相关论文: A nonlocal model describing tumor angiogenesis
In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for…
Models of tumor growth, now commonly used, present several levels of complexity, both in terms of the biomedical ingredients and the mathematical description. The simplest ones contain competition for space using purely fluid mechanical…
In this paper, we formulate a geometric theory of the mechanics of arterial growth. An artery is modeled as a finite-length thick shell that is made of an incompressible nonlinear anisotropic solid. An initial radially-symmetric…
A mathematical model of infiltrative tumour growth taking into account cell proliferation, death and motility is considered. The model is formulated in terms of local cell density and nutrient (oxygen) concentration. In the model the rate…
In this paper, the initial value problem of the convection-diffusion equation of Burgers type is treated. In the asymptotic profile of solutions, the nonlinearity of the equation is reflected. Regarding the solutions to this model, the…
This paper is concerned with a nonlinear free boundary problem modeling the growth of spherically symmetric tumors with angiogenesis, set with a Robin boundary condition. In which, both nonnecrotic tumors and necrotic tumors are taken into…
Burgers equation is a classic model, which arises in numerous applications. At its very core it is a simple conservation law, which serves as a toy model for various dynamics phenomena. In particular, it supports explicit heteroclinic…
In this paper, we study a nonlinearly coupled initial-boundary value problem describing the evolution of brain tumor growth including lactate metabolism. In our modeling approach, we also take into account the viscoelastic properties of the…
We study problems in which a local model is coupled with a nonlocal one. We propose two energies: both of them are based on the same classical weighted $H^1$-semi norm to model the local part, while two different weighted $H^s$-semi norms,…
In \cite{CordobaCordobaFontelos05}, C\'ordoba, C\'ordoba, and Fontelos proved that for some initial data, the following nonlocal-drift variant of the 1D Burgers equation does not have global classical solutions \[ \partial_t \theta +u \;…
In the present article we demonstrate a new hybrid model of tumor growth. Our model is stochastic by tumor population development and strongly deterministic in cell motility dynamics and spatial propagation. In addition, it has excellent…
In this note, we propose a discrete model to study one-dimensional transport equations with non-local drift and supercritical dissipation. The inspiration for our model is the equation $$ \theta_t + (H\theta) \theta_x +(-\Delta)^\alpha…
In this paper, we study a system of three evolutionary operator equations involving fractional powers of selfadjoint, monotone, unbounded, linear operators having compact resolvents. This system constitutes a generalization of a phase field…
We consider the Burgers equation on $H=L^2(0,1)$ perturbed by white noise and the corresponding transition semigroup $P_t$. We prove a new formula for $P_tD\varphi$ (where $\varphi:H\to\R$ is bounded and Borel) which depends on $\varphi$…
We present and analyze new multi-species phase-field mathematical models of tumor growth and ECM invasion. The local and nonlocal mathematical models describe the evolution of volume fractions of tumor cells, viable cells (proliferative and…
In this work, we present and analyse a system of coupled partial differential equations, which models tumour growth under the influence of subdiffusion, mechanical effects, nutrient supply, and chemotherapy. The subdiffusion of the system…
Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…
Primary tumors infrequently lead to demise of cancer patients; instead, mortality and a significant degree of morbidity result from the growth of secondary tumors in distant organs (metastasis). It is well-known that malignant tumors induce…
We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…
In the presented paper a family of angiogenesis models, that is a generalisation of Hahnfeldt et al. model is proposed. Considered family of models is a system of two differential equations with distributed time delays. The global existence…