper studies the boundary behaviour at mechanical equilibrium at the ends of a finite interval of a class of systems of interacting particles with monotone decreasing repulsive force. Our setting covers pile-ups of dislocations,…

偏微分方程分析 · 数学 2016-09-13 Cameron Hall , Thomas Hudson , Patrick van Meurs

The use of thin liquid films has expanded beyond lubrication and coatings, and into applications in actuators and adaptive optical elements. In contrast to their predecessors, whose dynamics can be typically captured by modelling infinite…

流体动力学 · 物理学 2023-07-06 Israel Gabay , Vesna Bacheva , Dotan Ilssar , Moran Bercovici , Antonio Ramos , Amir Gat

In this paper we study a linearized eigenvalue problem derived from a a free boundary problem modeling the growth of a tumor containing two species of cells: proliferating cells and quiescent cells. The reduced form of this eigenvalue…

偏微分方程分析 · 数学 2018-10-19 Shangbin Cui , Jiayue Zheng

A new method for the solution of initial-boundary value problems for evolution PDEs recently introduced by Fokas is generalised to multidimensions. Also the relation of this method with the method of images and with the classical integral…

凝聚态物理 · 物理学 2007-05-23 Athanassios S. Fokas , Daniel ben-Avraham

We prove local existence for classical solutions of a free boundary problem which arises in one of the biological selection models proposed by Brunet and Derrida, [2] and Durrett and Remenik, [14]. The problem we consider describes the…

概率论 · 数学 2018-08-09 Jimyeong Lee
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