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相关论文: Chemical Reaction Networks in a Laplacian Framewor…

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Motivation: A Chemical Reaction Network (CRN) is a set of chemical reactions, which can be very complex and difficult to analyze. Indeed, dynamical properties of CRNs can be described by a set of non-linear differential equations that…

计算工程、金融与科学 · 计算机科学 2021-07-02 Lucia Nasti , Roberta Gori , Paolo Milazzo , Federico Poloni

In this paper we derive a compact mathematical formulation describing the dynamics of chemical reaction networks that are complex-balanced and are governed by mass action kinetics. The formulation is based on the graph of (substrate and…

动力系统 · 数学 2012-12-12 Shodhan Rao , Arjan van der Schaft , Bayu Jayawardhana

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

分子网络 · 定量生物学 2019-07-11 Ozan Kahramanoğulları

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

动力系统 · 数学 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz

We propose a unified framework that allows for the full mechanistic reconstruction of chemical reaction networks (CRNs) from concentration data. The framework utilizes an integral formulation of the differential equations governing the…

数值分析 · 数学 2026-02-13 Abraham Reyes-Velazquez , Stefan Güttel , Igor Larrosa , Jonas Latz

A crisp survey is given of chemical reaction networks from the perspective of general nonlinear network dynamics, in particular of consensus dynamics. It is shown how by starting from the complex-balanced assumption the reaction dynamics…

动力系统 · 数学 2015-02-10 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

We derive the Hessian geometric structure of nonequilibrium chemical reaction networks (CRN) on the flux and force spaces induced by the Legendre duality of convex dissipation functions and characterize their dynamics as a generalized flow.…

化学物理 · 物理学 2022-06-03 Tetsuya J. Kobayashi , Dimitri Loutchko , Atsushi Kamimura , Yuki Sughiyama

Chemical reaction networks (CRNs) exhibit complex dynamics governed by their underlying network structure. In this paper, we propose a novel approach to study the dynamics of CRNs by representing them on species graphs (S-graphs). By…

分子网络 · 定量生物学 2024-04-24 Keisuke Sugie , Dimitri Loutchko , Tetsuya J. Kobayashi

Random graph models have been instrumental in characterizing complex networks, but chemical reaction networks (CRNs) are better represented as hypergraphs. Traditional models of random CRNs often reduce CRNs to bipartite graphs,…

统计力学 · 物理学 2025-07-15 Shesha Gopal Marehalli Srinivas , Massimiliano Esposito , Nahuel Freitas

Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

分子网络 · 定量生物学 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

Chemical reaction networks (CRNs) are directed graphs with reactant or product complexes as vertices, and reactions as arcs. A CRN is weakly reversible if each of its connected components is strongly connected. Weakly reversible networks…

Reaction networks have become a major modelling framework in the biological sciences from epidemiology and population biology to genetics and cellular biology. In recent years, much progress has been made on stochastic reaction networks…

概率论 · 数学 2025-08-14 Linard Hoessly , Carsten Wiuf , Panqiu Xia

A decomposition of a chemical reaction network (CRN) is produced by partitioning its set of reactions. The partition induces networks, called subnetworks, that are "smaller" than the given CRN which, at this point, can be called parent…

分子网络 · 定量生物学 2021-09-15 Lauro L. Fontanil , Eduardo R. Mendoza

Chemical reaction networks (CRN) comprise an important class of models to understand biological functions such as cellular information processing, the robustness and control of metabolic pathways, circadian rhythms, and many more. However,…

分子网络 · 定量生物学 2025-03-25 Dimitri Loutchko , Yuki Sughiyama , Tetsuya J. Kobayashi

Inspired by Anderson et al. [J. R. Soc. Interface, 2014] we study the long-term behavior of discrete chemical reaction networks (CRNs). In particular, using techniques from both Petri net theory and CRN theory, we provide a powerful…

分布式、并行与集群计算 · 计算机科学 2015-06-16 Robert Brijder

Chemical Reaction Networks (CRNs) provide a useful abstraction of molecular interaction networks in which molecular structures as well as mass conservation principles are abstracted away to focus on the main dynamical properties of the…

分子网络 · 定量生物学 2020-07-31 Elisabeth Degrand , François Fages , Sylvain Soliman

The Chemical Reaction Network (CRN) is a well-studied model that describes the interaction of molecules in well-mixed solutions. In 2014, Qian and Winfree [22] proposed the abstract surface chemical reaction network model (sCRN), which…

计算复杂性 · 计算机科学 2024-06-14 Yi-Xuan Lee , Ho-Lin Chen

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

分子网络 · 定量生物学 2012-04-26 Guy Shinar , Martin Feinberg

Much of the theory on chemical-reaction networks (CRNs) has been developed in the ideal-solution limit, where interactions between the solutes are negligible. However, there is a large variety of phenomena in biological cells and…

生物物理 · 物理学 2022-12-09 Ander Movilla Miangolarra , Michele Castellana

Chemical reaction networks (CRNs) are prototypical complex systems because reactions are nonlinear and connected in intricate ways, and they are also essential to understand living systems. Here, I discuss how recent developments in…

统计力学 · 物理学 2020-12-23 Massimiliano Esposito
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