相关论文: Nonlinear multidomain model for nerve bundles with…

We present a dynamical system approach for the control of a nonlinear dynamical system by defining the control problem in a Fiber bundle framework. The constructive procedure derived results in the generation of a NHIM/NAIM which…

We devise a method for predicting certain receptor-ligand binding behaviors, based on stochastic dynamical modelling. We consider the dynamics of a receptor binding to a ligand on the cell membrane, where the receptor and ligand perform…

The slow dynamics of nearly stationary patterns in a FitzHugh-Nagumo model are studied using a phase dynamics approach. A Cross-Newell phase equation describing slow and weak modulations of periodic stationary solutions is derived. The…

This paper attempts to review our studies on the propagation of signals in nerves over the past decade. The need for interdisciplinary studies is stressed that helps to understand the physical mechanisms of coupling the electrical,…

Neural activity patterns related to behavior occur at many scales in time and space from the atomic and molecular to the whole brain. Here we explore the feasibility of interpreting neurophysiological data in the context of many-body…

We consider a nonlinear drift-diffusion system for multiple charged species in a porous medium in 2D and 3D with periodic microstructure. The system consists of a transport equation for the concentration of the species and Poisson's…

We propose a nonlinear one-dimensional FitzHugh--Nagumo neuronal model with an asymmetric potential driven by both a high-frequency and a low-frequency signal. Our numerical analysis focuses on the influence of a state-dependent time delay…

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or…

The behavior of a non-conductive quasi-planar lipid membrane in an electrolyte and in a static (DC) electric field is investigated theoretically in the nonlinear (Poisson-Boltzmann) regime. Electrostatic effects due to charges in the…

We present a microscopic approach for the coupling of cortical activity, as resulting from proper dipole currents of pyramidal neurons, to the electromagnetic field in extracellular fluid in presence of diffusion and Ohmic conduction. As a…

We present a novel mathematical approach to model noise in dynamical systems. We do so by considering dynamics of a chain of diffusively coupled Nagumo cells affected by noise. We show that the noise in transmembrane current can be…

Multi-compartment Hodgkin-Huxley models are biophysical models of how electrical signals propagate throughout a neuron, and they form the basis of our knowledge of neural computation at the cellular level. However, these models have many…

We study the long-time behavior of non-autonomous stochastic FitzHugh-Nagumo systems on thin domains. As the $(n+ 1)$-dimensional thin domains collapses onto an n-dimensional domain, an n-dimensional limiting FitzHugh-Nagumo system is…

We propose a general multiscale approach for the mechanical behavior of three-dimensional networks of macromolecules undergoing strain-induced unfolding. Starting from a (statistically based) energetic analysis of the macromolecule…

The dynamics of a membrane coupled to an active fluid on top of a substrate is considered theoretically. It is assumed that the director field of the active fluid has rotational symmetry in the membrane plane. This situation is likely to be…

Neuronal models based on the Hodgkin-Huxley equation form a fundamental framework in the field of computational neuroscience. While the neuronal state is often modeled deterministically, experimental recordings show stochastic fluctuations,…

The dynamic behavior of bundles of actin filaments growing against a loaded obstacle is investigated through a generalized version of the standard multi filaments Brownian Ratchet model in which the (de)polymerizing filaments are treated…

The bidomain model is the standard model for cardiac electrophysiology. In this paper, we investigate the instability and asymptotic behavior of planar fronts and planar pulses of the bidomain Allen-Cahn equation and the bidomain…

Action potential propagation along the axons and across the dendrites is the foundation of the electrical activity observed in the brain and the rest of the central nervous system. Theoretical and numerical modeling of this action potential…

Out-of-equilibrium behavior is explored in the one-dimensional anisotropic $XY$ model. Initially preparing the system in the isotropic $XX$ model with a linearly varying magnetic field to create a domain-wall magnetization profile, dynamics…