相关论文: A two-strain reaction-diffusion malaria model with…
We investigate a two-strain disease model with amplification to simulate the prevalence of drug-susceptible (s) and drug-resistant (m) disease strains. We model the emergence of drug resistance as a consequence of inadequate treatment, i.e.…
This paper investigates the deterministic extinction and permanence of a family of SEIRS malaria models with multiple random delays, and with a general nonlinear incidence rate. The conditions for the extinction and permanence of the…
This paper investigates the stochastic permanence of malaria and the existence of a stationary distribution for the stochastic process describing the disease dynamics over sufficiently longtime. The malaria system is highly random with…
We introduce a two-strain model with asymmetric temporary immunity periods and partial cross-immunity. We derive explicit conditions for competitive exclusion and coexistence of the strains depending on the strain-specific basic…
The stochastic extinction and stability in the mean of a family of SEIRS malaria models with a general nonlinear incidence rate is presented. The dynamics is driven by independent white noise processes from the disease transmission and…
We present a deterministic mathematical model for malaria transmission with waning immunity. The model consists of five non-linear system of differential equations. We used next generation matrix to derive the basic reproduction number…
We consider a multi-species reaction-diffusion system that arises in epidemiology to describe the spread of several strains, or variants, of a disease in a population. Our model is a natural spatial, multi-species, extension of the…
Many infectious diseases are comprised of multiple strains with examples including Influenza, tuberculosis, and Dengue virus. The time evolution of such systems is linked to a complex landscape shaped by interactions between competing…
In this paper, we study a reaction-diffusion vector-host epidemic model. We define the basic reproduction number $R_0$ and show that $R_0$ is a threshold parameter: if $R_0\le 1$ the disease free steady state is globally stable; if $R_0>1$…
We consider a simple stochastic model for the spread of a disease caused by two virus strains in a closed homogeneously mixing population of size N. The spread of each strain in the absence of the other one is described by the stochastic…
The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…
Malaria is one of the deadliest infectious diseases globally, causing hundreds of thousands of deaths each year. It disproportionately affects young children, with two-thirds of fatalities occurring in under-fives. Individuals acquire…
In this work, two mathematical models for malaria under resistance are presented. More precisely, the first model shows the interaction between humans and mosquitoes inside a patch under infection of malaria when the human population is…
A malaria model is formulated which includes the enhanced attractiveness of infectious humans to mosquitoes, as result of host manipulation by malaria parasite, and the human behavior, represented by insecticide-treated bed nets usage. The…
The aim of this work is to study the effect of diffusion on the stability of the equilibria in a general two-components reaction-diffusion system with Neumann boundary conditions in the space of continuous functions. As by product, we…
We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…
In contrast to the many theoretical studies on the transmission of human-mosquitoes malaria infection, few studies have considered a multiple structure model formulations including (i) the chronological age of humans and mosquitoes…
We study two simple mathematical models of the epidemic. At first, we study the repetitive infection spreading in a simplified SIRS model including the effect of the decay of the acquired immune. The model is an intermediate model of the…
We consider the dynamics of a virus spreading through a population that produces a mutant strain with the ability to infect individuals that were infected with the established strain. Temporary cross-immunity is included using a time delay,…
We examine how spatial heterogeneity combines with mobility network structure to influence vector-borne disease dynamics. Specifically, we consider a Ross-Macdonald-type disease model on $n$ spatial locations that are coupled by host…