相关论文: Optimal Mitigation of SIR Epidemics Under Model Un…
We give the explicit solution of the optimal control problem which consists in minimizing the epidemic peak in the SIR model when the control is an attenuation factor of the infectious rate, subject to a L 1 budget constraint. The optimal…
Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…
Information spreading in a population can be modeled as an epidemic. Campaigners (e.g. election campaign managers, companies marketing products or movies) are interested in spreading a message by a given deadline, using limited resources.…
Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…
We analyze the identifiability and observability of the well-known SIR epidemic model with an additional compartment Q of the sub-population of infected individuals that are placed in quarantine (SIQR model), considering that the flow of…
During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…
Pandemics involve the high transmission of a disease that impacts global and local health and economic patterns. The impact of a pandemic can be minimized by enforcing certain restrictions on a community. However, while minimizing infection…
We study first order necessary conditions for an optimal control problem of a Susceptible-Infected-Recovered (SIR) model with limitations on the duration of the quarantine. The control is done by means of the reproduction number, i.e., the…
In this project, identifiability, observability and uncertainty properties of the deterministic and Chain Binomial stochastic SIR, SEIR and SEIAR epidemiological models are studied. Techniques for modeling overdispersion are investigated…
The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…
The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…
Understanding the dynamics of an epidemic spread is crucial for effective control measures. During the COVID-19 pandemic, quarantines were implemented to minimize infections while mitigating social and economic impacts, raising the question…
We study the classic Susceptible-Infected-Recovered (SIR) model for the spread of an infectious disease. In this stochastic process, there are two competing mechanism: infection and recovery. Susceptible individuals may contract the disease…
The study of social networks, and in particular the spread of disease on networks, has attracted considerable recent attention in the physics community. In this paper, we show that a large class of standard epidemiological models, the…
The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…
Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…
The adoption of prophylaxis attitudes, such as social isolation and use of face masks, to mitigate epidemic outbreaks strongly depends on the support of the population. In this work, we investigate a susceptible-infected-recovered (SIR)…
The spread of an epidemic is often modeled by an SIR random process on a social network graph. The MinINF problem for optimal social distancing involves minimizing the expected number of infections, when we are allowed to break at most $B$…
Case isolation, that is, detection and isolation of infected individuals in order to prevent spread, is a strategy to curb infectious disease epidemics. Here, we study the efficiency of a case isolation strategy subject to time delays in…
This paper considers a stochastic SIR (susceptible$\to$infective$\to$removed) epidemic model in which individuals may make infectious contacts in two ways, both within `households' (which for ease of exposition are assumed to have equal…