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相关论文: Tumor Growth with Nutrients: Regularity and Stabil…

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Some clinical and pre-clinical data suggests that treating some tumors at a mild, patient-specific dose might delay resistance to treatment and increase survival time. A recent mathematical model with sensitive and resistant tumor cells…

动力系统 · 数学 2022-12-01 Frank Alvarez , Yannick Viossat

A major goal of modern computational biology is to simulate the collective behaviour of large cell populations starting from the intricate web of molecular interactions occurring at the microscopic level. In this paper we describe a…

生物物理 · 物理学 2007-05-23 Roberto Chignola , Edoardo Milotti

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

种群与进化 · 定量生物学 2007-05-23 José F. Nieves , Marcelo R. Ubriaco

We examine a lattice model of tumor growth where survival of tumor cells depends on the supplied nutrients. When such a supply is random, the extinction of tumors belongs to the directed percolation universality class. However, when the…

统计力学 · 物理学 2015-05-30 Antonio Luis Ferreira , Dorota Lipowska , Adam Lipowski

We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…

偏微分方程分析 · 数学 2024-07-29 Matteo Fornoni

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

偏微分方程分析 · 数学 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines…

Understanding the untreated tumor growth kinetics and its intrinsic findings is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows to simulate changes in surface charge density…

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

动力系统 · 数学 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…

动力系统 · 数学 2018-03-15 Veli Shakhmurov , Akif Maharramov , Bunyad Shahmurzada

Mechanical models of tumor growth based on a porous medium approach have been attracting a lot of interest both analytically and numerically. In this paper, we study the stability properties of a finite difference scheme for a model where…

数值分析 · 数学 2021-05-24 Noemi David , Xinran Ruan

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

细胞行为 · 定量生物学 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…

组织与器官 · 定量生物学 2019-07-16 Joe Eyles , John F. King , Vanessa Styles

We consider the problem of the long time dynamics for a diffuse interface model for tumor growth. The model describes the growth of a tumor surrounded by host tissues in the presence of a nutrient and consists in a Cahn-Hilliard-type…

偏微分方程分析 · 数学 2018-10-30 Alain Miranville , Elisabetta Rocca , Giulio Schimperna

Recently, we have proposed a nutrient-limited model for the avascular growth of tumors including cell proliferation, motility and death \cite{jr}, that, qualitatively reproduces commonly observed morphologies for carcinomas {\it in situ}.…

凝聚态物理 · 物理学 2009-11-07 S. C. Ferreira , M. L. Martins , M. J. Vilela

Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell…

生物物理 · 物理学 2007-05-23 P. Gerlee , A. R. A Anderson

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

In this paper, we develop a sharp interface tumor growth model to study the effect of the tumor microenvironment using a complex far-field geometry that mimics a heterogeneous distribution of vasculature. Together with different nutrient…

数值分析 · 数学 2020-03-20 Min-Jhe Lu , Chun Liu , John Lowengrub , Shuwang Li

Tumors are defined by their intense proliferation, but sometimes cancer cells turn senescent and stop replicating. In the stochastic cancer model in which all cells are tumorigenic, senescence is seen as the result of random mutations,…

组织与器官 · 定量生物学 2013-08-29 Caterina A. M. La Porta , Stefano Zapperi , James P. Sethna

In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…

组织与器官 · 定量生物学 2018-01-17 Veli Shakhmurov