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At the continuous level, we consider two types of tumor growth models: the cell density model, which is based on the fluid mechanical construction, is more favorable for scientific interpretation and numerical simulations; and the free…

偏微分方程分析 · 数学 2019-10-28 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

偏微分方程分析 · 数学 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

In this article we are interested in the boundary stabilization in finite time of one-dimensional linear hyperbolic balance laws with coefficients depending on time and space. We extend the so called "backstepping method" by introducing…

最优化与控制 · 数学 2020-11-30 Jean-Michel Coron , Long Hu , Guillaume Olive , Peipei Shang

We consider a one-dimensional controlled reaction-diffusion equation, where the control acts on the boundary and is subject to a constant delay. Such a model is a paradigm for more general parabolic systems coupled with a transport…

最优化与控制 · 数学 2015-11-11 Delphine Bresch-Pietri , Christophe Prieur , Emmanuel Trélat

Several cellular activities, such as directed cell migration, are coordinated by an intricate network of biochemical reactions which lead to a polarised state of the cell, in which cellular symmetry is broken, causing the cell to have a…

We prove existence, uniqueness, and regularity for a reaction-diffusion system of coupled bulk-surface equations on a moving domain modelling receptor-ligand dynamics in cells. The nonlinear coupling between the three unknowns is through…

偏微分方程分析 · 数学 2017-11-23 Amal Alphonse , Charles M. Elliott , Joana Terra

We simulate the electrical response of multiple disjoint biological 3D cells undergoing an electropermeabilization process. Instead of solving the boundary value problem in the unbounded volume, we reduce it to a system of boundary…

计算工程、金融与科学 · 计算机科学 2024-09-04 Isabel A. Martínez Ávila , Carlos Jerez-Hanckes , Irina Pettersson

A system with equation and dynamic boundary condition of Cahn-Hilliard type is considered. This system comes from a derivation performed in Liu-Wu (Arch. Ration. Mech. Anal. 233 (2019), 167--247) via an energetic variational approach.…

偏微分方程分析 · 数学 2022-08-02 Pierluigi Colli , Takeshi Fukao , Luca Scarpa

In this paper a strongly degenerate parabolic equation derived from a density dependent particle flow model is studied. Furthermore, a free boundary problem and its connection to the strongly degenerate parabolic equation is investigated.…

偏微分方程分析 · 数学 2024-05-28 Li Chen , Simone Göttlich , Nicola Zamponi

This work deals with a parabolic chemotaxis model with nonlinear diffusion and nonlocal reaction source. The problem is formulated on the whole space and, depending on a specific interplay between the coefficients associated to such…

偏微分方程分析 · 数学 2020-04-24 Tongxing Li , Giuseppe Viglialoro

This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…

数学物理 · 物理学 2017-01-20 Andrea Tosin

We consider a two-phase elliptic-parabolic moving boundary problem modelling an evaporation front in a porous medium. Our main result is a proof of short-time existence and uniqueness of strong solutions to the corresponding nonlinear…

偏微分方程分析 · 数学 2017-02-16 Friedrich Lippoth , Georg Prokert

We study a free boundary problem for a parabolic partial differential equation in which the solution is coupled to the moving boundary through an integral constraint. The problem arises as the hydrodynamic limit of an interacting particle…

偏微分方程分析 · 数学 2020-05-20 Julien Berestycki , Éric Brunet , James Nolen , Sarah Penington

We consider the dynamics of an electrostatically actuated thin elastic plate being clamped at its boundary above a rigid plate. The model includes the harmonic electrostatic potential in the three-dimensional time-varying region between the…

偏微分方程分析 · 数学 2015-06-02 Philippe Laurencot , Christoph Walker

This paper is concerned with the mathematical analysis of time-dependent fluid-solid interaction problem associated with a bounded elastic body immersed in a homogeneous air or fluid above a local rough surface. We reformulate the unbounded…

偏微分方程分析 · 数学 2018-07-25 Changkun Wei , Jiaqing Yang

We investigate a parabolic-elliptic chemotaxis-consumption-growth system with a Robin boundary condition imposed on the signal. First, we analyse the steady state problem, then we show that the solutions of the system are global and…

偏微分方程分析 · 数学 2025-04-29 Piotr Knosalla

We study solutions to a variational equation that models heat control on the boundary. This problem can be thought of as the two phase parabolic Signorini problem. We show that when the solution has a sign on the boundary, the study of the…

偏微分方程分析 · 数学 2015-09-14 Mark Allen , Wenhui Shi

In this paper we study asymptotic behavior of solutions for a free boundary problem modeling the growth of tumors containing two species of cells: proliferating cells and quiescent cells. This tumor model was proposed by Pettet et al in…

偏微分方程分析 · 数学 2007-12-18 Shangbin Cui

Bulk-surface systems on evolving domains are studied. Such problems appear typically from modelling receptor-ligand dynamics in biological cells. Our first main result is the global existence and boundedness of solutions in all dimensions.…

偏微分方程分析 · 数学 2023-02-23 Diogo Caetano , Charles M. Elliott , Bao Quoc Tang

We consider a nonlocal semi-linear parabolic equation on a connected exterior domain of the form $\mathbb{R}^N\setminus K$, where $K\subset\mathbb{R}^N$ is a compact "obstacle". The model we study is motivated by applications in biology and…

偏微分方程分析 · 数学 2020-05-29 Julien Brasseur , Jérôme Coville