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In cells and in vitro assays the number of motor proteins involved in biological transport processes is far from being unlimited. The cytoskeletal binding sites are in contact with the same finite reservoir of motors (either the cytosol or…

亚细胞过程 · 定量生物学 2014-09-26 Luca Ciandrini , I. Neri , Jean-Charles Walter , O. Dauloudet , A. Parmeggiani

Myosin II plays a pivotal role in muscle contraction by generating force through the cooperative action of multiple motors on actin filaments. In this study, we integrate the nonlinear elasticity of the neck linker in individual myosin II…

生物物理 · 物理学 2023-06-21 Beibei Shen , Yunxin Zhang

Contractile forces are essential for many developmental processes involving cell shape change and tissue deformation. Recent experiments on reconstituted actomyosin networks, the major component of the contractile machinery, have shown that…

生物物理 · 物理学 2012-05-31 Shenshen Wang , Peter G. Wolynes

Using extended dynamical mean-field theory and its combination with the $GW$ approximation, we compute the phase diagrams and local spectral functions of the single-band extended Hubbard model on the square and simple cubic lattices,…

强关联电子 · 物理学 2014-12-04 Li Huang , Thomas Ayral , Silke Biermann , Philipp Werner

The totally asymmetric simple exclusion process (TASEP) is a stochastic model for the unidirectional flow of interacting particles on a 1D-lattice that is much used in systems biology and statistical physics. Its master equation describes…

动力系统 · 数学 2026-04-20 Kilian Pioch , Lars Grüne , Thomas Kriecherbauer , Michael Margaliot

A paradigmatic framework to study the phenomenon of spontaneous collective synchronization is provided by the Kuramoto model comprising a large collection of limit-cycle oscillators of distributed frequencies that are globally coupled…

适应与自组织系统 · 物理学 2020-09-08 Mrinal Sarkar , Shamik Gupta

The stationary states of systems with many molecular motors are studied theoretically for uniaxial and centered (aster-like) arrangements of cytoskeletal filaments using Monte Carlo simulations and a two-state model. Mutual exclusion of…

亚细胞过程 · 定量生物学 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

Using Monte Carlo simulations and a domain wall theory, we discuss the effect of coupling several totally asymmetric simple exclusion processes (TASEPs) to a finite reservoir of particles. This simple model mimics directed biological…

统计力学 · 物理学 2009-11-25 L. Jonathan Cook , R. K. P. Zia , B. Schmittmann

We revisit the defect-induced nonequilibrium phase transition from a largely homogeneous free-flow phase to a phase-separated congested phase in the sublattice totally asymmetric simple exclusion process (TASEP) with local deterministic…

统计力学 · 物理学 2023-06-27 Gunter M. Schütz

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

统计力学 · 物理学 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

We study a Kuramoto-like model of coupled identical phase oscillators on a network, where attractive and repulsive couplings are balanced dynamically due to nonlinearity in interaction. Under a week force, an oscillator tends to follow the…

适应与自组织系统 · 物理学 2015-01-28 Celso Freitas , Elbert Macau , Arkady Pikovsky

The totally asymmetric simple exclusion process (TASEP) is a paradigmatic stochastic model for non-equilibrium physics, and has been successfully applied to describe active transport of molecular motors along cytoskeletal filaments.…

生物物理 · 物理学 2018-07-25 Mareike Bojer , Isabella R. Graf , Erwin Frey

We consider the dynamics of a bio-filament under the collective drive of motor proteins. They are attached irreversibly to a substrate and undergo stochastic attachment-detachment with the filament to produce a directed force on it. We…

软凝聚态物质 · 物理学 2023-05-12 Chitrak Karan , Debasish Chaudhuri

A protein model with the pairwise interaction energies varying as local environment changes, i.e., including some kinds of collective effect between the contacts, is proposed. Lattice Monte Carlo simulations on the thermodynamical…

软凝聚态物质 · 物理学 2009-11-07 K. Fan , J. Wang , W. Wang

In the context of the celebrated Kuramoto model of globally-coupled phase oscillators of distributed natural frequencies, which serves as a paradigm to investigate spontaneous collective synchronization in many-body interacting systems, we…

适应与自组织系统 · 物理学 2017-09-20 Shamik Gupta

We analyze the combined effect of the long range Coulomb (LRC) interaction and of surface energy on first order density-driven phase transitions in the presence of a compensating rigid background. We study mixed states formed by regions of…

强关联电子 · 物理学 2009-10-31 J. Lorenzana , C. Castellani , C. Di Castro

Driven lattice gases as the ASEP are useful tools for the modeling of various stochastic transport processes carried out by self-driven particles, such as molecular motors or vehicles in road traffic. Often these processes take place in…

统计力学 · 物理学 2017-09-20 Christoph Schiffmann , Cecile Appert-Rolland , Ludger Santen

Mechanically induced unfolding of passive crosslinkers is a fundamental biological phenomenon encountered across the scales from individual macro-molecules to cytoskeletal actin networks. In this paper we study a conceptual model of…

生物物理 · 物理学 2015-01-08 M Caruel , J. -M Allain , L Truskinovsky

Valveless pumping assists in fluid transport in various organisms and engineering systems. In a previous work, to study the actuator impact effects on valveless pumping, we constructed a piecewise-linear lumped-parameter model for a…

流体动力学 · 物理学 2011-06-24 Chi-Chung Wang , Tian-Shiang Yang

We study the flux of totally asymmetric simple exclusion processes (TASEPs) on a twin co-axial square tracks. In this biologically motivated model the particles in each track act as mobile bottlenecks against the movement of the particles…

统计力学 · 物理学 2017-05-30 Sumit Sinha , Debashish Chowdhury