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The animal nervous system offers a model of computation combining digital reliability and analog efficiency. Understanding how this sweet spot can be realized is a core question of neuromorphic engineering. To this aim, this paper explores…

系统与控制 · 电气工程与系统科学 2026-02-19 Michelangelo Bin , Alessandro Cecconi , Lorenzo Marconi

We propose a neural network model of multi-neuron interacting system that simulates neurons to interact each other through the surroundings of neuronal cell bodies. We physically model the neuronal cell surroundings, include the dendrites,…

神经元与认知 · 定量生物学 2021-07-05 Yu-Juan Sun , Wei-Min Zhang

We study the effects of noise on stationary pulse solutions (bumps) in spatially extended neural fields. The dynamics of a neural field is described by an integrodifferential equation whose integral term characterizes synaptic interactions…

斑图形成与孤子 · 物理学 2012-05-15 Zachary P. Kilpatrick , Bard Ermentrout

A common mechanism for intracellular transport is the use of controlled deformations of the membrane to create spherical or tubular buds. While the basic physical properties of homogeneous membranes are relatively well-known, the effects of…

In this paper, we study an excitable, biophysical system that supports wave propagation of nerve impulses. We consider a slow-fast, FitzHugh-Rinzel neuron model where only the membrane voltage interacts diffusively, giving rise to the…

混沌动力学 · 物理学 2021-11-03 A. Mondal , A. Mondal , S. Kumar Sharma , R. Kumar Upadhyay , C. G. Antonopoulos

Understanding how external stimuli propagate in neural systems is an important challenge in the fields of neuroscience and nonlinear dynamics. Despite extensive studies over several decades, this problem remains poorly understood. In this…

神经元与认知 · 定量生物学 2025-03-13 L. Messee Goulefack , C. Masoller , R. Yamapi , C. Anteneodo

We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the…

神经元与认知 · 定量生物学 2015-11-20 Anastasia I. Lavrova , Michael A. Zaks , Lutz Schimansky-Geier

A mechanical model and numerical method for structural membranes implied by all isosurfaces of a level-set function in a three-dimensional bulk domain are proposed. The mechanical model covers large displacements in the context of the…

计算工程、金融与科学 · 计算机科学 2023-08-02 Thomas-Peter Fries , Michael W. Kaiser

Here we present a study of stochastic resonance in an extended FitzHugh-Nagumo system with a field dependent activator diffusion. We show that the system response (here measured through the output signal-to-noise ratio) is enhanced due to…

软凝聚态物质 · 物理学 2009-11-11 C. J. Tessone , H. S. Wio

Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

软凝聚态物质 · 物理学 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

The extracellular space has an ambiguous role in neuroscience. It is present in every physiologically relevant system and often used as a measurement site in experimental recordings, but it has received subordinate attention compared to the…

神经元与认知 · 定量生物学 2017-05-02 Jurgis Pods

It is argued that continuum realisations of distributions of collisionless charged particles should accommodate a dynamically evolving number of electric currents even if the continuum is composed of only one species of particle, such as…

等离子体物理 · 物理学 2008-11-26 D. A. Burton , J. Gratus , R. W. Tucker

We establish the existence and nonlinear stability of travelling pulse solutions for the discrete FitzHugh-Nagumo equation with infinite-range interactions close to the continuum limit. For the verification of the spectral properties, we…

动力系统 · 数学 2019-06-07 W. M. Schouten , H. J. Hupkes

Living cells move thanks to assemblies of actin filaments and myosin motors that range from very organized striated muscle tissue to disordered intracellular bundles. The mechanisms powering these disordered structures are debated, and all…

生物物理 · 物理学 2017-09-26 Martin Lenz

In this paper we deal with a feedback control design for the action potential of a neuronal membrane in relation with the non-linear dynamics of the Hodgkin-Huxley mathematical model. More exactly, by using an external current as a control…

最优化与控制 · 数学 2020-04-22 Cecilia Cavaterra , Denis Enachescu , Gabriela Marinoschi

We explore a biomimetic model that simulates a cell, with the internal cytoplasm represented by a two-dimensional circular domain and the external cortex by a surrounding ring, both modeled using FitzHugh-Nagumo systems. The external ring…

斑图形成与孤子 · 物理学 2025-01-08 Daniel Cebrián-Lacasa , Marcin Leda , Andrew B. Goryachev , Lendert Gelens

We study a phenomenological electropermeabilization model in a periodic medium representing biological tissue. Starting from a cell-level model describing the electric potential and the degree of porosity, we perform dimension analysis to…

偏微分方程分析 · 数学 2026-02-03 Tobias Gebäck , Ioanna Motschan-Armen , Irina Pettersson

Mathematical models for excitable cells are commonly based on cable theory, which considers a homogenized domain and spatially constant ionic concentrations. Although such models provide valuable insight, the effect of altered ion…

计算工程、金融与科学 · 计算机科学 2019-11-11 A. J. Ellingsrud , A. Solbrå , G. T. Einevoll , G. Halnes , M. E. Rognes

The physical basis of flagellar and ciliary beating is a major problem in biology which is still far from completely understood. The fundamental cytoskeleton structure of cilia and flagella is the axoneme, a cylindrical array of microtubule…

生物物理 · 物理学 2017-03-10 David Oriola , Hermes Gadêlha , Jaume Casademunt

We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

神经元与认知 · 定量生物学 2013-02-18 Vesna Vuksanović , Philipp Hövel