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We study a system of differential equation simulating transport phenomena in active structured media. The model is a generalization of the McKean s modification of the celebrated FitzHugh--Nagumo system, describing the nerve impulse…

数学物理 · 物理学 2015-06-11 Wojciech Likus , Vsevolod A. Vladimirov

We investigate a possibility of realization of structurally stable chaotic dynamics in neural systems. The considered model of interacting neurons consists of a pair of coupled FitzHugh-Nagumo systems, with the parameters being periodically…

混沌动力学 · 物理学 2017-03-07 Alexey Yu. Jalnine

Using the FitzHugh-Nagumo equations to represent the oscillatory electrical behavior of beta-cells, we develop a coupled oscillator network model with cubic lattice topology, showing that the emergence of pacemakers or hubs in the system…

生物物理 · 物理学 2022-06-28 Stefano Scialla , Alessandro Loppini , Marco Patriarca , Els Heinsalu

In this paper, the transport phenomena of synaptic electric impulses are considered. The FitzHugh--Nagumo and FitzHugh--Rinzel models appear mathematically appropriate for evaluating these scientific issues. Moreover, applications of such…

数学物理 · 物理学 2023-06-13 Monica De Angelis

We introduce a method for computing probabilities for spontaneous activity and propagation fail- ure of the action potential in spatially extended, conductance-based neuronal models subject to channel noise, based on statistical properties…

神经元与认知 · 定量生物学 2020-01-16 Martin Sauer , Wilhelm Stannat

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

应用统计 · 统计学 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…

生物物理 · 物理学 2012-12-18 Jarrett L. Lancaster , Esther M. Leise , Edward H. Hellen

We consider a mesoscopic model for a spatially extended FitzHugh-Nagumo neural network and prove that in the regime where short-range interactions dominate, the probability density of the potential throughout the network concentrates into a…

偏微分方程分析 · 数学 2023-06-13 Alain Blaustein

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

神经元与认知 · 定量生物学 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

First time in six decades, uncountable infinite exact solutions of FitzHugh-Nagumo model with diffusion have been found. FitzHugh-Nagumo model is a nonlinear dynamical system applicable to neurosciences, chemical kinetics, cell division,…

动力系统 · 数学 2024-07-24 Shahid Sultan Ali Ramji , Eddy Kwessi , Mujahid Abbas

According to the conventional approach to model neural ensembles the extracellular environment has fixed ionic concentrations. However, in many cases the extracellular concentration of potassium ions can not be regarded as constant. That…

无序系统与神经网络 · 物理学 2015-05-13 D. E. Postnov , F. Müller , R. B. Schuppner , L. Schimansky-Geier

A commonly accepted feature of an excitable medium is that a local excitation leads to a propagation of circular or spiral excitation wave-fronts. This is indeed the case in fully excitable medium. However, with a decrease of an…

新兴技术 · 计算机科学 2019-04-16 Andrew Adamatzky

We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain. We analyze the bifurcation structure of a system of two model neurons with…

动力系统 · 数学 2019-03-27 Elizabeth N. Davison , Zahra Aminzare , Biswadip Dey , Naomi Ehrich Leonard

We analyze several aspects of the phenomenon of stochastic resonance in reaction-diffusion systems, exploiting the nonequilibrium potential's framework. The generalization of this formalism (sketched in the appendix) to extended systems is…

统计力学 · 物理学 2016-08-14 Horacio S. Wio , Roberto R. Deza

In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed. We address this unrealistic property by developing a hyperbolic bidomain model that is based…

数值分析 · 数学 2017-10-11 Simone Rossi , Boyce E. Griffith

Models of pulse formation in nerve conduction have provided manifold insight not only into neuronal dynamics but also the non-linear dynamics of pulse formation in general. Recent observation of neuronal electro-chemical pulses also driving…

斑图形成与孤子 · 物理学 2023-06-07 Adrian Misselwitz , Suzanne Lafon , Jean-Daniel Julien , Karen Alim

In this article, we discuss the dynamics of the 3-dimensional FitzHugh-Rinzel (FHR) model and a class of non-homogeneous FitzHugh-Nagumo (Nh-FHN) Reaction-Diffusion systems. The Nh-FHN models can be used to generate relevant wave…

斑图形成与孤子 · 物理学 2022-05-10 B. Ambrosio , M. A. Aziz-Alaoui , Argha Mondal , Arnab Mondal , Sanjeev K. Sharma , Ranjit K. Upadhyay

We investigate diffusion-driven instabilities in a FitzHugh-Nagumo reaction-diffusion system with superdiffusive transport, modeled by fractional Laplacian operators with different diffusion orders for the activator and the inhibitor. A…

斑图形成与孤子 · 物理学 2026-03-04 Rossella Rizzo , Gaetana Gambino , Vincenzo Sciacca , Marco Sammartino

We calculate the plasma excitations in a bundle as well as a two-dimensional (2D) periodic array of aligned parallel multishell nanotubes on a substrate. The carbon nanotubes are oriented perpendicular to the substrate. The model we use for…

介观与纳米尺度物理 · 物理学 2015-05-18 Tibab McNeish , Godfrey Gumbs , Antonios Balassis

The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

软凝聚态物质 · 物理学 2019-02-27 Pierra A. Haas , Raymond E. Goldstein