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Alzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specificity. This study aims to detect significant…

图像与视频处理 · 电气工程与系统科学 2024-11-01 Milla E. Nielsen , Mads Nielsen , Mostafa Mehdipour Ghazi

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

机器学习 · 计算机科学 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Obesity is one of the most important public health problems that the world is facing today. A recent trend is in the development of intervention tools that predict BMI using facial images for weight monitoring and management to combat…

计算机视觉与模式识别 · 计算机科学 2022-04-22 Hera Siddiqui , Ajita Rattani , Karl Ricanek , Twyla Hill

Purpose: Age biases have been identified as an essential factor in the diagnosis of ASD. The objective of this study was to compare the effect of different age groups in classifying ASD using morphological features (MF) and morphological…

图像与视频处理 · 电气工程与系统科学 2023-08-16 Gokul Manoj , Sandeep Singh Sengar , Jac Fredo Agastinose Ronickom

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

基因组学 · 定量生物学 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak

While a large body of research has formally identified apolipoprotein E (APOE) as a major genetic risk marker for Alzheimer disease, accumulating evidence supports the notion that other risk markers may exist. The traditional…

定量方法 · 定量生物学 2020-03-13 Ning An , Liuqi Jin , Huitong Ding , Jiaoyun Yang , Jing Yuan

Early detection of Alzheimer's disease (AD) and identification of potential risk/beneficial factors are important for planning and administering timely interventions or preventive measures. In this paper, we learn a disease model for AD…

机器学习 · 计算机科学 2018-12-04 Parvathy Sudhir Pillai , Tze-Yun Leong

Facial feature tracking is an active area in computer vision due to its relevance to many applications. It is a nontrivial task, since faces may have varying facial expressions, poses or occlusions. In this paper, we address this problem by…

计算机视觉与模式识别 · 计算机科学 2017-09-19 Yue Wu , Zuoguan Wang , Qiang Ji

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Ángel de la Vega Jiménez

The ethical, social and legal issues surrounding facial analysis technologies have been widely debated in recent years. Key critics have argued that these technologies can perpetuate bias and discrimination, particularly against…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Marco Rondina , Fabiana Vinci , Antonio Vetrò , Juan Carlos De Martin

Genome-wide association studies (GWAS) offer new opportunities to identify genetic risk factors for Alzheimer's disease (AD). Recently, collaborative efforts across different institutions emerged that enhance the power of many existing…

Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression…

机器学习 · 计算机科学 2018-12-07 Vipul Satone , Rachneet Kaur , Faraz Faghri , Mike A Nalls , Andrew B Singleton , Roy H Campbell

Diagnosing Alzheimer's disease (AD) involves a deliberate diagnostic process owing to its innate traits of irreversibility with subtle and gradual progression. These characteristics make AD biomarker identification from structural brain…

机器学习 · 计算机科学 2022-07-28 Ahmad Wisnu Mulyadi , Wonsik Jung , Kwanseok Oh , Jee Seok Yoon , Heung-Il Suk

Facial attribute analysis has received considerable attention when deep learning techniques made remarkable breakthroughs in this field over the past few years. Deep learning based facial attribute analysis consists of two basic sub-issues:…

计算机视觉与模式识别 · 计算机科学 2019-10-29 Xin Zheng , Yanqing Guo , Huaibo Huang , Yi Li , Ran He

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the…

定量方法 · 定量生物学 2025-08-26 Muheng Shang , Jin Zhang , Junwei Han , Lei Du

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

计算机视觉与模式识别 · 计算机科学 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Obesity is a major health problem, increasing the risk of various major chronic diseases, such as diabetes, cancer, and stroke. While the role of obesity identified by cross-sectional BMI recordings has been heavily studied, the role of BMI…

机器学习 · 计算机科学 2024-12-03 Md Mozaharul Mottalib , Jessica C Jones-Smith , Bethany Sheridan , Rahmatollah Beheshti

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

机器学习 · 计算机科学 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos