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Quality molecular representations are key to foundation model development in bio-medical research. Previous efforts have typically focused on a single representation or molecular view, which may have strengths or weaknesses on a given task.…

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

定量方法 · 定量生物学 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

图像与视频处理 · 电气工程与系统科学 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Background:Cognitive assessments represent the most common clinical routine for the diagnosis of Alzheimer's Disease (AD). Given a large number of cognitive assessment tools and time-limited office visits, it is important to determine a…

定量方法 · 定量生物学 2020-11-16 Bo Peng , Xiaohui Yao , Shannon L. Risacher , Andrew J. Saykin , Li Shen , Xia Ning

Multimodal Large Language Models (MLLMs) have recently been explored as face verification systems that determine whether two face images are of the same person. Unlike dedicated face recognition systems, MLLMs approach this task through…

计算机视觉与模式识别 · 计算机科学 2026-03-27 Ünsal Öztürk , Hatef Otroshi Shahreza , Sébastien Marcel

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

机器学习 · 计算机科学 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Alzheimer's disease has an increasing prevalence in the population world-wide, yet current diagnostic methods based on recommended biomarkers are only available in specialized clinics. Due to these circumstances, Alzheimer's disease is…

Multimorbidity, or the presence of several medical conditions in the same individual, has been increasing in the population, both in absolute and relative terms. However, multimorbidity remains poorly understood, and the evidence from…

Alzheimer's Disease (AD) is an irreversible neurodegenerative disorder affecting millions of individuals today. The prognosis of the disease solely depends on treating symptoms as they arise and proper caregiving, as there are no current…

图像与视频处理 · 电气工程与系统科学 2024-12-17 Prayas Sanyal , Srinjay Mukherjee , Arkapravo Das , Anindya Sen

To understand multifactorial conditions such as Alzheimers disease (AD) we need brain signatures that predict the impact of multiple pathologies and their interactions. To help uncover the relationships between brain circuits and cognitive…

Automated face recognition and identification softwares are becoming part of our daily life; it finds its abode not only with Facebook's auto photo tagging, Apple's iPhoto, Google's Picasa, Microsoft's Kinect, but also in Homeland Security…

计算机视觉与模式识别 · 计算机科学 2015-06-22 Poonam Yadav

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…

Multiple types or views of data (e.g. genetics, proteomics) measured on the same set of individuals are now popularly generated in many biomedical studies. A particular interest might be the detection of sample subgroups (e.g. subtypes of…

统计方法学 · 统计学 2025-05-09 Kaifeng Yang , Thierry Chekouo , Sandra E. Safo

In an era where the global population is aging significantly, cognitive impairments among the elderly have become a major health concern. The need for effective assistive technologies is clear, and facial recognition systems are emerging as…

计算机视觉与模式识别 · 计算机科学 2023-10-11 Li He

Biases inherent in both data and algorithms make the fairness of widespread machine learning (ML)-based decision-making systems less than optimal. To improve the trustfulness of such ML decision systems, it is crucial to be aware of the…

计算机视觉与模式识别 · 计算机科学 2022-08-30 Biying Fu , Naser Damer

Based on a combined data set of 4000 high resolution facial scans, we introduce a non-linear morphable face model, capable of producing multifarious face geometry of pore-level resolution, coupled with material attributes for use in…

计算机视觉与模式识别 · 计算机科学 2020-04-27 Ruilong Li , Karl Bladin , Yajie Zhao , Chinmay Chinara , Owen Ingraham , Pengda Xiang , Xinglei Ren , Pratusha Prasad , Bipin Kishore , Jun Xing , Hao Li

People are living longer than ever before, and with this arises new complications and challenges for humanity. Among the most pressing of these challenges is of understanding the role of aging in the development of dementia. This paper is…

统计方法学 · 统计学 2018-08-07 Jonathan P Williams , Curtis B Storlie , Terry M Therneau , Clifford R Jack , Jan Hannig