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It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

概率论 · 数学 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston

In 2010, Anderson, Craciun, and Kurtz showed that if a deterministically modeled reaction network is complex balanced, then the associated stochastic model admits a stationary distribution that is a product of Poissons \cite{ACK2010}. That…

概率论 · 数学 2017-12-21 David F. Anderson , Tung D. Nguyen

Reaction networks are widely used models to describe biochemical processes. Stochastic fluctuations in the counts of biological macromolecules have amplified consequences due to their small population sizes. This makes it necessary to favor…

概率论 · 数学 2022-02-28 Daniele Cappelletti , Badal Joshi

We consider discrete-space continuous-time Markov models of reaction networks and provide sufficient conditions for the following stability condition to hold: each state in a closed, irreducible component of the state space is positive…

概率论 · 数学 2018-08-23 David F. Anderson , Jinsu Kim

This paper is Part I of a two-part series devoting to the study of systematic measures in a complex biological network modeled by a system of ordinary differential equations. As the mathematical complement to our previous work [31] with…

概率论 · 数学 2016-06-13 Yao Li , Yingfei Yi

In the paper, stationary measures of stochastic differential equations with jumps are considered. Under some general conditions, existence of stationary measures is proved through Markov measures and Lyapunov functions. Moreover, for two…

概率论 · 数学 2014-02-18 Huijie Qiao , Jinqiao Duan

We consider smooth random dynamical systems defined by a distribution with a finite moment of the norm of the differential, and prove that under suitable non-degeneracy conditions any stationary measure must be H\"older continuous. The…

动力系统 · 数学 2022-09-27 Anton Gorodetski , Victor Kleptsyn , Grigorii Monakov

Stochastic contraction analysis is a recently developed tool for studying the global stability properties of nonlinear stochastic systems, based on a differential analysis of convergence in an appropriate metric. To date, stochastic…

最优化与控制 · 数学 2013-04-02 Quang-Cuong Pham , Jean-Jacques Slotine

In this paper I show that, for a class of reaction networks, the discrete stochastic nature of the reacting species and reactions results in qualitative and quantitative differences between the mean of exact stochastic simulations and the…

其他定量生物学 · 定量生物学 2008-01-03 Chetan J Gadgil

Deciding whether and where a system of parametrized ordinary differential equations displays bistability, that is, has at least two asymptotically stable steady states for some choice of parameters, is a hard problem. For systems modeling…

分子网络 · 定量生物学 2020-08-31 Angélica Torres , Elisenda Feliu

Given the significance of physical measures in understanding the complexity of dynamical systems as well as the noisy nature of real-world systems, investigating the stability of physical measures under noise perturbations is undoubtedly a…

动力系统 · 数学 2025-06-24 Weiwei Qi , Zhongwei Shen , Yingfei Yi

Reaction networks taken with mass-action kinetics arise in many settings, from epidemiology to population biology to systems of chemical reactions. Bistable reaction networks are posited to underlie biochemical switches, which motivates the…

动力系统 · 数学 2016-09-20 Badal Joshi , Anne Shiu

Stochastic resonance holds much promise for the detection of weak signals in the presence of relatively loud noise. Following the discovery of nondynamical and of aperiodic stochastic resonance, it was recently shown that the phenomenon can…

凝聚态物理 · 物理学 2009-10-31 Redouane Fakir

Stationarity is a very general, qualitative assumption, that can be assessed on the basis of application specifics. It is thus a rather attractive assumption to base statistical analysis on, especially for problems for which less general…

统计理论 · 数学 2019-04-02 Daniil Ryabko

There has been significant progress recently in our understanding of the stationary measures of the exclusion process on $Z$. The corresponding situation in higher dimensions remains largely a mystery. In this paper we give necessary and…

概率论 · 数学 2007-05-23 M. Bramson , T. M. Liggett

A stochastic model for a chemical reaction network is embedded in a one-parameter family of models with species numbers and rate constants scaled by powers of the parameter. A systematic approach is developed for determining appropriate…

概率论 · 数学 2010-11-09 Hye-Won Kang , Thomas G. Kurtz

In this paper we present a stability criterion for finite measure-valued stochastic recursions, generalizing Loynes's Theorem to spaces of measures. This result provides conditions for the reach of a "total stationary state" for the queue…

概率论 · 数学 2010-09-08 Pascal Moyal

We study the multistationarity for the reaction networks with one-dimensional stoichiometric subspaces, and we focus on the networks admitting finitely many positive steady states. We prove that if a network admits multistationarity, then…

动力系统 · 数学 2021-08-24 Kexin Lin , Xiaoxian Tang , Zhishuo Zhang

Controlling complex reaction networks is a fundamental challenge in the fields of physics, biology, and systems engineering. Here, we prove a general principle for catalytic reaction systems with kinetics where the reaction order and the…

We study transient patterns appearing in a class of SPDE using the framework of quasi-stationary and quasi-ergodic measures. In particular, we prove the existence and uniqueness of quasi-stationary and quasi-ergodic measures for a class of…

概率论 · 数学 2024-06-19 Zachary P. Adams