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Biochemical reactions with oscillatory behavior play an essential role in synthetic biology at the microscopic scale. Although a robust stability theory for deterministic chemical oscillators in the macroscopic limit exists, the dynamical…

分子网络 · 定量生物学 2019-02-27 Pedro H. Constantino , Yiannis N. Kaznessis

In many non-linear systems, such as plasma oscillation, boson condensation, chemical reaction, and even predatory-prey oscillation, the coarse-grained dynamics are governed by an equation containing anti-symmetric transitions, known as the…

量子物理 · 物理学 2019-06-05 Xi Yong , Man-Hong Yung , Xue-Ke Song , Xun Gao , Angsheng Li

We consider a network of four non-identical chaotic Rossler oscillators. The possibility is shown of appearance of two-, three- and four-frequency invariant tori resulting from secondary quasi-periodic Hopf bifurcations and saddle-node…

混沌动力学 · 物理学 2014-10-30 Alexander P. Kuznetsov , Igor R. Sataev , Yuliya V. Sedova , Ludmila V. Turukina

In epidemiological modelling, dynamics on networks, and in particular adaptive and heterogeneous networks have recently received much interest. Here we present a detailed analysis of a previously proposed model that combines heterogeneity…

物理与社会 · 物理学 2016-09-21 Hui Yang , Tim Rogers , Thilo Gross

Mathematical Epidemiology (ME) shares with Chemical Reaction Network Theory (CRNT) the basic mathematical structure of its dynamical systems. Despite this central similarity, methods from CRNT have been seldom applied to solving problems in…

动力系统 · 数学 2024-05-30 Nicola Vassena , Florin Avram , Rim Adenane

In this paper, we present a method of higher-order analysis on bifurcation of small limit cycles around an elementary center of integrable systems under perturbations. This method is equivalent to higher-order Melinikov function approach…

动力系统 · 数学 2017-08-29 Yun Tian , Pei Yu

The neural oscillator model proposed by Matsuoka is a piecewise affine system, which exhibits distinctive periodic solutions. Although such typical oscillation patterns have been widely studied, little is understood about the dynamics of…

适应与自组织系统 · 物理学 2024-11-06 Kotaro Muramatsu , Hiroshi Kori

We describe combinatorial approaches to the question of whether families of real matrices admit pairs of nonreal eigenvalues passing through the imaginary axis. When the matrices arise as Jacobian matrices in the study of dynamical systems,…

组合数学 · 数学 2013-09-02 David Angeli , Murad Banaji , Casian Pantea

Zero-one biochemical reaction networks play key roles in cell signalling such as signalling pathways regulated by protein phosphorylation. Multistability of reaction networks is a crucial dynamics feature enabling decision-making in cells.…

动力系统 · 数学 2024-12-20 Yue Jiao , Xiaoxian Tang , Xiaowei Zeng

Cyclic patterns of neuronal activity are ubiquitous in animal nervous systems, and partially responsible for generating and controlling rhythmic movements such as locomotion, respiration, swallowing and so on. Clarifying the role of the…

神经与进化计算 · 计算机科学 2013-08-26 Chuan Zhang , Gerhard Dangelmayr , Iuliana Oprea

We study collective dynamics of complex networks of stochastic excitable elements, active rotators. In the thermodynamic limit of infinite number of elements, we apply a mean-field theory for the network and then use a Gaussian…

混沌动力学 · 物理学 2013-11-19 Bernard Sonnenschein , Michael A. Zaks , Alexander B. Neiman , Lutz Schimansky-Geier

For many physical systems the transition from a stationary solution to sustained small amplitude oscillations corresponds to a Hopf bifurcation. For systems involving impacts, thresholds, switches, or other abrupt events, however, this…

动力系统 · 数学 2019-05-07 David J. W. Simpson

In the study of reaction networks and the polynomial dynamical systems that they generate, special classes of networks with important properties have been identified. These include reversible, weakly reversible}, and, more recently,…

We study the multistationarity for the reaction networks with one-dimensional stoichiometric subspaces, and we focus on the networks admitting finitely many positive steady states. We prove that if a network admits multistationarity, then…

动力系统 · 数学 2021-08-24 Kexin Lin , Xiaoxian Tang , Zhishuo Zhang

Some results are presented on how oscillation is inherited by chemical reaction networks (CRNs) when they are built in natural ways from smaller oscillatory networks. The main results describe four important ways in which a CRN can be…

动力系统 · 数学 2017-11-07 Murad Banaji

We study a system of coupled phase oscillators near a saddle-node on an invariant circle bifurcation and driven by random intrinsic frequencies. Under the variation of control parameters, the system undergoes a phase transition changing the…

适应与自组织系统 · 物理学 2022-08-18 Georgi S. Medvedev , Matthew S. Mizuhara , Andrew Phillips

Mixed mode oscillations (MMOs) are complex oscillatory behaviors of multiple-timescale dynamical systems in which there is an alternation of large-amplitude and small-amplitude oscillations. It is well known that MMOs in two-timescale…

动力系统 · 数学 2024-03-01 Ngoc Anh Phan , Yangyang Wang

Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

分子网络 · 定量生物学 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

We study analytically the dynamics of a network of sparsely connected inhibitory integrate-and-fire neurons in a regime where individual neurons emit spikes irregularly and at a low rate. In the limit when the number of neurons N tends to…

无序系统与神经网络 · 物理学 2007-05-23 N. Brunel , V. Hakim

The activation of matrix metalloproteinase 2 (MMP2) is a crucial event during tumor metastasis and invasion, and this pathway network consists of 3 monomers. The pathway network of the activation obeys to a set of specified reaction rules.…

生物大分子 · 定量生物学 2018-03-08 Keiko Itano