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Genome-wide association studies (GWAS) have achieved great success in the genetic study of Alzheimer's disease (AD). Collaborative imaging genetics studies across different research institutions show the effectiveness of detecting genetic…

The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers. However, to…

机器学习 · 计算机科学 2021-09-28 Raphael Ronge , Kwangsik Nho , Christian Wachinger , Sebastian Pölsterl

Recently, recognition of gender from facial images has gained a lot of importance. There exist a handful of research work that focus on feature extraction to obtain gender specific information from facial images. However, analyzing…

计算机视觉与模式识别 · 计算机科学 2017-12-06 Avirup Bhattacharyya , Rajkumar Saini , Partha Pratim Roy , Debi Prosad Dogra , Samarjit Kar

Face morphing attacks have raised critical concerns as they demonstrate a new vulnerability of Face Recognition Systems (FRS), which are widely deployed in border control applications. The face morphing process uses the images from multiple…

计算机视觉与模式识别 · 计算机科学 2020-09-22 Sushma Venkatesh , Kiran Raja , Raghavendra Ramachandra , Christoph Busch

Early diagnosis of Alzheimer's disease plays a key role in understanding the degree of the patient's mental decline and determining preventive therapies. In this study, we introduce WaveletBrain, a novel representation of the white and gray…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Majid Masoumi , Matthew Toews , Herve Lombaert

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…

计算与语言 · 计算机科学 2024-12-02 Junan Li , Yunxiang Li , Yuren Wang , Xixin Wu , Helen Meng

Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…

统计方法学 · 统计学 2024-07-17 Jérémie Lespinasse , Carole Dufouil , Cécile Proust-Lima , the MEMENTO study group

Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…

机器学习 · 计算机科学 2023-11-08 Xulong Wang , Yu Zhang , Menghui Zhou , Tong Liu , Jun Qi , Po Yang

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

定量方法 · 定量生物学 2020-03-11 Razvan V. Marinescu

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Alzheimer's Disease (AD) and related dementia are a growing global health challenge due to the aging population. In this paper, we present ADMarker, the first end-to-end system that integrates multi-modal sensors and new federated learning…

Research question: This study aims to find whether other neurostructural measurements could be added and combined with the state-of-the-art Alzheimer's imaging marker called MSSM to improve sensitivity to neurodegeneration in Alzheimer's…

神经元与认知 · 定量生物学 2024-09-24 Jinhee Jang , Geonwoo Baek , Ikbeom Jang

Early diagnosis of Alzheimer's disease is a challenge because the existing methodologies do not identify the patients in their preclinical stage, which can last up to a decade prior to the onset of clinical symptoms. Several research…

机器学习 · 计算机科学 2024-01-03 Vivek Kumar Tiwari , Premananda Indic , Shawana Tabassum

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in this early phase of disease are challenging due to the slow…

应用统计 · 统计学 2020-03-10 Dan Li , Samuel Iddi , Paul S. Aisen , Wesley K. Thompson , Michael C. Donohue

Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…

Understanding the distinction between causation and correlation is critical in Alzheimer's disease (AD) research, as it impacts diagnosis, treatment, and the identification of true disease drivers. This experiment investigates the…

人工智能 · 计算机科学 2025-06-13 Hamzah Dabool , Raghad Mustafa

Alzheimer's disease is a neurogenerative disease that alters memories, cognitive functions leading to death. Early diagnosis of the disease, by detection of the preliminary stage, called Mild Cognitive Impairment (MCI), remains a…

图像与视频处理 · 电气工程与系统科学 2020-12-03 Achraf Ben Miled , Taoufik Yeferny , Amira ben Rabeh

State-of-the-art face recognition (FR) approaches have shown remarkable results in predicting whether two faces belong to the same identity, yielding accuracies between 92% and 100% depending on the difficulty of the protocol. However, the…

计算机视觉与模式识别 · 计算机科学 2022-05-30 Stefan Hörmann , Tianlin Kong , Torben Teepe , Fabian Herzog , Martin Knoche , Gerhard Rigoll

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani