相关论文: Neural codes, decidability, and a new local obstru…
How does the brain encode spatial structure? One way is through hippocampal neurons called place cells, which become associated to convex regions of space known as their receptive fields: each place cell fires at a high rate precisely when…
Neural codes serve as a language for neurons in the brain. Convex codes, which arise from the pattern of intersections of convex sets in Euclidean space, are of particular relevance to neuroscience. Not every code is convex, however, and…
Neural codes allow the brain to represent, process, and store information about the world. Combinatorial codes, comprised of binary patterns of neural activity, encode information via the collective behavior of populations of neurons. A…
Place cells are neurons that act as biological position sensors, associated with and firing in response to regions of an environment to situate an organism in space. These associations are recorded in (combinatorial) neural codes,…
Neural codes are lists of subsets of neurons that fire together. Of particular interest are neurons called place cells, which fire when an animal is in specific, usually convex regions in space. A fundamental question, therefore, is to…
Neural codes, represented as collections of binary strings, encode neural activity and show relationships among stimuli. Certain neurons, called place cells, have been shown experimentally to fire in convex regions in space. A natural…
Neural codes, represented as collections of binary strings called codewords, are used to encode neural activity. A code is called convex if its codewords are represented as an arrangement of convex open sets in Euclidean space. Previous…
The brain encodes spacial structure through a combinatorial code of neural activity. Experiments suggest such codes correspond to convex areas of the subject's environment. We present an intrinsic condition that implies a neural code may…
Convex neural codes are subsets of the Boolean lattice that record the intersection patterns of convex sets in Euclidean space. Much work in recent years has focused on finding combinatorial criteria on codes that can be used to classify…
A combinatorial neural code is a subset of the power set $2^{[n]}$ on $[n]=\{1,\dots, n\}$, in which each $1\leq i\leq n$ represents a neuron and each element (codeword) represents the co-firing event of some neurons. Consider a space…
A convex code is a binary code generated by the pattern of intersections of a collection of open convex sets in some Euclidean space. Convex codes are relevant to neuroscience as they arise from the activity of neurons that have convex…
Previous work on convexity of neural codes has produced codes that are open-convex but not closed-convex -- or vice-versa. However, why a code is one but not the other, and how to detect such discrepancies are open questions. We tackle…
We introduce new geometric and combinatorial criteria that preclude a neural code from being convex, and use them to tackle the classification problem for codes on six neurons. Along the way, we give the first example of a code that is…
Determining how the brain stores information is one of the most pressing problems in neuroscience. In many instances, the collection of stimuli for a given neuron can be modeled by a convex set in $\mathbb{R}^d$. Combinatorial objects known…
Convex neural codes are combinatorial structures describing the intersection pattern of a collection of convex sets. Inductively pierced codes are a particularly nice subclass of neural codes introduced in the information visualization…
Why do neurons encode information the way they do? Normative answers to this question model neural activity as the solution to an optimisation problem; for example, the celebrated efficient coding hypothesis frames neural activity as the…
This dissertation explores applications of discrete geometry in mathematical neuroscience. We begin with convex neural codes, which model the activity of hippocampal place cells and other neurons with convex receptive fields. In Chapter 4,…
Much work has been done to identify which binary codes can be represented by collections of open convex or closed convex sets. While not all binary codes can be realized by such sets, here we prove that every binary code can be realized by…
A good cover in R^d is a collection of open contractible sets in R^d such that the intersection of any subcollection is either contractible or empty. Motivated by an analogy with convex sets, intersection patterns of good covers were…
It has been studied by Curto et al. (SIAM J. on App. Alg. and Geom., 1(1) : 222 $\unicode{x2013}$ 238, 2017) that a neural code that has an open convex realization does not have any local obstruction relative to the neural code. Further, a…