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We analyze the optimal control of disease prevention and treatment in a basic SIS model. We develop a simple macroeconomic setup in which the social planner determines how to optimally intervene, through income taxation, in order to…

理论经济学 · 经济学 2019-10-09 Davide La Torre , Tufail Malik , Simone Marsiglio

We propose a versatile model with a flexible choice of control for an early-pandemic outbreak prevention when vaccine/drug is not yet available. At that stage, control is often limited to non-medical interventions like social distancing and…

最优化与控制 · 数学 2024-06-14 Alexandra Smirnova , Xiaojing Ye

We show we can control an epidemic reaction-diffusion on a directed, and heterogeneous, network by redirecting the flows, thanks to the optimisation of well-designed loss functions, in particular the basic reproduction number of the model.…

动力系统 · 数学 2022-02-07 Pierre-Yves Massé , Quentin Laborde , Maria Cherifa , Jules Olayé , Laurent Oudre

We present a control model for an octopus tentacle, based on the dynamics of an inextensible string with curvature constraints and curvature controls. We derive the equations of motion together with an appropriate set of boundary…

最优化与控制 · 数学 2018-11-21 Simone Cacace , Anna Chiara Lai , Paola Loreti

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

社会与信息网络 · 计算机科学 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

We propose a mathematical model for cholera with treatment through quarantine. The model is shown to be both epidemiologically and mathematically well posed. In particular, we prove that all solutions of the model are positive and bounded;…

最优化与控制 · 数学 2017-01-31 Ana P. Lemos-Paiao , Cristiana J. Silva , Delfim F. M. Torres

We investigate infectious disease spreading on scale-free networks using a heterogeneous mean-field approach applied to the susceptible-infected-susceptible model, incorporating a mitigation factor. Individual heterogeneity is incorporated…

统计力学 · 物理学 2026-05-12 João Gabriel Simões Delboni , M. O. Hase

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

最优化与控制 · 数学 2021-10-12 Matthias Ebenbeck , Patrik Knopf

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

概率论 · 数学 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

种群与进化 · 定量生物学 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

Some microbial organisms are known to randomly slip into and out of hibernation, irrespective of environmental conditions [1]. In a (genetically) uniform population a typically very small subpopulation becomes metabolically inactive whereas…

其他定量生物学 · 定量生物学 2010-07-13 Ole Steuernagel , Daniel Polani

In recent papers it has been suggested that human locomotion may be modeled as an inverse optimal control problem. In this paradigm, the trajectories are assumed to be solutions of an optimal control problem that has to be determined. We…

最优化与控制 · 数学 2010-07-26 Yacine Chitour , Frédéric Jean , Paolo Mason

The competitive exclusion principle in epidemiology implies that when competing strains of a pathogen provide complete protection for each other, the strain with the largest reproduction number outcompetes the other strains and drives them…

种群与进化 · 定量生物学 2024-05-17 Nir Gavish

A model with six mutually-exclusive compartments related to Dengue disease is presented. In this model there are three vector control tools: insecticides (larvicide and adulticide) and mechanical control. The problem is studied using an…

最优化与控制 · 数学 2012-07-10 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We consider a susceptible-infected-susceptible (SIS) epidemic model in which a large group of individuals decide whether to adopt partially effective protection without being aware of their individual infection status. Each individual…

系统与控制 · 电气工程与系统科学 2024-10-29 Urmee Maitra , Ashish R. Hota , Philip E. Paré

Propagation of contagion in networks depends on the graph topology. This paper is concerned with studying the time-asymptotic behavior of the extended contact processes on static, undirected, finite-size networks. This is a contact process…

物理与社会 · 物理学 2015-07-03 June Zhang , José M. F. Moura

In this paper we study the interplay between epidemic spreading and risk perception on multiplex networks. The basic idea is that the effective infection probability is affected by the perception of the risk of being infected, which we…

物理与社会 · 物理学 2014-11-26 Franco Bagnoli , Emanuele Massaro

In this paper we propose and study a spatial diffusion model for the control of anthracnose disease in a bounded domain. The model is a generalization of the one previously developed in [14]. We use the model to simulate two different types…

最优化与控制 · 数学 2016-08-08 David Jaurès Fotsa Mbogne , Christopher Thron

We consider a stochastic control problem where the set of strict (classical) controls is not necessarily convex, and the system is governed by a nonlinear backward stochastic differential equation. By introducing a new approach, we…

最优化与控制 · 数学 2008-12-20 Seid Bahlali

This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…

偏微分方程分析 · 数学 2024-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels