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相关论文: Some protein interaction data do not exhibit power…

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Networks have been used to model many real-world phenomena to better understand the phenomena and to guide experiments in order to predict their behavior. Since incorrect models lead to incorrect predictions, it is vital to have a correct…

分子网络 · 定量生物学 2007-05-23 Natasa Przulj , Derek G. Corneil , Igor Jurisica

Understanding the mathematical properties of graphs underling biological systems could give hints on the evolutionary mechanisms behind these structures. In this article we perform a complete statistical analysis over thousands of graphs…

分子网络 · 定量生物学 2019-08-29 D. Gamermann , J. Triana , R. Jaime

In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate…

基因组学 · 定量生物学 2007-05-23 Santiago Schnell , Santo Fortunato , Sourav Roy

We present a simple model for the underlying structure of protein-protein pairwise interaction graphs that is based on the way in which proteins attach to each other in experiments such as yeast two-hybrid assays. We show that data on the…

分子网络 · 定量生物学 2007-05-23 Alun Thomas , Rob Cannings , Nicholas A. M. Monk , Chris Cannings

Several studies on real complex networks from different fields as biology, economy, or sociology have shown that the degree of nodes (number of edges connected to each node) follows a scale-free power-law distribution like $P(k)\approx…

生物物理 · 物理学 2007-05-23 J. C. Nacher , T. Yamada , S. Goto , M. Kanehisa , T. Akutsu

It has recently been demonstrated that many biological networks exhibit a scale-free topology where the probability of observing a node with a certain number of edges (k) follows a power law: i.e. p(k) ~ k^-g. This observation has been…

分子网络 · 定量生物学 2009-11-11 Eric J. Deeds , Orr Ashenberg , Eugene I. Shakhnovich

Scale-free networks, in which the distribution of the degrees obeys a power-law, are ubiquitous in the study of complex systems. One basic network property that relates to the structure of the links found is the degree assortativity, which…

物理与社会 · 物理学 2015-06-22 Oliver Williams , Charo I. Del Genio

A central claim in modern network science is that real-world networks are typically "scale free," meaning that the fraction of nodes with degree $k$ follows a power law, decaying like $k^{-\alpha}$, often with $2 < \alpha < 3$. However,…

物理与社会 · 物理学 2019-03-19 Anna D. Broido , Aaron Clauset

We analyze about two hundred naturally occurring networks with distinct dynamical origins to formally test whether the commonly assumed hypothesis of an underlying scale-free structure is generally viable. This has recently been questioned…

The scale free structure p(k)~k^{-gamma} of protein-protein interaction networks can be reproduced by a static physical model in simulation. We inspect the model theoretically, and find the key reason for the model to generate apparent…

分子网络 · 定量生物学 2015-06-26 Jingshan Zhang , Eugene I. Shakhnovich

We employed the random graph theory approach to analyze the protein-protein interaction database DIP (Feb. 2004), for seven species (S. cerevisiae, H. pylori, E. coli, C. elegans, H. sapiens, M. musculus and D. melanogaster). Several global…

分子网络 · 定量生物学 2007-05-23 Ka-Lok Ng , Chien-Hung Huang

Connectivity correlations play an important role in the structure of scale-free networks. While several empirical studies exist, there is no general theoretical analysis that can explain the largely varying behavior of real networks. Here,…

物理与社会 · 物理学 2009-11-13 Lazaros K. Gallos , Chaoming Song , Hernan A. Makse

It has recently been discovered that many biological systems, when represented as graphs, exhibit a scale-free topology. One such system is the set of structural relationships among protein domains. The scale-free nature of this and other…

种群与进化 · 定量生物学 2009-11-10 Eric J. Deeds , Eugene I. Shakhnovich

Network growth is currently explained through mechanisms that rely on node prestige measures, such as degree or fitness. In many real networks those who create and connect nodes do not know the prestige values of existing nodes, but only…

无序系统与神经网络 · 物理学 2007-05-23 Santo Fortunato , Alessandro Flammini , Filippo Menczer

Many biological networks have been labelled scale-free as their degree distribution can be approximately described by a powerlaw distribution. While the degree distribution does not summarize all aspects of a network it has often been…

分子网络 · 定量生物学 2007-05-23 M. P. H. Stumpf , P. J. Ingram , I. Nouvel , C. Wiuf

We test the claim by Yu et al. -- presented in Science 322, 104 (2008) -- that the degree distribution of the yeast (Saccharomyces cerevisiae) protein-interaction network is best approximated by a power law. Yu et al. consider three…

分子网络 · 定量生物学 2009-01-06 Aaron Clauset

Complex networks across various fields are often considered to be scale free -- a statistical property usually solely characterized by a power-law distribution of the nodes' degree $k$. However, this characterization is incomplete. In…

物理与社会 · 物理学 2023-10-24 Xiangyi Meng , Bin Zhou

Successive whole genome duplications have recently been firmly established in all major eukaryote kingdoms. It is not clear, however, how such dramatic evolutionary process has contributed to shape the large scale topology of…

分子网络 · 定量生物学 2007-05-23 K. Evlampiev , H. Isambert

The degree distribution of many biological and technological networks has been described as a power-law distribution. While the degree distribution does not capture all aspects of a network, it has often been suggested that its functional…

分子网络 · 定量生物学 2007-05-23 Michael P. H. Stumpf , Piers J. Ingram

Generally, the threshold of percolation in complex networks depends on the underlying structural characterization. However, what topological property plays a predominant role is still unknown, despite the speculation of some authors that…

统计力学 · 物理学 2009-03-14 Zhongzhi Zhang , Shuigeng Zhou , Tao Zou , Lichao Chen , Jihong Guan
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