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Alzheimer`s disease (AD)-related global healthcare cost is estimated to be $1 trillion by 2050. Currently, there is no cure for this disease; however, clinical studies show that early diagnosis and intervention helps to extend the quality…

计算机与社会 · 计算机科学 2020-05-27 Ning Wang , Fan Luo , Vishal Peddagangireddy , K. P. Subbalakshmi , R. Chandramouli

The path signature is a means of feature generation that can encode nonlinear interactions in the data as well as the usual linear features. It can distinguish the ordering of time-sequenced changes: for example whether or not the…

定量方法 · 定量生物学 2020-07-01 P. J. Moore , J. Gallacher , T. J. Lyons

Face morphing attacks have emerged as a potential threat, particularly in automatic border control scenarios. Morphing attacks permit more than one individual to use travel documents that can be used to cross borders using automatic border…

计算机视觉与模式识别 · 计算机科学 2023-03-27 Raghavendra Ramachandra , Sushma Venkatesh , Gaurav Jaswal , Guoqiang Li

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

图像与视频处理 · 电气工程与系统科学 2019-01-30 GuruRaj Awate

Alzheimer's disease is the most common cause of dementia, yet hard to diagnose precisely without invasive techniques, particularly at the onset of the disease. This work approaches image analysis and classification of synthetic…

图像与视频处理 · 电气工程与系统科学 2017-12-05 Wellington Pinheiro dos Santos , Ricardo Emmanuel de Souza , Plínio B. dos Santos Filho

Machine learning methods exploiting multi-parametric biomarkers, especially based on neuroimaging, have huge potential to improve early diagnosis of dementia and to predict which individuals are at-risk of developing dementia. To benchmark…

Mild cognitive impairment (MCI) is a high-risk dementia condition which progresses to probable Alzheimer's disease (AD) at approximately 10% to 15% per year. Characterization of group-level differences between two subtypes of MCI - stable…

神经元与认知 · 定量生物学 2021-06-15 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Li Wang , Dajiang Zhu

We introduce a wide and deep neural network for prediction of progression from patients with mild cognitive impairment to Alzheimer's disease. Information from anatomical shape and tabular clinical data (demographics, biomarkers) are fused…

机器学习 · 计算机科学 2020-04-01 Sebastian Pölsterl , Ignacio Sarasua , Benjamín Gutiérrez-Becker , Christian Wachinger

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

图像与视频处理 · 电气工程与系统科学 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

计算机视觉与模式识别 · 计算机科学 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke

Motivated by the following two observations: 1) people are aging differently under different conditions for changeable facial attributes, e.g., skin color may become darker when working outside, and 2) it needs to keep some unchanged facial…

计算机视觉与模式识别 · 计算机科学 2019-12-23 Haien Zeng , Hanjiang Lai , Jian Yin

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

计算机视觉与模式识别 · 计算机科学 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive…

机器学习 · 计算机科学 2023-08-22 Deniz Sezin Ayvaz , Inci M. Baytas

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

The brain-age gap is one of the most investigated risk markers for brain changes across disorders. While the field is progressing towards large-scale models, recently incorporating uncertainty estimates, no model to date provides the…

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

机器学习 · 计算机科学 2026-03-06 Nishan Mitra

Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…

医学物理 · 物理学 2021-11-25 Simoni Mishra

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

计算机视觉与模式识别 · 计算机科学 2020-09-11 Md Motiur Rahman Sagar , Martin Dyrba

In recent years, there has been significant development in the analysis of medical data using machine learning. It is believed that the onset of Age-related Macular Degeneration (AMD) is associated with genetic polymorphisms. However,…

计算机视觉与模式识别 · 计算机科学 2024-09-18 Yoichi Furukawa , Satoshi Kamiya , Yoichi Sakurada , Kenji Kashiwagi , Kazuhiro Hotta