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In this paper we study a bilinear optimal control problem associated to a chemo-repulsion model with linear production term. We analyze the existence, uniqueness and regularity of pointwise strong solutions in a bidimensional domain. We…

In this paper, we study an optimal control problem for a coupled non-linear system of reaction-diffusion equations with degenerate diffusion, consisting of two partial differential equations representing the density of cells and the…

最优化与控制 · 数学 2024-07-11 Georges Chamoun , Mazen Saad , Toni Sayah , Sarah Serhal

We consider a bilinear optimal control problem associated to the following chemotaxis-consumption model in a bounded domain $\Omega \subset \mathbb{R}^3$ during a time interval $(0,T)$: $$\partial_t u - \Delta u = - \nabla \cdot (u \nabla…

最优化与控制 · 数学 2023-10-26 Francisco Guillén-González , André Luiz Corrêa Vianna Filho

In the present work we investigate an optimal control problem related to the following chemotaxis-consumption model in a bounded domain $\Omega\subset \mathbb{R}^3$: $$\partial_t u - \Delta u = - \nabla \cdot (u \nabla v), \quad \partial_t…

最优化与控制 · 数学 2024-02-12 Francisco Guillén-González , André Luiz Corrêa Vianna Filho

In this paper, we consider an optimal bilinear control problem for the nonlinear Schr\"{o}dinger equations with singular potentials. We show well-posedness of the problem and existence of an optimal control. In addition, the first order…

偏微分方程分析 · 数学 2013-01-21 Binhua Feng , Dun Zhao , Pengyu Chen

In this work we introduce a new optimal control algorithm for the Keller-Segel chemo-attraction system, where both boundary and distributed controls are considered and both are associated with introducing/removing the amount of chemical…

最优化与控制 · 数学 2026-03-20 F. Guillen-Gonzalez , F. Palmero-Ramos , M. A. Rodriguez-Bellido , G. Tierra

In this paper we study the following three-dimensional parabolic-parabolic chemo-repulsion model with potential production, logistic reaction and bilinear control, defined in $Q=(0,T)\times\Omega$: \begin{equation*}\label{eq0} \left\{…

In this work, we will investigate the question of optimal control for bilinear systems with constrained endpoint. The optimal control will be characterized through a set of unconstrained minimization problems that approximate the former.…

最优化与控制 · 数学 2021-07-28 Soufiane Yahyaoui , Lahoussine Lafhim , Mohamed Ouzahra

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

最优化与控制 · 数学 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We study the solutions of the two-dimensional Keller-Segel system describing chemotaxis. The Keller-Segel system as well as the properties of the blow-up set has been extensively studied. In this paper we obtain generalized solutions for…

偏微分方程分析 · 数学 2010-11-02 S. Luckhaus , Y. Sugiyama , J. J. L. Velázquez

In this paper we study a bilinear optimal control problem associated to a 3D chemo-repulsion model with linear production. We prove the existence of weak solutions and we establish a regularity criterion to get global in time strong…

The mathematical modeling of numerous real-world applications results in hierarchical optimization problems with two decision makers where at least one of them has to solve an optimal control problem of ordinary or partial differential…

最优化与控制 · 数学 2019-06-20 Patrick Mehlitz , Gerd Wachsmuth

In this paper, we study chemotaxis effect vs logistic dampening on boundedness for the two-dimensional minimal Keller-Segel model with logistic source in a 2-D smooth and bounded domain. It is well-known that this model allows only for…

偏微分方程分析 · 数学 2018-07-18 Hai-Yang Jin , Tian Xiang

We consider constrained bilinear optimal control of second-order linear evolution partial differential equations (PDEs) with a reaction term on the half line, where control arises as a time-dependent reaction coefficient and constraints are…

计算物理 · 物理学 2025-11-20 Zhexian Li , Felipe de Barros , Ketan Savla

We consider a bilinear optimal control for an evolution equation involving the fractional Laplace operator of order $0<s<1$. We first give some existence and uniqueness results for the considered evolution equation. Next, we establish some…

最优化与控制 · 数学 2024-11-26 Gisèle Mophou , Cyrille Kenne , Mahamadi Warma

This paper concerns a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis with possibly singular potentials, where the control and state variables are nonlinearly coupled. First, we…

最优化与控制 · 数学 2023-06-06 Pierluigi Colli , Andrea Signori , Jürgen Sprekels

It is known that in two dimensions the classical Keller-Segel model can lead to cell aggregation. This behavior can be controlled by adding a logistic growth term with quadratic decay. Researchers have tried to find weaker damping…

偏微分方程分析 · 数学 2026-03-17 Nohayla Alaoui , Mohamed Halloumi , Giuseppe Viglialoro

This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…

偏微分方程分析 · 数学 2024-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We propose and analyze an optimal control problem associated with a Keller-Segel type parabolic system with chemoattraction, modeling the glioblastoma growth in a bi-dimensional bounded domain, influenced by the presence of oxygen where the…

The Keller-Segel model is a system of partial differential equations that describes the movement of cells or organisms in response to chemical signals, a phenomenon known as chemotaxis. In this study, we analyze a doubly parabolic…

偏微分方程分析 · 数学 2025-03-27 Anne Caroline Bronzi , Crystianne Lilian de Andrade
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